FIS protein (Factor for Inversion Stimulation) or DNA-binding protein Fis is a regulatory protein in E. coli that activates ribosomal RNA transcription by binding to RNA promoter and enhances transcription by 5 to 10-fold. FIS binds to a sequence which stimulates hin-mediated DNA inversion and causes DNA bending. FIS affects the bacterial chromosome structure and the initiation of DNA replication. FIS exhibits autoregulation. It is abundant during E. coli exponential growth in rich medium and scarce during the stationary phase[1].
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Updated on 27-July-2021
3jra, 3fis, 4fis, 1ety – EcFIS - Escherichia coli
1f36, 1etk, 1eto, 1etq, 1etv, 1etw, 1etx – EcFIS (mutant)
1fip – EcFIS (mutant) + peptide
3iv5, 3jr9, 3jra, 3jrb, 3jrc, 3jrd, 3jre, 3jrf, 3jrg, 3jrh, 3jri, 4ihv, 4ihw, 4ihx, 4ihy, 5ds9, 5dtd, 5e3l, 5e3m, 5e3n, 5e3o, 6p0s – EcFIS + DNA
6p0t, 6p0u – EcFIS + DNA + exicionase
This page was last modified 10:24, 27 July 2021.