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	<id>https://proteopedia.org/api.php?action=feedcontributions&amp;feedformat=atom&amp;user=J.D.+Woodruff</id>
	<title>Proteopedia - User contributions [en]</title>
	<link rel="self" type="application/atom+xml" href="https://proteopedia.org/api.php?action=feedcontributions&amp;feedformat=atom&amp;user=J.D.+Woodruff"/>
	<link rel="alternate" type="text/html" href="https://proteopedia.org/Special:Contributions/J.D._Woodruff"/>
	<updated>2026-10-01T04:08:21Z</updated>
	<subtitle>User contributions</subtitle>
	<generator>MediaWiki 1.43.8</generator>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1131822</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1131822"/>
		<updated>2010-10-06T13:08:09Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Atp/1&#039;&amp;gt;ATP&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/H-bond/1&#039;&amp;gt;H-Bond Interaction Asp594 and PLX4032&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Superposition3og71uwh/1&#039;&amp;gt;Superposition&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Confirmation_change_dfg-in/1&#039;&amp;gt;Confirmation Change DFG-In&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Confirmation_change_dfg-out/1&#039;&amp;gt;Confirmation Change DFG-Out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1131818</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1131818"/>
		<updated>2010-10-06T13:06:07Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Atp/1&#039;&amp;gt;ATP&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/H-bond/1&#039;&amp;gt;H-Bond Interaction Asp594 and PLX4032&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Superposition3og71uwh/1&#039;&amp;gt;Superposition&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Confirmation_change_dfg-in/1&#039;&amp;gt;Confirmation Change DFG-In&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1131814</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1131814"/>
		<updated>2010-10-06T12:59:05Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Atp/1&#039;&amp;gt;ATP&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/H-bond/1&#039;&amp;gt;H-Bond Interaction Asp594 and PLX4032&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Superposition3og71uwh/1&#039;&amp;gt;Superposition&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Confirmation_change_dfg-in/1&#039;&amp;gt;TextToBeDisplayed&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1130218</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1130218"/>
		<updated>2010-10-05T19:06:14Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Atp/1&#039;&amp;gt;ATP&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/H-bond/1&#039;&amp;gt;H-Bond Interaction Asp594 and PLX4032&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Superposition3og71uwh/1&#039;&amp;gt;Superposition&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1129919</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1129919"/>
		<updated>2010-10-05T02:31:26Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Atp/1&#039;&amp;gt;ATP&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/H-bond/1&#039;&amp;gt;H-Bond Interaction Asp594 and PLX4032&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;600&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;left&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;600&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;right&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1129918</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1129918"/>
		<updated>2010-10-05T02:31:04Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Atp/1&#039;&amp;gt;ATP&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/H-bond/1&#039;&amp;gt;H-Bond Interaction Asp594 and PLX4032&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;600&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;left&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;600&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;right&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1129917</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1129917"/>
		<updated>2010-10-05T02:29:25Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/H-bond/1&#039;&amp;gt;H-Bond Interaction Asp594 and PLX4032&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;600&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;left&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Atp/1&#039;&amp;gt;TextToBeDisplayed&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;600&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;right&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=Sandbox_85&amp;diff=1129909</id>
		<title>Sandbox 85</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=Sandbox_85&amp;diff=1129909"/>
		<updated>2010-10-05T02:11:05Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;table style=&amp;quot;background-color:#ffffc0&amp;quot; cellpadding=&amp;quot;8&amp;quot; width=&amp;quot;95%&amp;quot; border=&amp;quot;0&amp;quot;&amp;gt;&amp;lt;tr&amp;gt;&amp;lt;td&amp;gt;Please do NOT make changes to this Sandbox until after December 15, 2009. Sandboxes 85-115 are reserved until then for use by the Biochemistry 451 class at Capital University taught by Prof. Jens Hemmingsen (jhemming@capital.edu).&amp;lt;/td&amp;gt;&amp;lt;/tr&amp;gt;&lt;br /&gt;
&lt;br /&gt;
This is &#039;&#039;&#039;myoglobin&#039;&#039;&#039;.&lt;br /&gt;
&lt;br /&gt;
{{STRUCTURE_1a6m |  PDB=1a6m  |  SCENE=Sandbox_85/Myoglobin_overview/3 }}&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Myoglobin_overview/3&#039;&amp;gt;Original View&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Secondary_structure/2&#039;&amp;gt;Secondary Structure&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Heme_closeup/1&#039;&amp;gt;Heme closeup&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Heme_closeup/2&#039;&amp;gt;Iron ligands&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Helixes/1&#039;&amp;gt;Pink Helixes&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Heme_zoomed/1&#039;&amp;gt;Heme Only&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Plx_4032/1&#039;&amp;gt;JD needs this&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;3og7/Superposition/5&#039;&amp;gt;Overall superposition of LepA and EF-G.&amp;lt;/scene&amp;gt; &amp;lt;small&amp;gt;Note that the individual domains of &amp;lt;font color = &#039;lime&#039;&amp;gt;&#039;&#039;&#039;LepA&#039;&#039;&#039;&amp;lt;/font&amp;gt; and &amp;lt;font color = &#039;mediumpurple&#039;&amp;gt;&#039;&#039;&#039;EF-G&#039;&#039;&#039;&amp;lt;/font&amp;gt;, such as III V, superimpose much better when done separately (shown in [http://www.pnas.org/content/105/12/4673/F2.expansion.html figure 2] of [http://www.pnas.org/content/105/12/4673.long the paper] describing the structure).&amp;lt;/small&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;applet load=&#039;1a6m&#039; size=&#039;500&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;right&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=Sandbox_85&amp;diff=1129908</id>
