Trehalulose synthase

spinqualitylabelsall models Structure of trehalulose synthase complex with sucrose and Ca+2 ion (green) (PDB code 2pwe). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Trehalulose synthase or sucrose isomerase (THS) converts sucrose to trehalulose (TH). Relevance Since TH is a sugar substitute and is absorbed more slowly than sucrose it can be used in diabetic and sports food and drinks. Structural highlights THS binds sucrose (water molecules are shown as red spheres) in a deep pocket with mostly conserved residues.

3D structures of trehalulose synthase

Updated on 16-December-2020

{"openlevels":0}

• Trehalulose synthase
  • 1zja, 1zjb, 2pwh – PmTHS – Pseudomonas mesoacidophila
    
  • 4go9, 4go8 – PmTHS (mutant)
    
  • 4h2c, 4h8h – RhTHS (mutant) - Rhizobium
    
  • 3gbd – PrTHS – Protaminobacter rubrum
    
  • 4how – ErTHS – Erwinia rhapontici
    
• Trehalulose synthase complex
  • 2pwd, 2pwg – PmTHS + inhibitor
    
  • 2pwe – PmTHS (mutant) + sucrose
    
  • 2pwf – PmTHS (mutant) + glucose
    
  • 4hoz – ErTHS + glucose
    
  • 4hph – ErTHS + sucrose
    
  • 4gi6, 4h7v – RhTHS (mutant) + glucose
    
  • 4gi8 – RhTHS (mutant) + sucrose
    
  • 4h8v – RhTHS + TH
    
  • 4gi9 – RhTHS (mutant) + TH
    
  • 4h8u – RhTHS (mutant) + sucrose + TH
    
  • 4gia, 4ha1 – RhTHS (mutant) + isomaltulose
    
  • 4gin – RhTHS (mutant) + inhibitor
    
  • 3gbe – PrTHS + inhibitor
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky