RNA polymerase 3D structures
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Updated on 21-December-2024 - For a general description of the protein see RNA polymerase
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- Prokaryotic DNA-dependent RNAP
- 2y0s – SsRNAP – Sulfolobus shibata
- 1ryq - PfRNAP subunit ε - Pyrococcus furiosus
- 1go3 – MjRNAP subunit RPB4, RPB7 - Methanocaldococcus jannaschii
- 1iw7, 1smy, 6asg - TtRNAP subunits α,β,β',ω Thermus thermophilus
- 8hsh - TtRNAP subunits α,β,β',ω - Cryo EM
- 1doq - TtRNAP subunit α
- 3lti– EcRNAP subunit β fragment – Escherichia coli
- 4iqz - EcRNAP subunit β’
- 3k4g, 1coo - EcRNAP subunit α
- 1bdf - EcRNAP subunit α mutant)
- 3lu0 - EcRNAP subunits α,β,β',ω – Electron diffraction
- 2krc - BsRNAP subunit δ N-terminal – Bacillus subtilis – NMR
- 2ly7 - BsRNAP subunit β NMR
- 2m4k - BsRNAP subunit δ NMR
- 4nc7, 4nc8 - BsRNAP subunit δ
- 2max - HpRNAP subunit α - Helicobacter pylori - NMR
- 1qyp – RNAP II C terminal – Thermococcus celer – NMR
- 4kbj – MtuRNAP β subunit – Mycobacterium tuberculosis
- 5uh7 - MtuRNAP subunit β’
- 7z8q - MtuRNAP subunits α,β,β’,ω – Cryo EM
- 4noi – RNAP α subunit – Campylobacter jejuni
- 1hqm – TaRNAP subunits α,β,β',ω Thermus aquaticus
- 2gho - TaRNAP subunits α,β,β'
- 2auj, 2auk - TaRNAP subunit β’
- 1xpp – RNAP subunit L – Thermoplasma acidophilum
- 2waq, 2wb1, 4ayb – SsRNAP
- 3e7h – VcRNAP subunit – Vibrio cholera
- 1ef4 – MtRNAP subunit RPB10 – Methanothermobacter thermautotrophicus
- 1eik - MtRNAP subunit RPB5 – NMR
- 4qiw – TkRNAP subunits a’’+d+e’+f+h+k+l+n+p – Thermococcus kodakarensis
- 6kf3 – TkRNAP subunits a’’+d+e’+f+h+k+l+n+p – Cryo EM
- 4qjf - TkRNAP subunits e’+f
- 4qjv - TkRNAP subunits d+l
- 6eyd, 6f6w – MsRNAP subunits α,β,β',ω - Mycobacterium smegmatis – Cryo EM
- 6vr4 – RNAP – Cellulophaga phage φ
- 7ccg - RNAP subunit δ - Streptomyces albulus
- 7ok0, 7oqy – SaRNAP – Sulfolobus acidocaldarius – Cryo EM
- 8h02 – SeRNAP subunit – Synechococcus elongatus
- 8emb – RNAP subunit ’ si3 domain – Thermosynechococcus vestitus
- 8dkc – RNAP subunits α,β,β',ω - Porphyromonas gingivalis – Cryo EM
- 2y0s – SsRNAP – Sulfolobus shibata
- Prokaryotic DNA-dependent RNAP complex with DNA/RNA or elongation complex
- 4v8s – SsRNAP + DNA
- 3q22, 3q23, 3q24, 4ff1, 4ff2, 4ff3, 4ff4 – RNAP + DNA – Enterobacteria phage N4
- 2o5i, 2o5j, 4gzy, 4gzz, 4xln, 4xlr – TtRNAP subunits α,β,β',ω + DNA +RNA
- 6m6c, 8hsg, 8hsr - TtRNAP in elongation complex – Cryo EM
- 5x22 - TtRNAP subunits α,β,β',ω + DNA + RNA + CMPCPP
- 5x21 - TtRNAP subunits α,β,β',ω + DNA + RNA + antibiotic
- 4wqs, 4xlp, 4xlq, 4xls, 5tjg - TtRNAP subunits α,β,β',ω + DNA
- 2ppb - TtRNAP subunits α,β,β',ω + antibiotic + DNA + RNA + substrate analog
- 4yg2, 4jk1, 4jk2, 4jkr, 4kmu - EcRNAP subunits α,β,β',ω + RNA
- 8aby, 8ac0, 8acp, 8ad1 - EcRNAP in elongation complex + RNA putL – Cryo EM
- 6flp, 6bjs, 6asx, 6alh, 6alf, 6rip, 6ri9, 7q0j, 7q0k, 7tyb, 7xue, 7xug, 7yp9, 8abz, 8ac1, 8ac2, 8eg7, 8eg8, 8egb, 8eh8 , 8eh9, 8eha, 8ehf, 8ehi, 8f1i, 8f1k, 8f3c, 8fix, 8fiy, 8fvr, 8fvw, 8g00, 8g1s, 8g2w, 8g7e, 8pbl - EcRNAP in elongation complex – Cryo EM
- 7ypa - EcRNAP in transcription-termination complex – Cryo EM
- 6rh3 - EcRNAP subunits α,β,β',ω + RNA + DNA + GMP + CTP – Cryo EM
- 4kn4, 4kn7 - EcRNAP subunits α,β,β',ω + RNA + antibiotic
- 6vvv – MsRNAP in translation initiation complex
- 7p5x – MsRNAP in translation initiation complex + PafBC – Cryo EM
- 6vvx, 6vvy, 6vvs, 6vvt, 6vvz – MsRNAP subunits α,β,β',ω + DNA + antibiotic
- 7l7b – RNAP subunits α,β,β',ω + sigma factor SIGA + antibiotic – Clostridia difficalis – Cryo EM
- 8gzg, 8gzh – RNAP elongation complex + sigma factor SIGA – Synechocystic – Cryo EM
- 4v8s – SsRNAP + DNA
- Prokaryotic DNA-dependent RNAP complex with protein
- 3p8b – PfRNAP subunit ε’’ + NusG
- 3qqc - PfRNAP subunits β, ε’’ + NusG
- 2be5- TtRNAP subunits α,β,β’,ω + σ factor + inhibitor
- 2cw0, 5tmf - TtRNAP subunits α,β,β’,ω + σ factor
- 3wod - TtRNAP subunits α,β,β’,ω + σ factor + GP39
- 4mq9 - TtRNAP subunits α,β,β’,ω + σ factor + GE23077
- 5tmc - TtRNAP subunits α,β,β’,ω + σ factor + protein
- 3dxj, 3eql - TtRNAP subunits α,β,β’,ω + σ factor + antibiotic
- 5xj0 - TtRNAP subunits α,β,β’,ω + σ factor + GP39 + GP76
- 4wqt - TtRNAP subunits α,β,β’,ω + RNA cleavage stimulating factor
- 8hsl - TtRNAP subunits α,β,β’,ω + transcription termination factor rho – Cryo EM
- 3mlq - TtRNAP subunit β + transcription-repair coupling factor
- 3woe, 3wof - TtRNAP subunit β + GP39
- 2lmc - EcRNAP subunit β + RNAP inhibitor
- 3mmp - EcRNAP subunit β + EF-TU
- 7egs - EcRNAP subunit β + DNA helicase II 654-720
- 4ljz, 4lk1, 4mey, 4xsx, 4xsy, 4xsz, 4zh2, 4zh3 , 4zh4, 5nwt, 5uag, 5uah, 5uaj, 5ual, 5uaq, 5ui8 - EcRNAP subunits α,β,β’,ω + σ factor
- 6c9y - EcRNAP subunits α,β,β’,ω + σ factor – Cryo EM
- 4mex - EcRNAP subunits α,β,β’,ω + σ factor + salinamide
- 4lk0, 4llg, 4mex, 4yfk, 4yfn, 4yfx - EcRNAP subunits α,β,β’,ω + σ factor + RNAP inhibitor
- 5uac, 6cux - EcRNAP subunits α,β,β’,ω + σ factor + antibiotic
- 6byu - EcRNAP subunits α,β,β’,ω + σ factor + PPAPP
- 5w1s - EcRNAP subunits α,β,β’,ω + σ factor + TRAR
- 6p1k - EcRNAP subunits α,β,β’,ω + RPOD – Cryo EM
- 7xui – EcRNAP in elongation complex + RPOD – Cryo EM
- 6vjs - EcRNAP subunits α,β,β’,ω + RPOD + inhibitor
- 6r9b, 6r9g - EcRNAP subunits α,β,β’,ω + OCR – Cryo EM
- 6n57, 6n58 - EcRNAP subunits α,β,β’,ω + RPOD + TRAR – Cryo EM
- 7w5y - EcRNAP subunits α,β,β’,ω + RPOD + SoxS – Cryo EM
