Dihydrolipoamide acetyltransferase

spinqualitylabelsall models Human dihydrolipoamide acetyltransferase binding domain (cyan, green) complex with E3 binding domain (magenta), FAD, CHES and mercaptodthanol (PDB entry 3rnm) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Dihydrolipoamide acetyltransferase (DLAT) or E2 is part of the pyruvate dehydrogenase complex together with pyruvate dehydrogenase (E1) and dihydrolipoyl dehydrogenase (E3). The complex decarboxylates pyruvate thus linking the glycolysis to the citric acid cycle. DLAT catalyzes the transfer of acetyl group to CoA. Human dihydrolipoamide acetyltransferase binding domain with E3 binding domain, FAD, CHES and mercaptodthanol. FAD binding site. Mercaptodthanol binding site. CHES binding site (PDB entry 3rnm), water molecules shown as red spheres.

3D structures of dihydrolipoamide acetyltransferase

3rnm

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