Isoaspartyl dipeptidase

spinqualitylabelsall models E. coli isoaspartyl dipeptidase complex with aspartylhistidine and Zn+2 ions (PDB code 1ybq) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Isoaspartyl dipeptidase (IadA) catalyzes the hydrolytic cleavage of L-isoaspartyl (L-β-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation. Structural highlights The active site of aspartyl dipeptidase contains the substrate and a binuclear metal center which activates the nucleophilic water molecule.

3D structures of isoaspartyl dipeptidase

Updated on 12-June-2023

1po9, 1pok, 1onw – EcIadA – Escherichia coli
2aqo, 2aqv – EcIadA (mutant)
5lp3 – EcIadA – Cryo EM
5xgw – CpIadA – Colwellia psychrerythraea
5xgx – CpIadA (mutant)
1ybq – EcIadA (mutant) + β-Asp-His
1poj – EcIadA + inhibitor
1onx – EcIadA + aspartate
7cdh – FiIadA – Fervidobacterium islandicum
7cf6 – FiIadA + β-Asp-Leu
8dqn – IadA – Leucothrix mucor

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