Pleurotolysin

spinqualitylabelsall models Pleurotoxin A (blue and green) complex with pleurotoxin B (pink) (PDB code 4v3a) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Pleurotolysin (PTL) is a pore-forming cytolysin from Pleurotus ostreatus. PTL is a two-component cytolysin composed of non-associated PTL A (17kDa) and PTL B (59kDa) which cooperatively cause leakage of potassium ions from human erythrocytes and swelling of the cells leading to colloid-osmotic hemolysis. Pleurotoxin A complex with pleurotoxin B (4v3a).

3D structures of pleurotolysin

Updated on 28-May-2026

{"openlevels":0}

• Pleurotolysin A
  • 4v3a – PoPTL – Pleurotus ostreatus
    
• Pleurotolysin B
  • 4oej – PoPTL
    
  • 4ov8 – PoPTL (mutant)
    
  • 9do6, 9do7, 9do8, 9do9, 9doa, 9dob – PoPTL + ostreolysin A6 – Cryo EM
    
• Pleurotolysin A+B
  • 4v2t, 4v3a, 4v3m, 4v3n – PoPTL - CryoEM
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Openfox