Phosphocarrier protein

spinqualitylabelsall models Structure of phosphocarrier protein HPr (PDB entry 1fu0) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Phosphocarrier protein HPr (HPr) is a component of the sugar phosphotransferase system. The system catalyses the phosphorylation of sugars during their translocation across cell membrane. A phosphoryl group is transferred from phosphoenolpyruvate via several enzymes (EI, EII) to HPr. A conserved histidine in the N terminal of HPr is the acceptor of the phosphate. In Gram-positive bacteria HPr there is a conserved serine which is phosphorylated. Phosphocarrier protein NPr (NPr) is a component of the sugar phosphotransferase system. NPr is a phosphoryl transfer protein, homologous to HPr which functions to regulate nitrogen metabolism. Phosphocarrier protein III Glc (PcpIII) is a signal-transducing component of the phosphoenolpyruvate:glycose phosphotransferase system of E. coli. Structural highlights The phosphorylation of Ser46 prohibits the HPr to act as a phosphocarrier in the EI reaction. 3D structures of phosphocarrier protein HPr Phosphocarrier protein HPr 3D structures

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