- 7w5w - EcRNAP subunits α,β,β’,ω + RPOD + SoxS + micF DNA – Cryo EM
- 7w5x - EcRNAP subunits α,β,β’,ω + RPOD + SoxS + zwf DNA – Cryo EM
- 5tbz - EcRNAP subunits α,β,β’ + NusG – Cryo EM
- 6xln, 7mko - EcRNAP in elongation complex – Cryo EM
- 7mkp - EcRNAP core – Cryo EM
- 7m8e, 7mkn, 7mkq - EcRNAP subunits α,β,β’,ω + RapA – Cryo EM
- 6fbv - MtuRNAP subunits α,β,β’,ω + σ factor – single particle EM
- 7u22 - MtuRNAP subunits α,β,β’,ω + σ factor SIGA
- 7pp4, 7q4u, 7q59, 7zf2 - MtuRNAP subunits α,β,β’,ω + σ factor SIGB – Cryo EM
- 5zx3 - MtuRNAP subunits α,β,β’,ω + σ factor SIGH
- 3ihq, 1z3e, 3gfk - BsRNAP subunit α + regulatory protein SPX
- 1l9u - TaRNAP subunits α,β,β’,ω + σ factor
- 2jzb – RNAP subunit α + NusA – Yersinia pseudotuberculosis
- 3tbi - RNAP subunit β + GP33 – Enterobacteria phage T4
- 3lpe - MjRNAP subunit ε’’ + NusG
- 6eyd - MsRNAP subunits α,β,β’,ω + σ factor – Cryo EM
- 6yxu, 6yys, 6z11 - MsRNAP subunits α,β,β’,ω + HelD – Cryo EM
- 6kf4 – TkRNAP subunits a’+d+e’+f+h+k+l+n+p + transcription factor E – Cryo EM
- 6wvk, 6zca, 6zfb - BsRNAP subunits α,β,β’,d + HelD – Cryo EM
- 7oq4 - SaRNAP + viral RNAP inhibitory protein – Cryo EM
- 3p8b – PfRNAP subunit ε’’ + NusG
- Prokaryotic DNA-dependent RNAP complex with σ factor + DNA/RNA
- 6lts - TtRNAP subunits α,β,β’,ω + σ factor SIGA + DNA
- 7qxi - TtRNAP subunits α,β,β’,ω + σ factor-54 + DNA – Cryo EM
- 7mlb, 7mli, 7mlj, 7rdq - TtRNAP in elongation complex + σ factor SIGA – Cryo EM
- 4oin, 4oio - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA
- 4oip - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + nucleotide
- 4oiq, 4oir - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + antibiotic
- 4g7h, 4g7o, 4g7z, 4q4z, 5d4d, 5d4e, 5voi, 6p70 - TtRNAP subunits α,β,β’,ω + σ factor + DNA
- 4q5s, 5d4c, 5e17, 5e18, 5vo8, 6p71, 6oy7, 6oy6, 6oy5, 6ow3, 6ovy, 6ovr, 6kqd, 6kqe, 6kqf, 6kqg, 6kqh, 6kql, 6kqm, 6kqn, 6l74 - TtRNAP in elongation complex
- 5i2d - TtRNAP subunits α,β,β’,ω + σ factor + transcriptional regulator + DNA + RNA
- 6cuu - TtRNAP subunits α,β,β’,ω + σ factor + DNA + antibiotic
- 6n62 - EcRNAP subunits α,β,β’,ω + σ factor + DNA
- 6n61 - EcRNAP subunits α,β,β’,ω + σ factor + DNA + capistruin peptide
- 6n60 - EcRNAP subunits α,β,β’,ω + σ factor + DNA + microcin peptide
- 5nsr, 5nss, 6gh6, 6gh5, 6ca0, 6omf, 7mkd, 7mke, 7mki, 7mkj - EcRNAP subunits α,β,β’,ω + σ factor + DNA – Cryo EM
- 5vt0 - EcRNAP subunits α,β,β’,ω + σ factor + RNA – Cryo EM
- 4yln, 4ylo, 4ylp, 5ipl, 5ipm, 5ipn, 6gfw - EcRNAP subunits α,β,β’,ω + σ factor + DNA + RNA
- 6b6h - EcRNAP subunits α,β,β’,ω + σ factor + CAP + DNA + RNA – Cryo EM
- 8hkc - EcRNAP subunits α,β,β’ + σ factor RPOH + DNA – Cryo EM
- 6k4y - EcRNAP subunits α,β,β’,ω + σ factor + MTOH + DNA – Cryo EM
- 7qwp, 8f1j - EcRNAP subunits α,β,β’,ω + σ factor-54 + DNA – Cryo EM
- 7q9v - EcRNAP subunits α,β,β’,ω + σ factor-54 + PspF + DNA – Cryo EM
- 3iyd - EcRNAP subunits α,β,β’,ω + σ factor + catabolite gene activator + DNA
- 4s20 - EcRNAP subunits α,β,β’,ω + σ factor + RAPA + DNA
- 5ms0 - EcRNAP subunits α,β,β’,ω + σ factor + NusB + NusG + NusA + RS10 + DNA – Cryo EM
- 5uha, 6vw0, 7rwi - MtuRNAP subunits α,β,β’,ω + σ factor + DNA
- 5uh9, 5uh8, 6jcy, 6jcx, 6jbq, 6kon, 6koo, 6kop, 6koq, 6tye, 6tyf, 6tyg - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA
- 8e8m, 8e95 - MtuRNAP in elongation complex
- 8hih - MtuRNAP in elongation complex + GlnR – Cryo EM
- 5uhg, 5uhc, 5uh6, 5uh5 - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA + antibiotic
- 5uhd, 5uhb - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + antibiotic
- 5uhf, 5uhe - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA + inhibitor
- 1l9z - TaRNAP subunits α,β,β’,ω + σ factor + DNA
- 8i23, 8i24 - RNAP subunits α,β,β’,ω + σ factor SIGI1 + DNA – Clostridium thermocellum - Cryo EM
- 6lts - TtRNAP subunits α,β,β’,ω + σ factor SIGA + DNA
- Prokaryotic DNA-dependent RNAP complex with protein + DNA/RNA
- 3aoh, 3aoi - TtRNAP subunits α,β,β’,ω + DNA + RNA + GFH1
- 6wox, 6woy, 7eh0, 7eh1, 7eh2 - TtRNAP subunits α,β,β’,ω in transcription complex
- 6m6a, 6m6b - TtRNAP subunits α,β,β’,ω + transcription-repair-coupling factor + DNA – Cryo EM
- 3t72 - EcRNAP subunit β + Pho box DNA + PhoB
- 1lb2, 3n4m - EcRNAP subunit α + DNA + CAP
- 1xs9 - EcRNAP subunit α + DNA + MARA
- 5ciz - EcRNAP subunit α + DNA + CRP
- 3n97 - EcRNAP subunit α C terminal + DNA + σ factor
- 6z9p, 6z9q, 6z9r, 6z9s, 6z9t, 7add, 7ade - EcRNAP in termination transcription complex
- 6vyu - EcRNAP in transcription initiation complex + mRNA
- 6c6u - EcRNAP subunits α,β,β’,ω + NusG + DNA – Cryo EM
- 6vu3, 6vz3 - EcRNAP transcription translation complex + mRNA – Cryo EM
- 6vzj - EcRNAP transcription translation complex + mRNA + tRNA – Cryo EM
- 6vyz - EcRNAP transcription translation complex + NusA + mRNA + tRNA – Cryo EM
- 6vyq, 6vyr, 6vys, 6vyt, 6vyw, 6vyx, 6vyy, 6vz2, 6vz5, 6vz7, 6xdr, 6xgf, 6xij, 6xii - EcRNAP transcription translation complex + NusG + mRNA + tRNA – Cryo EM
- 6x6t, 6x7f, 6x7k, 6x9q, 6xdq - EcRNAP transcription translation complex + NusA + NusG + mRNA + tRNA – Cryo EM
- 6c6t, 6c6s - EcRNAP subunits α,β,β’,ω + RFAH + DNA – Cryo EM
- 6gov - EcRNAP subunits α,β,β’,ω + NusB + NusG + RS10 + DNA – Cryo EM
- 6flq - EcRNAP subunits α,β,β’,ω + NusA + DNA + RNA – Cryo EM
- 6xas - EcRNAP subunits α,β,β’,ω + NusA + helicase rho + DNA + RNA – Cryo EM
- 6xav, 7adb, 7adc - EcRNAP subunits α,β,β’,ω + NusG + helicase rho + DNA + RNA – Cryo EM
- 6alg - EcRNAP subunits α,β,β’,ω + NUN + DNA + RNA – Cryo EM
- 6p19 - EcRNAP subunits α,β,β’,ω + protein Q + DNA + RNA – Cryo EM
- 6jnx - EcRNAP subunits α,β,β’,ω + protein Q + σ factor + DNA – Cryo EM
- 6p18 - EcRNAP subunits α,β,β’,ω + protein Q + σ factor + DNA + RNA – Cryo EM
- 6kj6 - EcRNAP subunits α,β,β’,ω + RPOS + σ factor-binding protein CRL + DNA + RNA – Cryo EM
- 7chw, 8igs - EcRNAP subunits α,β,β’,ω + σ factor-binding protein PROD + DNA – Cryo EM
- 6x26, 6x2f, 6x2n, 6x43, 6x4w, 6x4y, 6x50 - EcRNAP in elongation complex + TRCF – Cryo EM
- 8e3f, 8e6x, 8e6z - EcRNAP in elongation complex + NusG - Cryo EM
- 8g4w, 8g8z - EcRNAP in elongation complex + preQ1 – Cryo EM
- 7uwe - EcRNAP in elongation complex + RNase HII – Cryo EM
- 8igr - EcRNAP in transcription activation complex + phage regulatory protein CII - Cryo EM
- 7vwz - EcRNAP in transcription activation complex + NusA + antitermination protein - Cryo EM
- 7ubm, 7ubn - EcRNAP in transcription antitermination complex + right origin binding protein - Cryo EM
- 7khb, 7khc, 7khe, 7khi - EcRNAP subunits α,β,β’,ω + σ factor RPOD + DNAK suppressor protein + DNA – Cryo EM
- 7bef, 7beg - EcRNAP subunits α,β,β’,ω + σ factor RPOD + RAMA + DNA – Cryo EM
- 6xh7, 7c17 - EcRNAP subunits α,β,β’,ω + σ factor RPOD + CueR + DNA – Cryo EM
- 6xh8 - EcRNAP subunits α,β,β’,ω + σ factor RPOD + CueR + DNA + RNA – Cryo EM
- 6xl5, 6xl9, 6xlj, 6xll, 6xlm - EcRNAP subunits α,β,β’,ω + σ factor RPOD + DNA + RNA – Cryo EM
- 6wmu, 7c97, 7dy6 - EcRNAP subunits α,β,β’,ω + σ factor RPOD + starvation protein + DNA - Cryo EM
- 7d7c - EcRNAP subunits α,β,β’,ω + GP55 + DNA - Cryo EM
- 7d7d - EcRNAP subunits α,β,β’,ω + DNAP clamp + GP55 + DNA - Cryo EM
- 6n4c, 6oul, 7khc, 7khb, 7n4e - EcRNAP subunits α,β,β’,ω + RPOD + DNA – Cryo EM
- 7szj, 7szk - EcRNAP subunits α,β,β’,ω + RPOD + DNA + drug – Cryo EM
- 6ldi - EcRNAP subunits α,β,β’,ω + RPOD + CUER + DNA + RNA – Cryo EM
- 6pb4, 6pb5, 6pb6 - EcRNAP subunits α,β,β’,ω + RPOD + CRP + DNA + RNA – Cryo EM
- 6psq, 6psr, 6pss, 6pst, 6psu, 6psv, 6psw - EcRNAP subunits α,β,β’,ω + RPOD + TRAR + DNA + RNA – Cryo EM
- 6pmi, 6pmj - EcRNAP subunits α,β,β’,ω + FLIA + DNA + RNA – Cryo EM
- 6rin, 6ri7 - EcRNAP subunits α,β,β’,ω + GREB + RNA + DNA – Cryo EM
- 6tqn, 6tqo - EcRNAP subunits α,β,β’,ω in anti-termination complex – Cryo EM
- 7c17 - EcRNAP subunits α,β,β’,ω in transcription complex – Cryo EM
- 7py3, 7pyj, 7pyk - EcRNAP in elongation complex + NusA - Cryo EM
- 7py0, 7py1, 7py8 - EcRNAP in elongation complex + NusG - Cryo EM
- 7py5, 7py6, 7py7 - EcRNAP in elongation complex + NusG + NusA - Cryo EM
- 8e5k, 8e5o - EcRNAP in transcription pre-termination complex + NusG - Cryo EM
- 7c97, 7chw - EcRNAP subunits α,β,β’,ω in promoter-open complex – Cryo EM
- 6j9f - XoRNAP subunits α,β,β’,ω + P7 + DNA + RNA – Xanthomonas oryzae - Cryo EM
- 6j9e - XoRNAP subunits α,β,β’,ω + P7 + DNA + RNA + NusA - Cryo EM
- 6kf9 – TkRNAP subunits a’’+d+e’+f+h+k+l+n+p + transcription factor E + DNA – Cryo EM
- 6dve, 6dvd, 6dvc, 6dvb, 6dv9 - MtuRNAP subunits α,β,β’,ω + σ factor + DNA
- 5zx2 - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA
- 7kin - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RBPA – Cryo EM
- 7kif, 7kim - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RBPA + CARD + Whib7 – Cryo EM
- 6wmp - FtRNAP subunits α,β,β’,ω + RNA + DNA – Francisella tularensis - Cryo EM
- 6wmr, 6wmt - FtRNAP subunits α,β,β’,ω + σ factor-binding protein PROD + starvation protein + macrophage growth locus + DNA - Cryo EM
- 6wvj - BsRNAP in elongation complex - Cryo EM
- 7ckq - BsRNAP subunits α,β,β’,ω + σ factor-binding protein SIGA + multidrug regulator + YkzG + DNA - Cryo EM
- 7f75 - BsRNAP subunits α,β,β’,ω + σ factor-binding protein SIGA + regulator Spx + RNA + DNA - Cryo EM
- 7ye2 - CavRNAP in transcription activation complex – Caulobacter vibrioides - Cryo EM
- 7ye1 - CavRNAP in transcription activation complex + GCRA - Cryo EM
- 7xya, 7xyb – PaRNAP subunits α,β,β’,ω + AlpA peptide + RNA + DNA – Pseudomonas aeruginosa
- 7xyb – PaRNAP subunits α,β,β’,ω + sigma factor RPOS – Cryo EM
- 7f0r, 7xl3, 7xl4 – PaRNAP subunits α,β,β’,ω + sigma factor RPOS + SutA – Cryo EM
- 8e79 - BsRNAP in elongation complex + NusG - Cryo EM
- 8e74, 8e82, 8ehq, 8ej3, 8eoe, 8eof, 8eos, 8eot, 8exy - MtuRNAP in elongation complex + NusG - Cryo EM
- 8h3v - RNAP in transcription activation complex + NusG + NTCA + NTCB + VF1- Cryo EM
- 8dy7, 8dy9 - RNAP subunits α,β,β’,ω + σ factor + DNA + RBPA + WHIA + WHIB – Streptococcus venezuelae - Cryo EM
- 8syi - SeRNAP in elongation complex + NusG - Cryo EM
- 7vpd, 7vpz, 7x74, 7x75, 7x76 - RNAP in elongation complex + ZUR – Streptococcus coelicolor - Cryo EM
- 3aoh, 3aoi - TtRNAP subunits α,β,β’,ω + DNA + RNA + GFH1
- Prokaryotic DNA-dependent RNAP complex with small molecule
- Viral DNA-dependent RNAP
- Eukaryotic DNA-dependent RNAP I
- 8a43 – hRNAP I – human - Cryo EM
- 7oba – hRNAP I + TIF-IA - Cryo EM
- 7obb – hRNAP I + DNA – Cryo EM
- 7ob9, 7vba, 7vbb, 7vbc – hRNAP I in elongation complex – Cryo EM
- 1a1d – yRNAP subunit RPB8 – yeast - NMR
- 2rf4 - yRNAP I subunit RPA4
- 5g5l, 5lmx, 5m3f, 5m3m, 5m5w, 5m5x, 5m5y, 5m64 – yRNAP I – Cryo EM
- 5n5y, 5n5z, 5n60, 5oa1 – yRNAP I + RRN – Cryo EM
- 5n61, 6h68, 6h67 – yRNAP I + RRN + DNA + RNA – Cryo EM
- 5w66, 5w65, 5w64, 5w5y – yRNAP I + transcription initiation factor + DNA + RNA – Cryo EM
- 6tps – yRNAP I in pre-initiation complex – Cryo EM
- 7aoc, 7aod, 7aoe – fyRNAP I – fission yeast – Cryo EM
- 8a43 – hRNAP I – human - Cryo EM
- Eukaryotic DNA-dependent RNAP II
- 1qkl - hRNAP II subunit RPB6
- 7dth - hRNAP II subunit RPB6 - NMR
- 2c35 - hRNAP II subunits RPB4 RPB7 (mutant) – NMR
- 2f3i - hRNAP II subunits RPB8 RPB17 RPABC3 – NMR
- 2ghq, 2ght - hRNAP II subunits RPB1 + hRNAP II C terminal
- 2q5e, 3l0b, 3l0c - hRNAP II C terminal
- 7ozn, 8b3d, 8b3f – pRNAP II – Cryo EM
- 7w82 – cRNAP II - maize
- 7w88 – cRNAP II – Cryo EM
- 7rqs - AtRNAP II – Arabidopsis thaliana - Cryo EM
- 8h40 – RNAP II + NtcA – anabaena – Cryo EM
- 1nik, 1nt9, 1wcm, 2b8k, 3fki, 3qt1, 1i3q, 1i50, 1dzf, 5ip7, 5ip9, 5u5q – yRNAP II
- 3j1n, 4v1n, 5fmf, 5x51, 5x50, 5x4z, 7ozo, 7ozp – yRNAP II – Cryo EM
- 7ked, 7kee, 7kef – yRNAP II
- 1y14 - yRNAP II subunits RPB4 RPB7
- 3ef0, 3ef1 - fyRNAP II subunit α C terminal
- 3h0g – fyRNAP II
- 1qkl - hRNAP II subunit RPB6
- Eukaryotic DNA-dependent RNAP II complex with DNA/RNA
- 8p4e - hRNAP II + RNA + DNA – Cryo EM
- 4boc – hRNAP + DNA
- 5flm – bRNAP II in elongation complex - bovine
- 5oik – bRNAP II + SPT4 + SPT5 + DNA + RNA
- 1i6h, 4a3i - yRNAP II + DNA
- 4v1m, 7mka - yRNAP II + DNA – Cryo EM
- 1r9s, 2ja5, 2ja6, 2ja7, 2ja8, 2nvq, 2nvt, 2nvx, 2nvy, 2nvz, 3gtg, 3gtj, 3gtk, 3gtl, 3gtm, 3gto, 3gtp, 3gtq, 3hov, 3how, 3hox, 3hoy, 3hoz, 3po2, 3po3, 3m3y, 3m4o, 4a3g, 4a93, 4a3b, 4a3c, 4a3d, 4a3e, 4a3f, 4a3j, 4a3k, 4a3l, 4a3m, 4x67, 4x6a, 4y52, 4y7n, 5c3e, 5c44, 5c4a, 5c4j, 5c4x, 6bqf, 6bm4, 6bm2, 6blp, 6blo, 5w51, 5w4u - yRNAP II + RNA + DNA
- 5vvs - yRNAP II + RNA + DNA – Cryo EM
- 1y1w, 1y77, 2r7z, 2r92, 2r93, 3h3v, 3rzd, 3rzo, 3s15, 3s16, 3s17, 3s1m, 3s1n, 3s1q, 3s1r, 3s2d, 3s2h - yRNAP II + RNA
- 2b63 - yRNAP II + nucleotide + RNA
- 2e2i, 2e2j - yRNAP II + nucleotide + DNA
- 2yu9, 3i4m, 3i4n - yRNAP II + nucleotide + DNA + RNA
- 2vum - yRNAP II + inhibitor + DNA + RNA
- 8p4e - hRNAP II + RNA + DNA – Cryo EM
- Eukaryotic DNA-dependent RNAP II complex with protein
- 3o2q, 3o2s – hRNAP II subunit α C-terminal + symplekin
- 3j0k, 5iy6, 5iy7, 5iy8, 5iy9, 5iya, 5iyb, 5iyc, 5iyd – hRNAP II + TFIIF – Cryo EM
- 7dti – hRNAP II subunit RPB6 + TFIIH – NMR
- 6xre – hRNAP II + p53 – Cryo EM
- 2lto - hRNAP II subunit RPB1 + Tudor domain containing protein 3
- 8jal, 8jaq, 8jar, 8jas, 8jau, 8jav – hRNAP II in cullin-RING E3 ubiquitin ligase – Cryo EM
- 7xt7, 7xtd, 7xti – hRNAP II in elongation complex + nucleosome – Cryo EM
- 8bvw, 8byq – hRNAP II in pre-initiation complex + nucleosome – Cryo EM
- 8p4f – hRNAP II in co-transcriptional capping complex – Cryo EM
- 7nvu, 7nvt, 7nvu - pRNAP II + DNA + TFIIA + TFIIF + TATA-box-binding protein – pig - Cryo EM
- 7edx, 7eg7, 7eg8, 7eg9, 7ega, 7egb, 7egc - pRNAP II + DNA + TFIIA + TFIIB + TFIIE + TFIIF + TATA-box-binding protein - Cryo EM
- 7nw0 - pRNAP II + DNA + TFIIB + TFIIH + MAT1 + TATA-box-binding protein - Cryo EM
- 8a40 - pRNAP II in elongation complex + TFIIS - Cryo EM
- 7und – pRNAP II + nucleosome – Cryo EM
- 7okx, 7oky – pRNAP II + RNA + DNA + SPT5 + ELL2 – Cryo EM
- 7ol0 – pRNAP II + RNA + DNA + SPT5 – Cryo EM
- 7oo3 – pRNAP II + RNA + CSA + CSB + DDB1 + UVSSA – Cryo EM
- 7oop, 7opc, 7opd – pRNAP II + RNA + CSA + CSB + DDB1 + UVSSA – Cryo EM
- 7oob – pRNAP II + RNA + CSA + CSB + SPT6 + UVSSA + PAF – Cryo EM
- 6gml – pRNAP II + RNA + DNA + DSIF + NELF – Cryo EM
- 6gmh, 6ted – pRNAP II + RNA + DNA + DSIF + PAF + SPT6 – Cryo EM
- 6exv – pRNAP II + RNA + DNA + amatoxin – Cryo EM
- 8oew – pRNAP II + RNA + DNA + elongin A,B,C – Cryo EM
- 8oeu – pRNAP II + RNA + DNA + SPT6 – Cryo EM
- 8oev, 8of0 – pRNAP II + RNA + DNA + elongin A,B,C + SPT6 – Cryo EM
- 8p4b, 8p4c – pRNAP II in co-transcriptional capping complex – Cryo EM
- 7b7u, 7f4g – pRNAP II + hRPAP2 – Cryo EM
- 7nvs, 7nvy, 7nvz – pRNAP II in pre-initiation complex – Cryo EM
- 7nvr – pRNAP II in pre-initiation complex + hmediator – Cryo EM
- 7b0y – pRNAP II in transcription complex + U1 SNRNP – Cryo EM
- 1pqv, 1y1v, 4bbr, 4bbs - yRNAP II + TFIIS
- 1y1y - yRNAP II + TFIIS + DNA +RNA
- 1r5u, 3k7a, 3k1f - yRNAP II + TFIIB
- 7mk9 - yRNAP II + DNA + TIIF – Cryo EM
- 4v1o, 5fyw, 5fz5, 5sva - yRNAP II + DNA + TIIF + TBP + mediator – Cryo EM
- 2l0i – yRNAP C-terminal + RTT103 – NMR
- 4bxx, 4bxz, 4by1, 4by7 – yRNAP II + RNA + DNA + transcription factor Bye1
- 5vvr - yRNAP II + DNA + RNA + Rad26 – Cryo EM
- 6upx, 6upy, 6upz, 6uq0, 6uq1, 6uq2, 6uq3, 7rim, 7rip, 7riq 7riw, 7rix, 7riy - yRNAP II in elongation complex
- 6inq, 6a5u, 6a5t, 6a5r, 6a5p, 6a5o, 6a5l, 7nkx, 7nky – yRNAP II + DNA + RNA + nucleosome – Cryo EM
- 7ml0, 7ml1, 7ml2, 7ml4, 7o4i, 7o4j, 7o4k, 7o4l, 7o72, 7o73, 7o75 - yRNAP II + DNA + TFIIH + TBP – Cryo EM
- 7kpv – yRNAP II cyclin-like subunit in Cdk8 kinase module – Cryo EM
- 8cen – yRNAP II in pre-initiation complex + mediator – Cryo EM
- 7zs9, 7zsa, 7zsb – yRNAP II in pre-initiation complex + nucleosome – Cryo EM
- 8ceo – yRNAP II in pre-initiation complex + nucleosome + mediator – Cryo EM
- 8h0v, 8h0w – KpRNAP II in chromatosome – Komagataella phaffii - Cryo EM
- 7xse, 7xsx, 7xsz – KpRNAP II in elongation complex + nucleosome - Cryo EM
- 8he5 – KpRNAP II in elongation complex + nucleosome + Rad26 + Elf1- Cryo EM
- 7wbv, 7wbw, 7wbx – KpRNAP II in elongation complex + Elf1 + Spt4/5 - Cryo EM
- 7xn7 – KpRNAP II in elongation complex + Elf1 + Spt4/5 + Spt6 + Spn1 + Paf1C - Cryo EM
- 3o2q, 3o2s – hRNAP II subunit α C-terminal + symplekin
- Eukaryotic DNA-dependent RNAP II complex with small molecule
- Eukaryotic DNA-dependent RNAP III
- 7a6h, 7ae1, 7ae3, 7aea, 7ast, 7d58, 7d59, 7dn3, 7du2, 7fji, 7fjj - hRNAP III – Cryo EM
- 8ity, 8iuh - hRNAP III in pre-initiation complex – Cryo EM
- 2xub, 2xv4 - hRNAP III subunit Rpc3
- 5afq - hRNAP III subunits Rpc3 + Rpc32B
- 7asu, 7asv - hRNAP III subunit Rpc5
- 2dk5 – hRNAP III winged helix domain (mutant) – NMR
- 2yu3 - hRNAP III winged helix domain
- 2dk8 – RNAP III RPC34 domain - mouse – NMR
- 2ckz, 5fj9, 5fja, 6eu3, 6eu2 - yRNAP III - Cryo EM
- 5fj8, 6f41, 7z1m, 7z1n, 7z1o, 8bws - yRNAP III in elongation complex - Cryo EM
- 6f44, 6f42, 6f40, 6eu1 - yRNAP III + DNA – Cryo EM
- 6cnf, 6cnd, 6cnc, 6cnb - yRNAP III + DNA + TFIIIB – Cryo EM
- 5xon - yRNAP III + DNA + RNA + TFIIB + SPT4 + SPT5 – Cryo EM
- 5xog - yRNAP III + DNA + RNA + SPT5 + KOW5 + ELF1 – Cryo EM
- 6eu0 - yRNAP III + DNA + TFIIIB + TATA-box-binding protein – Cryo EM
- 6tut - yRNAP III complex + MAF1 – Cryo EM
- 7z0h, 7z2z, 7z30, 7z31 - yRNAP III complex + Ty1 integrase – Cryo EM
- 7z1l - yRNAP III pre-termination complex – Cryo EM
- 3ayh - fyRNAP III subunit Rpc8+Rpc9
- 7a6h, 7ae1, 7ae3, 7aea, 7ast, 7d58, 7d59, 7dn3, 7du2, 7fji, 7fjj - hRNAP III – Cryo EM
- Eukaryotic DNA-dependent RNAP I+II+III
- 6o9l, 6drd - hRNAP – Cryo EM
- 6rwe, 6ruo, 6rui, 6rrd, 6rqt, 6rql, 6rqh, 6o6c, 6hls - yRNAP – Cryo EM
- 6hlr, 6hlq, 6hko - yRNAP + nucleotide analog – Cryo EM
- 6j51, 6j50, 6j4z, 6j4y, 6j4x, 6j4w, 6ir9 - yRNAP + Elf1 + Spt4 + Spt5 + nucleosome – Cryo EM
- 6i84 - yRNAP + DNA + nucleosome – Cryo EM
- 6gyl, 6gym, 6gyk, 7mei - yRNAP + DNA + TBP + TFIIH – Cryo EM
- 6o9l, 6drd - hRNAP – Cryo EM
- Eukaryotic DNA-dependent RNAP IV
- Eukaryotic DNA-dependent RNAP V
- 8hyj - AtRNAP + KTF1 - Cryo EM
- 8hyj - AtRNAP + KTF1 - Cryo EM
- Eukaryotic DNA-dependent RNAP I+II+III+IV+V
- Eukaryotic DNA-dependent RNAP μ or DNA-directed DNA/RNA polymerase mu
- 4lzd – hRNAP μ
- 4lzg, 4m04, 4m0a, 5twp, 5twq, 5twr, 5tws. 5txx, 5txz, 5tyb, 5tyc, 5tyd, 5tye, 5tyf, 5tyg, 5tyu, 5tyv, 5tyw, 5tyx, 5tyy, 5tyz, 6p1w, 6p1v, 6p1u, 6p1t, 6p1s, 6p1r, 6p1q, 6p1p, 6p1o, 6p1n, 6p1m, 6akh, 6ak9, 6ak8 – hRNAP μ + DNA
- 5vzi, 5vzh, 5vzg, 5vzf, 5vze, 5vzd, 5vzc, 5vzb, 5vza, 5vz9, 5vz8, 5vz7, 6ipg, 6ipf, 6ipe, 6ipd – hRNAP μ (mutant) + DNA + nucleotide
- 5zlc – hRNAP μ + nucleotide
- 6ipn, 6ipm, 6ipl, 6ipk, 6ipj, 6ipi, 6iph, 6ak6, 6ak5, 6aeh, 6aec – hRNAP μ (mutant) + nucleotide
- 4lzd – hRNAP μ
- Eukaryotic DNA-dependent RNAP mitochondrial or MTRPOL
- 7pzp, 7pzr – hRNAP – Cryo EM
- 4boc – hRNAP + DNA
- 6erq, 6erp – hRNAP + DNA + MTTFA + dimethyladenosine transferase
- 3spa - hRNAP + polypeptide
- 7a8p - hRNAP + inhibitor
- 8att, 8atv, 8atw, 8c5s, 8c5u, 8q63 – yRNAP in transcription initiation complex + RNA – Cryo EM
- 8ap1 – yRNAP in transcription initiation complex + GTP – Cryo EM
- 7pzp, 7pzr – hRNAP – Cryo EM
- Eukaryotic DNA primase
- 4lik, 4mhq, 6rb4 - hDNAP small subunit
- 3q36 – hDNAP large subunit
- 5i7m – hDNAP large subunit (mutant)
- 3l9q – hDNAP large subunit P58C domain
- 5dqo – hDNAP large subunit P58C domain (mutant)
- 4rr2 - hDNAP small + large subunit
- 4bpu - hDNAP small (mutant) + large subunit
- 4ehs – HpDNAP C terminal
- 4lim, 4mm2 - yDNAP small subunit
- 3lgb, 6di6, 6dhw - yDNAP large subunit Fe-S domain
- 6du0, 6dtz, 6dtv, 6di2 - yDNAP large subunit Fe-S domain (mutant)
- 7tl2 - yDNAP large subunit C-terminal domain (mutant)
- 4lik, 4mhq, 6rb4 - hDNAP small subunit
- Eukaryotic DNA primase complex
- 4lil - hDNAP small subunit + UTP
- 6r4s - hDNAP small subunit + ATP
- 6r5e, 6r5d, 6r4u, 6r4t - hDNAP small subunit + nucleoside analog
- 5f0s, 5f0q – hDNAP large subunit C terminal + RNA
- 4bpw - hDNAP small (mutant) + large subunit + UTP
- 4bpx - hDNAP small (mutant) + DNA polymerase α catalytic subunit
- 5exr - hDNAP small + large subunits + DNA polymerase α catalytic subunit
- 8d96 - hDNAP large subunit + DNA polymerase α catalytic subunit + DNA - Cryo EM
- 8d0k 8d9d - hDNAP small + large subunits + CST + DNA polymerase α catalytic subunit + DNA – Cryo EM
- 7u5c, 8d0b - hDNAP small + large subunits + CST + DNA polymerase α catalytic+B subunits + DNA – Cryo EM
- 7opl - hDNAP small + large subunits + Nsp1 + DNA polymerase α catalytic+B subunits – Cryo EM
- 7tl3, 7tl4 – yDNAP large subunit C terminal (mutant)
- 8foc, 8fod, 8foe, 8foh, 8foj, 8fok - yDNAP small + large subunits + DNA polymerase α catalytic+B subunits – Cryo EM
- 8g99 - fDNAP large subunit + DNA polymerase α catalytic+B subunits – frog - Cryo EM
- 8ucv - fDNAP large subunit + DNA polymerase α catalytic subunit + DNA - Cryo EM
- 8g9f - fDNAP small+large subunits + DNA polymerase α catalytic subunit + DNA - Cryo EM
- 8g9o - fDNAP large subunit + DNA polymerase α catalytic+B subunits + DNA - Cryo EM
- 8g9l - fDNAP large subunit + DNA polymerase α catalytic+B subunits + DNA + RNA - Cryo EM
- 4lil - hDNAP small subunit + UTP
- Bacterial DNA primase
- 1d0q - GsDNAP zinc-binding domain - Geobacillus stearothermophilus
- 1z8s - GsdnaG dnaB binding domain - NMR
- 2haj - EcdnaG catalytic domain - NMR
- 1t3w – EcdnaG C-terminal
- 1eqn, 1dd9, 1dde – EcdnaG catalytic core
- 5w33 - MtudnaG RPD 112-432
- 5z51 - MtudnaG helicase-binding domain 482-637
- 5vaz – PadnaG
- 4im9 – VcdnaG C-terminal
- 3m1m – DNAP RNA polymerase domain – Sulfolobus islandicus
- 1zt2, 2pa8, 2pmz, 3hkz, 5ofn - SsDNAP small + large subunit – Sulfolobus solfataricus
- 2au3 – DNAP zinc-binding and RNAP domains – Aquifex aeolicus
- 1v33 - PhDNAP small subunit – Pyrocuccus horikoshii
- 1g71 - PfDNAP small subunit
- 4e2k – SaDNAP – Staphylococcus aureus
- 7ola, 7om0 – SaDNAP – Cryo EM
- 2lzn – SaDNAP C terminal – NMR
- 5guj – BsdnaG RNAP domain
- 6gt7 – SiDNAP PRN1 helix bundle domain – Sulfolobus islandicus - NMR
- 6gvu – SiDNAP PRN1 helix bundle domain + DNA - NMR
- 6gvq, 6gvt – SiDNAP PRN1 helix bundle domain + DNA + ATP - NMR
- 1d0q - GsDNAP zinc-binding domain - Geobacillus stearothermophilus
- Bacterial DNA primase complex
- 2r6a, 2r6c - GsdnaG helicase binding domain + helicase
- 4m4w - GsdnaG helicase binding domain + helicase + DnaI
- 3b39 – EcdnaG catalytic domain + DNA
- 7t22, 9eco – EcdnaG C-terminal (mutant) + helicase + DNA – Cryo EM
- 5w36, 5w35, 5w34 - MtudnaG + DNA
- 1v34 - PhDNAP small subunit + UTP
- 4edg, 4edk, 4edr, 4edt, 4edv, 4ee1 – SaDNAP + nucleotide
- 5of3 - SsDNAP small + large subunit + protein
- 7uy8 - DNAP small + large subunits + DNA polymerase α catalytic+B subunits – Tetrahymena thermophile - Cryo EM
- 2r6a, 2r6c - GsdnaG helicase binding domain + helicase
- Phage DNA primase
- 6a9w, 6k9b - NrsDNAP N terminal 1-305 – Nitratiruptor phage Nrs
- 6k9c, 6k9e, 6lrb - NrsDNAP C terminal 305-718
- 6jon, 6jop, 6joq, 6k9a - NrsDNAP N terminal + nucleotide
- 8dwj – T4DNAP + RNA + DNA – Escherichia phage T4 – Cryo EM
- 8dvf, 8dvi, 8dw6 – T4DNAP + helicase + DNA – Cryo EM
- 8gao – T4DNAP + helicase + DNA + RNA – Cryo EM
- 6a9w, 6k9b - NrsDNAP N terminal 1-305 – Nitratiruptor phage Nrs
- RNA polymerase from Bacteriophage T7 or DNA primase/helicase or GP4
- 1q57 – T7DNAP/helicase (mutant) – Enterobacteria phage T7
- 1nui – T7DNAP/helicase primase fragment (mutant)
- 1cr0 - T7DNAP/helicase helicase domain
- 1cr1, 1cr2, 1cr4 - T7DNAP/helicase helicase domain + nucleotide
- 4rnp – T7RNAP
- 1aro – T7RNAP + T7 lysozyme
- 1cez, 1h38, 1qln, 2pi4, 2pi5 - T7RNAP + DNA
- 6n7v, 6n7t, 6n7s, 6n7n, 6n7i - T7RNAP (mutant) + DNA + TTP – Cryo EM
- 1msw, 1s0v, 1s76, 1s77, 3e2e, 3e3j, 8dh0, 8dh1, 8dh2, 8dh3, 8dh4, 8dh5 - T7RNAP in elongation complex
- 6n9x, 6n9w, 6n9v, 6n9u - T7RNAP (mutant) + GP5 + DNA + RNA – Cryo EM
- 5ikn - T7RNAP (mutant) + GP5 + thioredoxin
- 1q57 – T7DNAP/helicase (mutant) – Enterobacteria phage T7
- RNA-dependent RNAP or cap-snatching endonuclease
- 7roz – AtRNAP 2 – Cryo EM
- 3phu, 1khv, 1khw – HfRNAP L RNA-directed – Hemorrhagic fever virus
- 5v5i, 5v5h, 5v5g – HfRNAP L + ubiquitin
- 2xwh, 2xxd, 2xhu,2xhw, 3i5k, 1c2p, 1csj, 1quv, 1yuy, 1yv2, 1yvx, 1yvz, 3gsz, 4aep, 4aex, 2wrm, 3mwv, 3mww – HvRNAP Ns5b domain – Hepatitis virus
- 3vc8 - HvRNAP cytoplasmic domain C terminal
- 3vcb, 4ry4, 4ry5, 4ry6, 4ry7 - HvRNAP cytoplasmic domain C terminal (mutant)
- 2xym, 2xhv, 2xi2, 4e76, 4adp, 4obc, 4wt9 - HvRNAP Ns5b domain (mutant)
- 1rdr - PoRNAP – Polio virus
- 1tql, 2ijd, 2ijf, 4nlo, 4nlp, 4nlq, 4nlr, 4nls, 4nlt, 4nlu, 4nlv, 4nlw, 4nlx, 4nly, 4r0e - PoRNAP (mutant)
- 2xi5, 2xi7 – BvRNAP L N-terminal – Bunyavirus
- 7x6s – LcvRNAP L– Lymphocytic choriomengitis virus - Cryo EM
- 3jsb – LcvRNAP L (mutant)
- 2wk4, 2uut, 2uuw – SvRNAP (mutant) – Sapporo virus
- 2ckw - SvRNAP residues 1135-1649
- 3nky, 4wyl, 4wyw, 6gvv - FmRNAP (mutant) - Foot-and-mouth virus
- 1hhs, 4a8o, 4b02, 1hi8, 5fj6 – P6RNAP – Bacteriophage φ-6
- 7ogp, 7ogr – RNAP – Bacteriophage φ-kz – Cryo EM
- 7s00, 7um1 – AR9RNAP – Bacteriophage AR9 – Cryo EM
- 7s01, 7um0 – AR9RNAP + DNA – Cryo EM
- 2jl9, 2jlf, 1wac – P6RNAP (mutant)
- 5fj7 – P6RNAP + major inner protein P1
- 2po4 – N4RNAP polymerase domain – Bacteriophage N4
- 1l9k – DevRNAP N terminal – Dengue virus
- 2j7u, 4c11 - DevRNAP polymerase domain
- 5ccv - DevRNAP NS5
- 1oks – RNAP α subunit – Measles virus
- 1r4g - RNAP α subunit – Sendai virus – NMR
- 1s48, 1s49, 1s4f – DvRNAP residues 71-679 – Diarrhea virus
- 2cjq - DvRNAP polymerase domain
- 1sh0, 1sh2, 1sh3 - NvRNAP C terminal – Norwalk virus
- 1vyi - RNAP α subunit C terminal – Rabies virus
- 2hcn, 2hcs, 2hfz – RNAP polymerase domain – West Nile virus
- 2pgg, 2pus – RNAP – Bursal disease virus
- 2r7o, 2r7q – SrRNAP – Simian rotavirus
- 4au6 - RNAP – bovine rotavirus – Cryo-EM
- 2yi8, 2yi9, 2yia, 2yib – IpnvRNAP – Infectious pancreatic necrosis virus
- 3n6l – EvRNAP – Human enterovirus
- 4uci, 4ucj, 4ucl, 4ucy, 4ucz – HmpvRNAP L residues 1600-2005 – Human metapneumovirus
- 4uck, 4ud0 – HmpvRNAP L residues 1600-2005 (mutant)
- 4zp8, 4zp9, 4zpa, 4zpb, 4zpc, 4zpd – CvRNAP residues 1724-2185 (mutant) – Coxsackievirus
- 3ddk – CvRNAP residues 1724-2185
- 3nah, 3nai, 3qid, 3uqs – MnvRNAP – Murine norovirus
- 4wfx, 4wfy, 4wfz – CvRNAP RdrP domain (mutant)
- 2j7n, 2j7o – NcRNAP residues 381-1402 – Neurospora crassa
- 4gzk, 4ieg – RNAP – cystovirus 12
- 4i1t – RNAP L – Pichinde virus
- 5chs – VsivRNAP L N-terminal – Vescicular stomatitis Indiana virus
- 4xha, 4xhi, 7om2, 7om9 – TavRNAP RdRP – Thosea asigna virus
- 6l42 – RNAP L – Phlebovirus – Cryo EM
- 6l4r – RNAP – Enterovirus
- 6ntv – SftvRNAP – Severe fever with thrombocytopenia virus – Cryo EM
- 6ntv – SftvRNAP endonuclease domain 1-226
- 6lkx – RNAP – Porcine respiratory virus
- 6kld, 7vh2, 7vh3 – MavRNAP L – Machupo virus – Cryo EM
- 6klc, 7och, 7oe3, 7oe7 – LvRNAP L – Lassa virus – Cryo EM
- 4miw, 5izh, 5j1n, 5j1p – LvRNAP L N terminal
- 4mtp, 7d6n – EnvRNAP RdrP module – Encephalitis virus
- 4cgx, 4chc – TvRNAP N terminal – Thogoto virus
- 4chd – TvRNAP 627 domain
- 4che, 4chf – TvRNAP cap-binding domain
- 5fsw - RNAP C terminal – Thielavia terrestris
- 6q99 – RNAP – Andes virus
- 5ize – HavRNAP L – Hantaan virus
- 8c4s – HavRNAP L – Cryo EM
- 5ltf – LcmvRNAP L – Lymphocytic choriomeningitis mammarenavirus
- 5lts - LcmvRNAP (mutant)
- 5u0c, 6ld1 - ZvRNAP NS5 polymerase domain 2781-3419 – Zika virus
- 6qw5, 6qw0, 6qvv - RNAP – Toscana virus
- 6dx5 - RNAP OTU domain – Farallon virus
- 6dx3 - RNAP OTU domain – Taggert virus
- 6dx2 - RNAP OTU domain – Dera Ghazi khan virus
- 6dx1, 6dwx - RNAP OTU domain – Qulybus virus
- 7eei – RNAP (mutant) – Rift valley fever virus – Cryo EM
- 7roz – AtRNAP 2 – Cryo EM
- RNA-dependent RNAP complex with RNA
- 4e78, 4e7a, 4wta, 4wtc, 4wtd, 4wte, 4wtf, 4wtg, 4wti, 4wtj, 4wtk, 4wtl, 4wtm - HvRNAP Ns5b domain (mutant) + RNA
- 3ol6, 2jlg, 4k4s, 4k4t, 4k4u, 4k4v, 4k4w – PoRNAP (mutant) + RNA
- 3ol7, 3ol8, 3ol9, 3ola, 3olb - PoRNAP (mutant) + RNA + nucleotide
- 1wne – FmRNAP + RNA
- 3klv, 3kmq, 3kms, 3kna, 3nl0, 3nma, 4iqx, 4wzm, 4wzq, 4x2b, 5jxs – FmRNAP (mutant) + RNA
- 3koa - FmRNAP (mutant) + RNA + nucleotide
- 2e9r, 2e9t, 2e9z, 2ec0 - FmRNAP + RNA + inhibitor
- 1uvi, 1uvl, 1uvm, 1uvn, 4a8f, 4a8k, 4a8m, 4a8q, 4a8s, 4a8w, 4a8y – P6RNAP + RNA
- 3bsn, 3bso, 3h5x, 3h5y - NvRNAP + RNA + nucleotide
- 2r7r, 2r7s, 2r7t, 2r7u, 2r7v, 2r7w, 2r7x – SrRNAP + RNA
- 5amq, 5amr – BvRNAP + RNA
- 7ork, 7orl, 7orj, 7orm – BvRNAP + RNA – Cryo EM
- 4k50 – RNAP + RNA – Human rhinovirus
- 3c2p, 3c3l, 3c46, 3q0a - N4RNAP polymerase domain + promoter DNA
- 1hht, 1hi0 – P6RNAP + DNA
- 1uvj, 1uvk – P6RNAP + RNA
- 4k4x, 4k4y, 4k4z – CvRNAP + RNA
- 6ogz – RvaRNAP + RNA – Rotavirus A – Cryo EM
- 6kwq – EvRNAP + RNA
- 6kwr – EvRNAP + RNA + CMP + CTP
- 6kle, 6klh – MvRNAP L + RNA – Cryo EM
- 6z6g, 6z8k – RNAP L + RNA – La crosse orthobunyavirus - Cryo EM
- 8ci5 – RNAP L + RNA – sin nombre orthohantavirus - Cryo EM
- 7y7q – NcRNAP + RNA + GTP
- 7y7p – NcRNAP + RNA + AMPNPP
- 7y7r – NcRNAP + RNA + DNA + GTP
- 7ela, 7oea, 7oeb, 7ojj, 7ojk, 7ojl, 7ojn – LvRNAP + RNA – Cryo EM
- 8c4t, 8c4u, 8c4v – HavRNAP L + RNA – Cryo EM
- 8as6, 8as7, 8asb, 8asd, 8asg – RNAP L + RNA – SFTS virus - Cryo EM
- 7om7, 7oma – TavRNAP RdrP domain + RNA
- 4e78, 4e7a, 4wta, 4wtc, 4wtd, 4wte, 4wtf, 4wtg, 4wti, 4wtj, 4wtk, 4wtl, 4wtm - HvRNAP Ns5b domain (mutant) + RNA
- RNA-dependent RNAP complex with protein
- 3phw, 2pt2, 3pt2 – HfRNAP + ubiquitin
- 3phx, 3pse – HfRNAP + ISG15
- 6u5o – HmpvRNAP L + phosphoprotein – Cryo EM
- 8fpj – HmpvRNAP L + MRK-1 – Cryo EM
- 6pzk, 6uen, 8fpi, 8fu3 – RNAP L + phosphoprotein – Human respiratory syncytial virus - Cryo EM
- 6v85, 6v86 – RNAP L + phosphoprotein – Parainfluenza virus
- 6po2, 6pns – RNAP + VP3 – Bluetongue virus - Cryo EM
- 2d7s, 2f8e, 8c1n – FmRNAP + VPG
- 8c2p – FmRNAP + protein 3B-3
- 5y3d – MnvRNAP + VPG
- 3cdw - CvRNAP + POP + VPG
- 4f5x – SrRNAP + Vp2 + Vp6
- 3zed – IpnvRNAP + capsid protein Vp3
- 6u1x – VsivRNAP + phosphoprotein
- 4hxd – RNAP L + polyubiquitin-C – Dugbe virus
- 4r71 – RNAP b chain + EF-TS EF-TU + RPS1 – Enterobacteria phage qbeta
- 5jze – RNAP + ISG15 – Erve virus
- 6tz0, 6ty8 – BmcpvRNAP + Vp4 – Bombyx mori cytoplasmic polyhedrosis virus – Cryo EM
- 6tz2, 6tz1, 6ty9, 5h0r – BmcpvRNAP + Vp4 – RNA – Cryo EM
- 6ogy – RvARNAP + Vp2 + RNA – Cryo EM
- 6k32 – RvARNAP + Vp1 + Vp4 + RNA – Cypovirus 1 - Cryo EM
- 6oar, 6oat – RNAP OUT domain + ISG17 – Kupe virus
- 7yer, 7yes, 8jsl, 8jsm, 8jsn – EbvRNAP + Vp35 – Ebola virus – Cryo EM
- 7yet – EbvRNAP + Vp35+ drug – Cryo EM
- 7ckl, 7ckm, 7elb, 7vgq, 7vh1 – MavRNAP L + matrix protein Z – Cryo EM
- 7el9, 7elc – MavRNAP L + matrix protein Z + RNA – Cryo EM
- 7x6v – LcvRNAP L + matrix protein Z – Cryo EM
- 7eju – RNAP L + matrix protein Z – Junin virus - Cryo EM
- 7yot, 7yov, 7you – RNAP + P protein – Newcastle disease virus – Cryo EM
- 3phw, 2pt2, 3pt2 – HfRNAP + ubiquitin
- RNA-dependent RNAP from SARS-COV2”
- 7btf, 7bw4 – SCRNAP + non-structural proteins – SARS-COV-2 - Cryo EM
- 6xqb, 7bzf, 7c2k, 7uo7, 7uo9, 7uob, 7uoe, 8gwb, 8gwe – SCRNAP + non-structural proteins + RNA - Cryo EM
- 7aap, 7b38, 7b3c, 7ctt, 7d4f, 7dfg, 7dfh, 7doi, 7dok, 7l1f, 7p35, 7uo4 – SCRNAP + non-structural proteins + RNA + drug - Cryo EM
- 7ed5, 8gwn, 8gwo – SCRNAP + non-structural proteins + RNA + inhibitor - Cryo EM
- 7krn, 7rdx, 7rdy, 7rdz, 7re0, 7re1, 7re2, 7re3 – SCRNAP + non-structural proteins + RNA + helicase - Cryo EM
- 7cxm, 7cxn, 7cyq – SCRNAP 4393-5324 (mutant)+ non-structural proteins + RNA + helicase - Cryo EM
- 7oyg – SCRNAP + non-structural proteins + RNA + PP1AB - Cryo EM
- 8gy6 – SCRNAP + non-structural proteins + RNA + toxin - Cryo EM
- 8gwf, 8gwg – SCRNAP + non-structural proteins + RNA + helicase + inhibitor - Cryo EM
- 7eiz – SCRNAP + non-structural proteins + RNA + methyltransferase + exoribonuclease - Cryo EM
- 7btf, 7bw4 – SCRNAP + non-structural proteins – SARS-COV-2 - Cryo EM
- RNA-dependent RNAP complex with small molecule
- 2xwy, 3mf5, 3hkw, 3hky, 3lkh, 3gnv, 3gnw, 3h98, 3g86, 3h59, 1nhu, 1nhv, 2brk, 2brl, 2gc8, 2giq, 2gir, 2hai, 2hwh, 2hwi, 2i1r, 2ijn, 2jc0, 2jc1, 2qe2, 2qe5, 2wcx, 2who, 3ciz, 3cj0, 3cj2, 3cj3, 3cj4, 3cj5, 3cso, 3cvk, 3fqk, 3fql, 3gol, 3h5s, 3h5u, 3q0z, 3qgd, 3qge, 3qgf, 3qgg, 3qgh, 3qgi, 3ska, 3ske, 3skh, 3uph, 3upi, 4dru, 3vqs, 3udl, 4eo6, 4eo8, 4eaw, 4gmc, 4ih5, 4ih6, 4ih7, 4iz0, 4jtz, 4jtw, 4jty, 4ju1, 4ju2, 4jjs, 4jju, 4j02, 4j04, 4j06, 4j08, 2yoj, 3tuq, 3tuv, 3u4o, 3u4r, 4mk7, 4mk8, 4mk9, 4mka, 4mkb, 4mz4, 4nld, 3tyq, 3tyv, 4mia, 4mib, 4oow, 4tlr, 5pzk, 5pzl, 5pzm, 5pzn, 5pzo, 5pzp, 5trh, 5tri, 5trj - HvRNAP Ns5b domain + inhibitor
- 3gyn, 1os5, 3br9, 3bsa, 3bsc, 3cde, 3co9, 3cwj, 3d28, 3d5m, 3e51, 3frz, 3igv, 3hvo, 3h2l, 4kai, 4kb7, 4kbi, 4ke5, 4khm, 4khr, 5twm, 5twn - HvRNAP Ns5b domain (mutant) + inhibitor
- 2xi3 - HvRNAP Ns5b domain (mutant) + GTP
