Phospholipase A2 homolog

spinqualitylabelsall models Phospholipase A2 homolog dimer complex with inhibitor suramin, PEG400, pentaethylene glycol and sulfate (PDB code 4yv5) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Phospholipase A2 homolog or Basic phospholipase A2 homolog is a snake venom with phospholipase A2 (PLA2) sequence homology and structure homology which has almost no PLA2 activity, i.e., cleaving of fatty acids. The loss of PLA2 catalytic activity is due to the substitution of the conserved Asp49 in the active site by Lys49 in the homolog. Disease The venom causes severe muscle necrosis. Structural highlights The complex between PLA2 homolog and the inhibitor suramin shows the inhibitor interacting with both monomers. The water molecules are shown as red spheres. The location of PLA2 active site conserved Asp49 which is substituted by Lys in PLA2 homologs thus rendering PLA2.

3D structures of phospholipase A2 homolog

Phospholipase A2 homolog 3D structures

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky