Trypsin inhibitor

spinqualitylabelsall models Squash seed trypsin inhibitor structure (deepskyblue) complex with trypsin (magenta) and Ca+2 ion (green) (PDB code 2sta). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Trypsin inhibitors (TI) inhibit the enzymatic activity of serine proteases and thus have nutritional effect. TI natural sources are bovine, ovomucoid, soybean, lima bean and other plants. Kunitz-type TI are found in legume seeds. Kunitz-type miraculin-like proteins are part of the soybean TI . Bowman-Birk-type TI are found in legume and cereal grains seeds. See also Basic Pancreatic Trypsin Inhibitor. Relevance The TI ulinastatin is used for the initial treatment of Kawasaki disease. Structural highlights The binding loop of TI forms multiple contacts with trypsin. Water molecules are shown as red spheres. Ca coordination site. 3D Structures of trypsin inhibitor Trypsin inhibitor 3D structures

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