- 1gx5, 1gx6 - HvRNAP Ns5b domain + nucleotide
- 2im1, 2im0, 2im2, 2im3, 2ily, 2ilz - PoRNAP (mutant) + nucleotide
- 3n6m, 3n6n – EvRNAP + nucleotide
- 3sfg – MnvRNAP + thio-uridine
- 3sfu – MnvRNAP + ribavirine
- 3upf, 3ur0, 4nru, 4o4r – MnvRNAP + inhibitor
- 4lq3, 4lq9 – RNAP + inhibitor – human norovirus
- 3cdu– CvRNAP + POP
- 3eva, 3evb, 3evc, 3evd, 3eve, 3evf, 3evg – RNAP N terminal + SAH – Yellow fever virus
- 1hi1 – P6RNAP + NTP
- 5cx6, 5cyr - TavRNAP + nucleotide
- 5hmw, 5f3t, 5hmx, 5hmy, 5hn0, 5hmz, 5iq6, 5k5m, 6xd0, 6xd1 - DevRNAP Ns5 + inhibitor
- 5ehg - DevRNAP NS5 + SAM + inhibitor
- 5goz, 5gp1 - ZvRNAP NS5 + SAH + GTP
- 6ld2, 6ld3, 6ld4, 6ld5 - ZvRNAP NS5 polymerase domain + inhibitor
- 5ltn, 5t2t - LcmvRNAP + inhibitor
- 6mvo – RNAP (mutant) + inhibitor – Hepacivirus C
- 6xya – SftvRNAP cap-binding domain 1695-1810 + GTP
- 8gwi – SCRNAP + inhibitor - Cryo EM
- 2xwy, 3mf5, 3hkw, 3hky, 3lkh, 3gnv, 3gnw, 3h98, 3g86, 3h59, 1nhu, 1nhv, 2brk, 2brl, 2gc8, 2giq, 2gir, 2hai, 2hwh, 2hwi, 2i1r, 2ijn, 2jc0, 2jc1, 2qe2, 2qe5, 2wcx, 2who, 3ciz, 3cj0, 3cj2, 3cj3, 3cj4, 3cj5, 3cso, 3cvk, 3fqk, 3fql, 3gol, 3h5s, 3h5u, 3q0z, 3qgd, 3qge, 3qgf, 3qgg, 3qgh, 3qgi, 3ska, 3ske, 3skh, 3uph, 3upi, 4dru, 3vqs, 3udl, 4eo6, 4eo8, 4eaw, 4gmc, 4ih5, 4ih6, 4ih7, 4iz0, 4jtz, 4jtw, 4jty, 4ju1, 4ju2, 4jjs, 4jju, 4j02, 4j04, 4j06, 4j08, 2yoj, 3tuq, 3tuv, 3u4o, 3u4r, 4mk7, 4mk8, 4mk9, 4mka, 4mkb, 4mz4, 4nld, 3tyq, 3tyv, 4mia, 4mib, 4oow, 4tlr, 5pzk, 5pzl, 5pzm, 5pzn, 5pzo, 5pzp, 5trh, 5tri, 5trj - HvRNAP Ns5b domain + inhibitor
- Influenza virus polymerase acidic protein (or PA or subunit P2) N terminal 1-256; C-terminal 257-716
- 2w69, 3ebj, 4p9a, 4nfz, 4avq, 4e5e, 4zqq, 5jht, 5jhv, 5des, 7xgc - IvRNAP PA N terminal – Influenza virus
- 5d2o, 5czn, 3hw6, 6fsb - IvRNAP PA N terminal (mutant)
- 3hw3, 3hw4, 3hw5 - IvRNAP PA residues N-terminal (mutant) + Mn + nucleotide
- 4w9s, 5fdd, 5fdg, 5i13, 5ieq, 5if2, 5if5, 5if7, 5if8, 5ifb, 5ifc, 5ifd, 5wa6, 5wa7, 5wb3, 5wap, 5w9g, 5w92, 5w44, 5v0u, 6nem, 6nel, 6e6x, 6e6w, 6e6v, 6dcz, 6dcy, 5ega, 5cl0, 5cgv, 5ccy, 4mk5, 4mk2, 4mk1, 4awm, 4awk, 4awh, 4awg, 4awf, 4e5f, 4e5g, 4e5h, 4e5i, 4e5j, 4e5l, 4yyl, 4zhz, 4zi0, 6fs7, 6fs6, 6fs8, 4avl, 4avg, 6yem, 7mty, 7mx0, 7n55, 7n68, 7v04, 8ctf – IvRNAP PA N terminal + inhibitor
- 5wg9, 5wfz, 5wfw, 5wfm, 5wf3, 5wei, 5wef, 5web, 5we9, 5we7, 5wdw, 5wdn, 5wdc, 5wct, 5wcs, 5w73, 5w7u, 5w3i, 5vrj, 5vqn, 5vpx, 5vpt, 5vp8, 6e4c, 6e3p, 6e3o, 6e3n, 6e3m, 6e0q, 6dzq, 5deb, 5dbs, 5d9j, 5d8u, 5d4g, 5d42, 6fs9, 7ml8, 7rkp – IvRNAP PA N terminal (mutant) + inhibitor
- 4iuj - IvRNAP PA C-terminal
- 7zpy – IvRNAP PA C terminal + inhibitor
- 2w69, 3ebj, 4p9a, 4nfz, 4avq, 4e5e, 4zqq, 5jht, 5jhv, 5des, 7xgc - IvRNAP PA N terminal – Influenza virus
- Influenza virus polymerase basic protein 2 (or RNAP subunit P3 or PB2)); Domains: cap-binding 318-483; Cap-binding and midlink 247-536; 627 538-693; NLS 694-753
- 4enf, 4u6o, 4j2r, 2vqz, 5ef9, 5eg9 – IvRNAP PB2 cap-binding domain
- 3wi0 – IvRNAP PB2 cap-binding domain (mutant)
- 7as2, 7as3 – IvRNAP PB2 cap-binding domain (mutant) + VX
- 7nft – IvRNAP PB2 cap-binding domain + nanobody
- 3cw4 - IvRNAP PB2 627 + NLS domains
- 2gmo - IvRNAP PB2 627 + NLS domains - NMR
- 4eqk, 5efa, 5efc – IvRNAP PB2 cap-binding domain + GTP
- 4nce, 3wi1 – IvRNAP PB2 cap-binding domain (mutant) + GTP derivative
- 4p1u, 4yd0, 5buh, 5jun, 5jur, 7as0, 7xme - IvRNAP PB2 cap-binding domain + inhibitor
- 4ncm, 7as1 – IvRNAP PB2 cap-binding domain (mutant) + inhibitor
- 6euy, 6eux, 6euv - IvRNAP PB2 cap-binding + midlink domains + inhibitor
- 5wl0 - IvRNAP PB2 cap-binding + midlink + 627 + NLS domains + inhibitor
- 4uad, 4uae, 4uaf - IvRNAP PB2 + importin
- 2vy6 - IvRNAP PB2 627 + NLS domains
- 2vy7 - IvRNAP PB2 627 domain
- 2vy8 - IvRNAP PB2 627 domain (mutant)
- 4enf, 4u6o, 4j2r, 2vqz, 5ef9, 5eg9 – IvRNAP PB2 cap-binding domain
- Influenza virus RNAP PA+PB1
- Influenza virus RNAP PA+PB2
- Influenza virus RNAP PB1+PB2
- Influenza virus RNAP PB1+P2+P3
- 7zpm - IvRNAP PB1+P2+P3 – Cryo EM
- 7nha, 7nhc, 7nhx, 7zpl, 8h69 - IvRNAP PB1+P2+P3 + RNA – Cryo EM
- 7ni0, 7nik, 7nil, 7nir, 7nis, 7nj3, 7nj4, 7nj5, 7nj7, 7nk1, 7nk2, 7nk4, 7nk6, 7nk8, 7nka, 7nkc, 7nki, 7nkr - IvRNAP PB1+P2+P3 + RNA + nanobody – Cryo EM
- 7qtl, 7r0e, 7r1f, 8bdr, 8be0, 8bek, 8bf5 - IvRNAP PB1+P2+P3 + RNA + mRNA – Cryo EM
- 7z42 - IvRNAP PB1+P2+P3 + RNA + RPB1 peptide – Cryo EM
- 7zpm - IvRNAP PB1+P2+P3 – Cryo EM
- Influenza virus RNAP PA+PB1+PB2 (subunits P1+p2+p3)
- 6qpf, 6qnw, 5d98, 5d9a - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2
- 6kv5 - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 – Cryo EM
- 4wsb, 5fmz, 5m3h, 5m3j, 5msg, 6f5o, 6evj, 6qcx, 6qcw, 6fhi, 4wrt, 4wsa - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + RNA
- 6rr7, 6qx8, 6qwl, 6qct, 6qcs, 6kuv, 6kuu, 6kut, 6kur, 6kup, 6kuk, 6kuj - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + RNA – Cryo EM
- 6qpg - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + RNA + nanobody
- 6qxe, 6qx3 - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + RNA + nanobody – Cryo EM
- 6evk - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + RNA + GTP
- 6qcv - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + RNA + CTP
- 6f5p - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + polyAla
- 6fhh - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + POL II peptide
- 6qpf, 6qnw, 5d98, 5d9a - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2
- Poly(A) RNA polymerase see Poly(A) RNA polymerase
