Proteopedia - User contributions [en]

Laccase

2010-10-10T13:03:31Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1w6l]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>:
a <scene name='CotA_laccase/Mononuclear_t1copper/1'>mononuclear blue type 1 copper center</scene> and <scene name='CotA_laccase/Copper_centers/7'>a trinuclear center</scene>

The trinuclear center has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-10-10T10:47:06Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1w6l]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>:
a mononuclear blue type 1 copper center and <scene name='CotA_laccase/Copper_centers/7'>a trinuclear center</scene>

The trinuclear center has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-10-08T14:28:23Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1w6l]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>:
a mononuclear blue type 1 copper center and <scene name='CotA_laccase/Copper_centers/7'>a trinuclear center</scene>

#<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>
##<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers_measurements/2'>Metal Binding</scene>

The trinuclear center has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-10-08T14:16:59Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1w6l]] comprises three cupredoxin domain and four copper ions organised in #<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>:
a mononuclear blue type 1 copper center and <scene name='CotA_laccase/Copper_centers/7'>a trinuclear center</scene>

#<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>
##<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers_measurements/2'>Metal Binding</scene>

The trinuclear center has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-10-08T14:13:58Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1w6l]] comprises three cupredoxin domain and four copper ions organised in #<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>:
a mononuclear blue type 1 copper center and scene name='CotA_laccase/Copper_centers/5'>a trinuclear center</scene>.

#<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>
##<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers_measurements/2'>Metal Binding</scene>

The trinuclear center has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-10-08T14:11:19Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1w6l]] comprises three cupredoxin domain and four copper ions organised in #<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>:
a mononuclear blue type 1 copper centre and #<scene name='CotA_laccase/Copper_centers/5'>a trinuclear centre</scene>.

#<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>
##<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers_measurements/2'>Metal Binding</scene>

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-10-08T14:09:37Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1w6l]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

#<scene name='CotA_laccase/Copper_centers/5'>Two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers/4'>Two Copper Centers</scene>
#<scene name='CotA_laccase/Copper_centers_measurements/2'>Metal Binding</scene>

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-10-08T14:08:25Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1w6l]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

#<scene name='CotA_laccase/Copper_centers/5'>TextToBeDisplayed</scene>
#<scene name='CotA_laccase/Copper_centers/4'>Two Copper Centers</scene>
#<scene name='CotA_laccase/Copper_centers_measurements/2'>Metal Binding</scene>

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Sandbox Reserved 20

2010-10-08T13:56:06Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Sandbox_Reserved_20/Copper-centers/1'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 20

2010-10-08T13:55:15Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Sandbox_Reserved_20/Copper-centers/1'>TextToBeDisplayed</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved BioCrys

2010-10-07T14:10:38Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}
<ref>PMID:16234932</ref>
<references/>

Template:Sandbox Reserved BioCrys

2010-10-07T14:09:52Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}
<ref>PMID:16234932</ref>

Sandbox Reserved 20

2010-10-07T14:01:52Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 19

2010-10-07T14:01:15Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 18

2010-10-07T14:00:55Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 17

2010-10-07T14:00:23Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 16

2010-10-07T13:59:35Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 15

2010-10-07T13:59:11Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 14

2010-10-07T13:58:42Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 13

2010-10-07T13:58:13Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 12

2010-10-07T13:57:10Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 11

2010-10-07T13:56:04Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 10

2010-10-07T13:55:35Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 9

2010-10-07T13:55:10Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 8

2010-10-07T13:54:45Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 7

2010-10-07T13:54:15Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Sandbox Reserved 6

2010-10-07T13:53:41Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved BioCrys

2010-10-07T13:29:19Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/5'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved BioCrys

2010-10-07T13:28:06Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <green link='Template:Sandbox_Reserved_BioCrys/Metal_centers/3'>TextToBeDisplayed</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved BioCrys

2010-10-07T13:24:38Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/3'>TextToBeDisplayed</scene>
* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved Eric Martz 3

2010-10-07T13:22:19Z

Isabel Bento:

{| style="background-color:#ffffe0;" border="1" cellpadding="5"
| This Sandbox is Reserved from May 25, 2010, through July 31, 2010 for use in the workshops ''Practical Protein 3D Structure Visualization & Structural Bioinformatics'' taught by [[User:Eric Martz|Eric Martz]] at the University of Massachusetts, Amherst, USA. This reservation includes '''Sandbox Reserved 101''' through '''Sandbox Reserved 150'''. See [http://workshops.molviz.org Workshops.MolviZ.Org].
|-
| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.
* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol.
* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
* Add a description of your scene. Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]<applet load='Insert PDB code or filename here' size='300' frame='true' align='right' caption='Insert caption here' />
|}

Template:Sandbox Reserved BioCrys

2010-10-07T10:15:26Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/1'>green link</scene>

* Add a description of your scene.-Ex. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" -
Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved BioCrys

2010-10-07T10:14:59Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/1'>green link</scene>

* Add a description of your scene. " CotA laccase from ''Bacillus subtilis'' with two '''copper centers'''" - Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved BioCrys

2010-10-07T10:13:03Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/1'>green link</scene>

* Add a description of your scene. Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved BioCrys

2010-10-07T10:10:08Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/1'>green link</scene>

* Add a description of your scene. Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

<applet load='2ix1' size='300' frame='true' align='left' caption='Insert caption here' />

Template:Sandbox Reserved BioCrys

2010-10-07T10:09:27Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/1'>green link</scene>

* Add a description of your scene. Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

<applet load='2ix1' size='300' frame='true' align='right' caption='Insert caption here' />

Template:Sandbox Reserved BioCrys

2010-10-07T10:09:08Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/1'>green link</scene>

* Add a description of your scene. Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

<applet load='2ax0' size='300' frame='true' align='right' caption='Insert caption here' />

Template:Sandbox Reserved BioCrys

2010-10-07T10:07:01Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
Click here to see what can be achieved <scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/1'>green link</scene>

* Add a description of your scene. Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved BioCrys

2010-10-07T10:03:23Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol, similar to the one below.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
<scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/1'>green link</scene>

* Add a description of your scene. Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved BioCrys

2010-10-07T10:01:13Z

Isabel Bento:

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.

* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol.
<applet load='1w6l' size='300' frame='true' align='right' caption='Insert caption here' />

* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
<scene name='Template:Sandbox_Reserved_BioCrys/Metal_centers/1'>green link</scene>

* Add a description of your scene. Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Template:Sandbox Reserved BioCrys

2010-10-07T08:44:04Z

Isabel Bento: New page: | To get started: * Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again. * Click the '''3D''' button (when editing, abov...

| To get started:
* Click the ''edit this page'' tab at the top. Save the page after each step, then edit it again.
* Click the '''3D''' button (when editing, above the wikitext box) to insert Jmol.
* '''show''' the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
* Add a description of your scene. Use the buttons above the wikitext box for''' bold''', ''italics'', [[#|links]], <big><big>headlines</big></big>, etc.
More help: [[Help:Editing]]
|}

Laccase

2010-06-08T16:30:14Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1W6L]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

#<scene name='CotA_laccase/Copper_centers/2'>two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers/4'>two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers_measurements/2'>TextToBeDisplayed</scene>

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-06-08T16:27:49Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1W6L]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

#<scene name='CotA_laccase/Copper_centers/2'>two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers_measurements/1'>TextToBeDisplayed</scene>

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-06-08T16:27:16Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1W6L]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

#<scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers/2'>two copper centers</scene>
#<scene name='CotA_laccase/Copper_centers_measurements/1'>TextToBeDisplayed</scene>

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-06-08T16:24:48Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1W6L]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

*<scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>
*<scene name='CotA_laccase/Copper_centers/2'>two copper centers</scene>
*<scene name='CotA_laccase/Copper_centers_measurements/1'>TextToBeDisplayed</scene>

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-06-08T16:24:19Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1W6L]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

<scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>
<scene name='CotA_laccase/Copper_centers/2'>two copper centers</scene>
<scene name='CotA_laccase/Copper_centers_measurements/1'>TextToBeDisplayed</scene>

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-06-08T16:17:41Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1W6L]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/3'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-06-08T15:49:13Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1W6L]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/2'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-06-07T15:49:59Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1W6L]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/1'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.

Laccase

2010-06-07T15:49:38Z

Isabel Bento:

== CotA laccase ==
<applet load='1W6L' size='300' frame='true' align='right' caption='Insert caption here' />

CotA laccase belong to the multi-copper oxidase family.
The multi-copper oxidases constitute a family of enzymes whose
principal members are laccase (benzenediol oxygen oxidoreductase,
EC 1.10.3.2), ascorbate oxidase (L-ascorbate oxygen
oxidoreductase, EC 1.10.3.3) and ceruloplasmin (Fe(II) oxygen
oxidoreductase, EC 1.16.3.1). Similar to the other laccases the three dimensional struture of CotA [[1W6L]] comprises three cupredoxin domain and four copper ions organised in <scene name='CotA_laccase/Copper_centers/1'>two copper centers</scene>:
a mononuclear blue type 1 copper centre and a trinuclear centre.

<scene name='CotA_laccase/Copper_centers/1'>TextToBeDisplayed</scene>

The trinuclear centre has two type 3 copper ions, that can be anti-ferromagnetically
coupled through an hydroxyl moiety in between them, and one
type 2 copper ion.‡ The mononuclear copper is able to accept an
electron froma variety of phenolic substrates and then transmits
it to the trinuclear centre.