Severin

spinqualitylabelsall models Severin domain 2 complex with Ca+2 (green) and Na+ (purple) ions 1svy Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Severin is a calcium-activated protein which binds actin. It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well. Ca coordination site. Water molecules are shown as red spheres. Na coordination site.

3D Structures of Severin

Updated on 19-November-2023

3fg6 – Adseverin C-terminal – human
1svy – DdSeverin domain 2 – Dictyostelium discoideum
1svq, 1svr - DdSeverin domain 2 - NMR

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Alexander Berchansky, Jaime Prilusky, Michal Harel