Concanavalin

spinqualitylabelsall models Concanavalin A complex with trisacchride, Mn+2 (small purple), Cl- (large green) and Ca+2 (small green) ions (large purple) (PDB entry 1qdc) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Concanavalin A (ConA) is a carbohydrate-binding protein from jack-bean (Canavalia ensiformis). It binds to certain sugars and to metal. It is used to characterize glycoproteins on cell surfaces.. Concanavalin B (ConB) is related to chitinase with 40% sequence identity.. Concanavalin BR (ConBR) is ConA from Brazilian jack bean. Concanavalin V (ConV) is a D-mannose/D-glucose-binding lectin. Relevance ConA has therapeutic effect on liver cancer. Structural highlights ConA is the homotetramer with D2 symmetry. ConA contains a metal - Mn+2 and Ca+2 - binding site as well as a sugar binding site. 3D Structures of Concanavalin Concanavalin 3D structures

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