NADH peroxidase

spinqualitylabelsall models NADH peroxidase containing FAD complex with NAD, 2npx Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D NADH peroxidase (NPO) catalyzes the conversion of NADH to NAD+ using hydrogen peroxide. See NAD. NPO eliminates the potentially toxic hydrogen peroxide and defends the cell against H2O2-mediated oxidative stress. NPO provides an additional pathway for regeneration of NAD+ which is essential to the fermentative metabolism. FAD is the cofactor in this reaction. NAD binding site. Water molrcules are shown as red spheres. NAD/FAD interactions. FAD binding site. Whole binding site. NAD binding pocket. FAD binding pocket.

3D structures of NADH peroxidase

NAD, 1joa – EfNPO – Enterococcus faecalis
2npx – EfNPO + NAD
1nhp, 1nhq, 1nhr, 1nhs, 1f8w – EfNPO (mutant)

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