MHC II 3D structures

3D structures of MHC II

Updated on 09-December-2025

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• MHC II
  • 1hdm, 2bc4, 3lqz, 4p4r - hMHC II α+β - human
    
  • 1a6a, 3pdo, 3pgc, 3pgd, 5ksu - hMHC II α+β+γ
    
  • 8vrw, 8vsp - hMHC II α+β+γ – Cryo EM
    
  • 1fng, 1lnu, 3cup, 2p24 - mMHC II α+β - mouse
    
  • 1fne - mMHC II α+β (mutant)
    
  • 3lqz - hMHC II α+β DP2
    
  • 8jrk - bMHC II α+β - bat
    
  • 6t3y, 7apz - cMHC II α+β - chicken
    
• MHC II binary complex
  • 1h15 - hMHC II α+β + DNA polymerase peptide
    
  • 1fv1 - hMHC II α+β + myelin basic protein
    
  • 2wbj, 3o6f, 4grl, 6mnn, 6mno - hMHC II α+β + T cell receptor
    
  • 1fv1, 1h15, 1s9v, 1t5w, 1uvq, 2fse, 2q6w, 3l6f, 3c5j, 4h25, 4md0, 4md5, 5nig, 6atf, 6atz, 6bij, 6bil, 6bin, 6biv, 6bix, 6biy, 6blq, 6dig, 6hby, 6nix, 6qzc, 6qzd, 6u3m, 6zwa, 7kei, 7t2a, 7t6i, 7yx9, 7yxb, 7z0q, 7zak, 7zfr, 8pje, 8tbp, 8vdu, 9nih – hMHC II α+β + peptide
    
  • 8vdd – hMHC II α+β (mutant) + peptide
    
  • 8cmb, 8cmc, 8cmd, 8cme, 8cmf, 8cmg, 8cmh, 8cmi – hMHC II α+β + SARS peptide
    
  • 1dlh - hMHC II α+β + enterotoxin
    
  • 8euq, 9b7b - hMHC II α+β + antibody
    
  • 8w83, 8w85, 8w86 - hMHC II α+β (mutant) + antibody
    
  • 3c5z, 3c60, 3c6l, 3rdt, 6dfs, 6dfw, 6mkd, 6mkr, 6py2 - mMHC II α+β + T cell receptor
    
  • 1r5v, 1k2d, 1muj, 1kt2, 1ktd, 1f3j, 1es0, 1iak, 1iea, 1ieb, 1f3j, 7qhp, 8ral - mMHC II α+β + peptide
    
  • 1aqd - mMHC II α+β + MHC I peptide
    
  • 1l3r, 1r5w - mMHC II + (mutant) + peptide
    
  • 8jr4, 8jrj – bMHC II α+β + peptide
    
  • 6kvm, 7pdy – cMHC II α+β + peptide
    
• MHC II ternary complex
  • 1zgl, 1j8h, 1fyt, 1ymm, 2iam, 2ain, 4z7u, 6cql, 6cqn, 6dfx, 6mng, 6mnm, 6r0e, 6u3n, 6u3o, 6v15, 6xc9, 6xco, 7sg0, 7sg1, 7sg2, 7t2b, 7t2c, 7t2d, 8trl, 8trq, 8trr, 9ejh, 9eji, 9nig - hMHC II α+β + T cell receptor + peptide
    
  • 8vcx, 8vcy, 8vd2 - hMHC II α+β (mutant) + T cell receptor + peptide
    
  • 6xp6, 8euq - hMHC II α+β+ + antibody+ peptide
    
  • 1d5m, 1d5x, 1d5z, 1d6e, 1hxy, 1jwm, 1jws, 1jwu, 1klg, 1klu, 1pyw, 1seb, 2seb, 2g9h, 2ipk - hMHC II α+β + enterotoxin + peptide
    
  • 1sje, 1sjh, 1t5x, 1lo5 - hMHC II α+β + enterotoxin (mutant) + peptide
    
  • 8vd0 - hMHC II α+β (mutant) + TCR + peptide
    
  • 9bf9 - hMHC II α+β + LAG3 + peptide
    
  • 1r5i - hMHC II α+β + mycoplasma arthritidis mitogen+ peptide
    
  • 2oje - mMHC II α+β + mycoplasma arthritidis mitogen+ peptide
    
  • 1zgl, 2xn9, 3mbe, 3qib, 3qiu, 3qiw, 7rdv - mMHC I + T cell receptor + peptide
    
  • 1u3h, 2pxy - mMHC II α+β + T cell receptor (mutant) + peptide
    
  • 1jl4 - mMHC II α+β + CD4 + peptide
    
  • 9cyl, 9cym - mMHC II α+β + LAG3 + peptide
    
• MHC II quaternary complex
  • 4c56 - hMHC II α+β + T cell receptor + enterotoxin + hemagglutinin peptide
    
  • 3pl6, 5nme, 6rp9, 6rpa, 6rpb, 8pjf, 8pjg - hMHC II + T cell receptor + β-2-microglobulin + peptide
    
  • 3s4s - hMHC II α+β + CD4 + hemagglutinin peptide
    
  • 8vsj - hMHC II α+β + superantigen + antibody + peptide
    
  • 2icw - mMHC II α+β + T cell receptor + mycoplasma arthritidis mitogen+ hemagglutinin peptide
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel