Im7

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Im7 is a Colicin Immunity Protein that binds to the nuclease domain of Colicin E7, in order to protect the cell producing the Colicin from the DNase Activity. When it binds to colicin E7 it physically blocks off the major dsDNA binding sites[1].

Im7 (grey) complex with colicin E7 (green) and Zn+2 ion (grey) (PDB code 7cei]])

Drag the structure with the mouse to rotate

This structure shows the Immunity protein bound to the ColE7 cytotoxic domain.

See also Colicin Immunity Protein.

  1. ↑ Hsia KC, Chak KF, Liang PH, Cheng YS, Ku WY, Yuan HS. DNA binding and degradation by the HNH protein ColE7. Structure. 2004 Feb;12(2):205-14. PMID:14962381 doi:10.1016/j.str.2004.01.004

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