Function
Cardiotoxin or cytotoxin (CTX) is a snake toxin from the Taiwan cobra Naja naja. The cardiotoxin from the Malayan krait is called bucain. CTX perturb the membrane structure of cells by interaction with lipids. [1] For toxins in Proteopedia see Toxins.
Relevance
Cardiotoxin I causes necrosis of skeletal muscle cells.
Cardiotoxin III induces apoptosis in K562 cells.
3D Structures of Cardiotoxin
Cardiotoxin 3D structures
- ↑ Rees B, Samama JP, Thierry JC, Gilibert M, Fischer J, Schweitz H, Lazdunski M, Moras D. Crystal structure of a snake venom cardiotoxin. Proc Natl Acad Sci U S A. 1987 May;84(10):3132-6. PMID:3472200
