Casein kinase

spinqualitylabelsall models Human casein kinase 1γ3 complex with inhibitor (PDB code 4g16) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Casein kinase (CK) is a protein kinase which functions as regulator of signal transduction. CK1 is a serine/threonine kinase with several members: α, β1, γ1, γ2, γ3, δ and ε. CK2 functions in cell cycle control, DNA repair and circadian rhythm regulation. Structural highlights CK2 is a tetramer which contains α and α' subunits (CK2A1 and CK2A2) which are the catalytic ones and two β subunits which are the regulatory ones. CK1 inhibitors bind in the ATP binding pocket. Water molecules are shown as red spheres. 3D Structures of casein kinase Casein kinase 3D structures

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