Glutamate racemase

spinqualitylabelsall models Structure of glutamate racemase dimer complex with D-glutamate and inhibitor (PDB entry 2jfz) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Glutamate racemase (GR) catalyzes the racemization of L-glutamate to D-glutamate. GR plays a major role in bacterial cell wall biosynthesis and moonlights as gyrase inhibitor. Relevance GR inhibition is used as anti-bacterial target. Structural highlights The binding site of D-glutamate to GR is different from that of the inhibitor binding site. Water molecules shown as red spheres. The latter site is occupied in the native GR by side chains of the enzyme 3D Structures of glutamate racemase Glutamate racemase 3D structures

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