Chitinase-3-like protein
From Proteopedia
Jump to navigationJump to search
| ||||||||||||
References
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Jaime Prilusky, Joel L. Sussman
Chitinase-3-like protein 1 (YKL-40) or Gp39 or cartilage glycoprotein-39 has a role as an autoantigen in rheumatoid arthritis. See also Diabetes & Hypoglycemia and Inflammation & Rheumatoid Arthritis. The goat, sheep, bovine signaling protein is termed SPG-40, SPS-40 and SPC-40, respectively. For details see Molecular Playground/YKL-40 and YKL-40. Chitin tetramer binding site (water molecules are shown as red spheres; 1hjv).[1] RelevanceChitinase-3-like protein 1 and Chitinase-3-like protein 2 show strong expression in brain of multiple sclerosis patients and might help define the stage of the disease and have a prognostic value[2]. 3D Structures of chitinase-3-like proteinChitinase-3-like protein 3D structures
| ||||||||||||
Michal Harel, Alexander Berchansky, Jaime Prilusky, Joel L. Sussman
This page was last modified 08:22, 27 January 2022.