File:BRD Mechanism.jpg
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Bromodomains are epigenetic "readers" that bind to acetylated lysines on N-terminal histone tails. Histone acetylation is a post translational modification that is associated with regions of chromatin that are primed for transcription. Bromodomains bind to these modifications and recruit transcriptional machinery to promote gene expression.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 14:27, 27 April 2025 | | 2,012 × 328 (111 KB) | James Lignos (talk | contribs) | Bromodomains are epigenetic "readers" that bind to acetylated lysines on N-terminal histone tails. Histone acetylation is a post translational modification that is associated with regions of chromatin that are primed for transcription. Bromodomains bind t |
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