P73

spinqualitylabelsall models Human p73 DNA-binding domain complex with Tris, glycerol and Zn+2 ion (grey), 2xwc Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D p73 is a protein related to p53 tumor suppressor. It is involved in cell cycle regulation and induction of apoptosis. p73 has several variants differing in their C- or N-terminal. p73 contains DNA-binding domain (DBD residues 112-312); tetramerization domain (TD residues 351-398). Structural highlights 1st Zn coordination site. 2nd Zn coordination site.

3D Structures of p73

Updated on 15-April-2026

Domains - DNA-binding (DBD) 112-311; Tetramerization (TD) 351-398; C-terminal 439-506.

1cok – hp73 C terminal – human – NMR

2kby – hp73 TD – NMR

2wqi, 2wqj, 2wtt - hp73 TD
5hob, 5hoc - hp73 TD (mutant)
2xwc – hp73 DBD (mutant)
2nb1 - hp73 TD (mutant) + hp63 TD (mutant)
9glq – hP73 TD + darpin
8p9c, 8p9d, 8p9e – hp73 TD + h63 TD + darpin
3vd0, 3vd1, 3vd2, 4g82, 4g83, 4guo, 4guq, 5kbd, 7ezj – hp73 DBD + DNA
4a63 – hp73 DBD + apoptosis stimulating of p53 protein

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