Sulfurtransferase

spinqualitylabelsall models Human mercaptopyruvate sulfurtransferase with mercaptocysteine complex with pyruvate, sulfate (PDB entry 4jgt) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Sulfurtransferase (ST) are enzymes which transfer sulfur-containing groups. Thiosulfate ST (TST) catalyzes the conversion of thiosulfate and cyanide to sulfite and thiocyanate. Mercaptopyruvate ST (MST) transfers sulfate from mercaptopyruvate. Relevance Inhibitors of MST suppress H2S production and this make non sulfur bacteria like E. coli and Bacillus anthracis sensitive to antibiotics. Structural highlights The active site of MST contains mercaptocysteine and pyruvate. Water molecules are shown as red spheres.

3D Structures of sulfurtransferase

Updated on 01-March-2024

{"openlevels":0}

• Sulfurtransferase
  • 1boh, 1boi, 1orb, 1rhd, 1rhs – bST – bovine
    
  • 1dp2 – bST + lipoate
    
  • 3lvj, 3lvk – EcST TusA + cysteine desulfurase - Escherichia coli
    
  • 2fsx – MtST – Mycobacterium tuberculosis
    
  • 1uar – ST – Thermus thermophilus
    
  • 6ktx, 6h99 – ClST – Chlorobium limicola
    
  • 6ku1, 6ku2, 6kw0 – ClST (mutant) + ergothioneine
    
  • 6h9a, 6ktv, 6ktw – ClST + hercynine
    
  • 6kvz, 6kvy, 6kvw, 6ktz – ClST (mutant) + hercynine
    
  • 7syb – ST – Acinetobacter baumanni
    
• Mercaptopyruvate sulfurtransferase
  • 3olh, 4jgt – MST - human
    
  • 5wqj, 5wqk – MST (mutant) + inhibitor – mouse
    
  • 1okg – MST (mutant) – Leishmania major
  • 1urh – EcMST
  • 5wqj, 5wqk – MST + inhibitor - mouse
    
• Thiosulfate sulfurtransferase or rhodanese
  • 6bev – hTST D1
    
  • 2ora, 8q5z – bTST
    
  • 3utn – yTST Tum1 – yeast
    
  • 6k6r – yTST Rdl2
    
  • 1yt8 – TST – Pseudomonas aeruginosa
    
  • 3hwi, 3p3a – MtTST
    
  • 3hzu – MtTST Ssea
    
  • 1e0c – AvST – Azotobacter vinelandii
    
  • 1gmx, 1gn0 – EcST Glpe
    
• Zinc-dependent sulfurtransferase SufU
  • 6jzv, 6jzw – BsZST + Zn – Bacillus subtilis
    
  • 5xt5 – BsZST + Zn + PLP
    
  • 5xt6 – BsZST + cysteine desulferase + Zn + PLP derivative
    
  • 1h4k – AvZST + hypophosphite
  • 1h4m – AvZST + phosphate

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman