Human rhinovirus

spinqualitylabelsall models Structure of human rhinovirus 14 viral proteins VP1 (sea green), VP2 (blue), VP3 (olive), VP4 (green) (PDB code 4rhv). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Human rhinovirus (HRV) are RNA viruses. The HRV capsid is composed of 4 proteins: VP1, VP2, VP3 and VP4. The capsid structure is that of a icosahedron with 60 copies of each of its viral proteins. Disease HRV are responsible for the majority of cold-like illnesses.

3D structures of human rhinovirus

Updated on 14-September-2025

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• Human rhinovirus 1A
  • 1r1a – HRV1A VP1+VP2+VP3+VP4
    
  • 2hwd, 2hwe, 2hwf – HRV1A VP1+VP2+VP3+VP4 + antiviral agent
    
• Human rhinovirus 2
  • 1fpn – HRV2 VP1+VP2+VP3+VP4
    
  • 8ay4, 8ay5 – HRV2 VP1+VP2+VP3+VP4 – Cryo EM
    
  • 1v9u, 3dpr – HRV2 VP1+VP2+VP3+VP4 + LDL-receptor class A3
    
  • 3vdd – HRV2 VP1+VP2+VP3+VP4 + antiviral agent
    
• Human rhinovirus B5
  • 6sk6 – HRVB5 VP1+VP2+VP3+VP4 – Cryo EM
    
  • 6sk5 – HRVB5 VP1+VP2+VP3+VP4 + antiviral agent – Cryo EM
    
• Human rhinovirus 2A
  • 2m5t – HRV2A proteinase - NMR
    
  • 7ara – HRV2A proteinase + inhibitor
    
• Human rhinovirus 3
  • 1rhi – HRV3 VP1+VP2+VP3+VP4
    
• Human rhinovirus 3C
  • 2xya, 6sk7 – HRV3C proteinase
    
  • 5fx5, 5fx6, 6ffn, 6ffs, 6ku8 – HRV3C proteinase + inhibitor
    
• Human rhinovirus 14
  • 4rhv, 1rmu – HRV14 VP1+VP2+VP3+VP4
    
  • 1r08, 2r04, 2r06, 2r07, 2rm2, 2rmu, 2rr1, 2rs1, 2rs3, 2rs5, 1r09, 1hri, 2hwb, 2hwc, 1hrv, 1na1, 1ncq – HRV14 VP1+VP2+VP3+VP4 + antiviral agent
    
  • 1ruc, 1rud, 1rue, 1ruf, 1rug, 1ruh, 1rui, 1ruj, 1vrh – HRV14 VP1+VP2+VP3+VP4 (mutant) + antiviral agent
    
  • 1rvf – HRV14 VP1+VP2+VP3+VP4 + antibody
    
  • 1d3i – HRV14 VP1+VP2+VP3+VP4 + intercellular adhesion molecule – Cryo-EM
    
  • 1k5m – HRV14 VP1+VP2/V3 of Gp120+VP3+VP4
    
  • 6kyz, 6kz0 – HRV14 3C + antibody
    
  • 6hlt – HRV14 + GCP60
    
  • 7nul, 7num, 7nuo – HRV14 polyprotein – Cryo-EM
    
  • 7nun, 7nuq – HRV14 polyprotein + polynucleotide – Cryo-EM
    
  • 7bg6 – HRV14 polyprotein + RNA – Cryo-EM
    
  • 7bg7 – HRV14 polyprotein + ICAM-1 – Cryo-EM
    
• Human rhinovirus C15
  • 6ppo, 6psf – HRVC15 VP1+VP2+VP3+VP4 + CDHR3 – Cryo EM
    
  • 5x45 – HRVC15 847-983
    
• Human rhinovirus C
  • 5jzg – HRVC VP1 (mutant) +VP3+VP0 – Cryo EM
    
  • 5k0u – HRVC VP1 (mutant) + VP2 +VP3+VP4 – Cryo EM
    
• Human rhinovirus 16
  • 1aym, 1ayn, 1c8m – HRV16 VP1+VP2+VP3+VP4 (mutant)
    
  • 1qju, 1qjx, 1qjy - HRV16 VP1+VP2+VP3+VP4 + antiviral agent
    
  • 1d3e – HRV16 VP1+VP2+VP3+VP4 + intercellular adhesion molecule – Cryo EM
    

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