Talin

spinqualitylabelsall models Talin rod domain residues 1359-1659 (PDB code 2x0c) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Talin is involved in cell-cell contacts. It links integrins to actin. It contains a C-terminal rod domain with integrin binding sites (IBS) and actin binding sites (ABS) and N-terminal FERM domain with subdomains F1-F3. The F3 subdomain interacts with integrin. Talin contains 3 Vinculin binding sites VBS1-VBS3.

3D Structures of Talin

Vinculin

References

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Alexander Berchansky, Joel L. Sussman, Michal Harel