Gramicidin

spinqualitylabelsall models Gramicidin A complex with thiocyanate and K+ ion (purple) (PDB entry 1gmk) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It is produced by the bacteria Bacillus brevis. GCDN S is an antibiotic cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. See theoretical model of Gramicidin Channel in Lipid Bilayer and Gramicidin Channel in Lipid Bilayer (Spanish). Relevance GCDN has bactericidal activity and is used as a topical antibiotic and as topical contraceptive. Structural highlights: Gramicidin A Protein: Chains, chain A in green, chain B in salmon. Non-standard residues: Ethanloamine D-leucine D-valine N-formyl-L-valine Ligands: Methanol, C atom of methanol in cyan. Thiocyanate, C atom of thiocyanate in magenta. K+ ion (in purple).

3D Structures of Gramicidin

Updated on 27-July-2025

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• Gramicidin A
  • Gramicidin Channel in Lipid Bilayer, Gramicidin Channel in Lipid Bilayer (Spanish), 1nrm, 1nru, 1ng8, 1kqe, 1jno, 1jo3, 1jo4, 1mic, 1mag, 1grm - GCDN A – NMR
    
  • 1tkq - GCDN A + mini-GCDN A – NMR
    
  • 1av2 - GCDN A + CsCl
    
  • 1gmk - GCDN A + KCNS
• Gramicidin D
  • 2xdc, 1w5u, 1bdw, 1al4, 1alx, 1alz, 2y5m, 2y6n – GCDN D
    
  • 3lml, 2izq, 4v6f, 3l8l - GCDN D + iodide
    
  • 1c4d - GCDN D + CsCl
    
  • 3zq8 – GCDN D + monovaccenin
• Gramicidin S
  • 1tk2 – GCDN S + subtilisin savinase – Bacillus lentus
  • 8rc7 – GCDN S + urea
    

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