Diphtheria toxin repressor

spinqualitylabelsall models Structure of diphtheria toxin repressor complex with DNA and Co+2 ion (PDB entry 1c0w) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Diphtheria toxin repressor (DtxR) is an iron-dependent repressor which is synthesized by the diphtheria bacterium when it is in iron-poor environment. The DtxR regulates the expression of high affinity iron uptake system. Structural highlights DtxR structure contains an N-terminal domain which contains DNA-binding domain (DBD) with a helix-turn-helix motif, dimerization and metal-binding residues. DtxR contains 2 metal binding sites. First metal binding site. Second metal binding site. A C-terminal domain folds into SH3-like conformation.

3D structures of diphtheria toxin repressor

Updated on 24-February-2019

{"openlevels":0}

• DtxR
  • 1dpr, 1bi1, 1bi2 – CdDtxR – Corynebacterium diphtheriae
    
  • 1g3s, 1g3t, 1p92 – CdDtxR (mutant)
    
  • 1bym, 1qvp, 1qw1 – CdDtxR C terminal - NMR
    
• DtxR complex with metal
  • 2dtr – CdDtxR + Co
    
  • 1bi3, 1bi0 – CdDtxR + Zn
    
  • 1fwz, 1g3y – CdDtxR (mutant) + Zn
    
  • 2tdx, 1xcv, 2qq9, 2qqa, 2qqb, 3glx – CdDtxR (mutant) + Ni
    
  • 1g3w – CdDtxR (mutant) + Cd
    
• DtxR complex with metal and DNA
  • 1ddn, 1f5t – CdDtxR (mutant) + Ni + DNA
    
  • 1c0w – CdDtxR + Co + DNA
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky