CD8

spinqualitylabelsall models Structure of CD8α (magenta) and CD8β (green) complex with antibody heavy chain (cyan) and light chain (salmon) (PDB entry 3b9k) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function CD8 (or Cluster of Differentiation 8) is a T-cell co-receptor. CD8 binds to class I MHC protein. CD8 exists as 2 isoforms: α and β. CD8 forms a dimer of CD8α and CD8β. The extracellular domain of CD8 has immunoglobulin variable-like conformation. This domain of CD8α interacts with α3 domain of class I MHC enhancing the binding of the T-cell receptor and the target cell. CD8α, CD8β and antibody (3b9k). 3D Structures of CD8 CD8 3D structures

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky