SARS-CoV-2 protein NSP6
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Model Confidence:
Very high (pLDDT > 90) Confident (90 > pLDDT > 70) Low (70 > pLDDT > 50) Very low (pLDDT < 50) AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions below 50 pLDDT may be unstructured in isolation.
To the right is an AlphaFold2 3D model of SARS CoV-2 Protein NSP6 (length = 290 amino acids, NCBI ID YP_009725302) color coded by the pLDDT scores. It corresponds to the highest ranked model in terms of the pLDDT confidence scores, i.e., model 3[1]. FunctionNon-structural protein 6 (nsp6) Plays a role in the initial induction of autophagosomes from host reticulum endoplasmic. Later, limits the expansion of these phagosomes that are no longer able to deliver viral components to lysosomes[1][2][3]. DiseaseRelevanceStructural highlights![]()
See alsoCoronavirus_Disease 2019 (COVID-19)
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This page was last modified 13:49, 14 February 2022.