		<title>Sandbox 85</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=Sandbox_85&amp;diff=1129908"/>
		<updated>2010-10-05T02:10:25Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;table style=&amp;quot;background-color:#ffffc0&amp;quot; cellpadding=&amp;quot;8&amp;quot; width=&amp;quot;95%&amp;quot; border=&amp;quot;0&amp;quot;&amp;gt;&amp;lt;tr&amp;gt;&amp;lt;td&amp;gt;Please do NOT make changes to this Sandbox until after December 15, 2009. Sandboxes 85-115 are reserved until then for use by the Biochemistry 451 class at Capital University taught by Prof. Jens Hemmingsen (jhemming@capital.edu).&amp;lt;/td&amp;gt;&amp;lt;/tr&amp;gt;&lt;br /&gt;
&lt;br /&gt;
This is &#039;&#039;&#039;myoglobin&#039;&#039;&#039;.&lt;br /&gt;
&lt;br /&gt;
{{STRUCTURE_1a6m |  PDB=1a6m  |  SCENE=Sandbox_85/Myoglobin_overview/3 }}&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Myoglobin_overview/3&#039;&amp;gt;Original View&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Secondary_structure/2&#039;&amp;gt;Secondary Structure&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Heme_closeup/1&#039;&amp;gt;Heme closeup&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Heme_closeup/2&#039;&amp;gt;Iron ligands&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Helixes/1&#039;&amp;gt;Pink Helixes&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Heme_zoomed/1&#039;&amp;gt;Heme Only&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;Sandbox_85/Plx_4032/1&#039;&amp;gt;JD needs this&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;3cb4/Superposition/5&#039;&amp;gt;Overall superposition of LepA and EF-G.&amp;lt;/scene&amp;gt; &amp;lt;small&amp;gt;Note that the individual domains of &amp;lt;font color = &#039;lime&#039;&amp;gt;&#039;&#039;&#039;LepA&#039;&#039;&#039;&amp;lt;/font&amp;gt; and &amp;lt;font color = &#039;mediumpurple&#039;&amp;gt;&#039;&#039;&#039;EF-G&#039;&#039;&#039;&amp;lt;/font&amp;gt;, such as III V, superimpose much better when done separately (shown in [http://www.pnas.org/content/105/12/4673/F2.expansion.html figure 2] of [http://www.pnas.org/content/105/12/4673.long the paper] describing the structure).&amp;lt;/small&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;applet load=&#039;1a6m&#039; size=&#039;500&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;right&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1129139</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1129139"/>
		<updated>2010-09-30T17:34:10Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/H-bond/1&#039;&amp;gt;H-Bond Interaction Asp594 and PLX4032&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;600&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;left&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;600&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;right&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1129138</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1129138"/>
		<updated>2010-09-30T17:30:15Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/H-bond/1&#039;&amp;gt;H-Bond Interaction Asp594 and PLX4032&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;600&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;left&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;600&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;right&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127628</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127628"/>
		<updated>2010-09-29T02:30:04Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/H-bond/1&#039;&amp;gt;H-Bond Interaction Asp594 and PLX4032&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127621</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127621"/>
		<updated>2010-09-29T01:50:52Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;Wild-Type B-RAF&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;V600E Mutation&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127619</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127619"/>
		<updated>2010-09-29T01:49:43Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Wild-type_b-raf/1&#039;&amp;gt;TextToBeDisplayed&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;TextToBeDisplayed&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/V600e_mutation/1&#039;&amp;gt;V600E mutation&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127618</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127618"/>
		<updated>2010-09-29T01:42:50Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Mutated_v600e/1&#039;&amp;gt;TextToBeDisplayed&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/V600e_mutation/1&#039;&amp;gt;V600E mutation&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127617</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127617"/>
		<updated>2010-09-29T01:37:16Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/V600e_mutation/1&#039;&amp;gt;V600E mutation&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;PLX4032 Sulfonamide N&amp;lt;/scene&amp;gt; &amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127616</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127616"/>
		<updated>2010-09-29T01:35:41Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/V600e_mutation/1&#039;&amp;gt;V600E mutation&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx4032_n/1&#039;&amp;gt;TextToBeDisplayed&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127615</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127615"/>
		<updated>2010-09-29T01:17:53Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/V600e_mutation/1&#039;&amp;gt;V600E mutation&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127614</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127614"/>
		<updated>2010-09-29T01:17:21Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF. &lt;br /&gt;
&lt;br /&gt;
Replace the PDB id (use lowercase!) after the STRUCTURE_ and after PDB= to load &lt;br /&gt;
and display another structure.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/V600e_mutation/1&#039;&amp;gt;V600E mutation&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
	<entry>
		<id>https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127613</id>
		<title>B-RAF with PLX4032</title>
		<link rel="alternate" type="text/html" href="https://proteopedia.org/index.php?title=B-RAF_with_PLX4032&amp;diff=1127613"/>
		<updated>2010-09-29T01:14:05Z</updated>

		<summary type="html">&lt;p&gt;J.D. Woodruff: &lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;==B-RAF with PLX4032==&lt;br /&gt;
This is a placeholder text to help you get started in &lt;br /&gt;
placing a Jmol applet on your page. At any time, click&lt;br /&gt;
&amp;quot;Show Preview&amp;quot; at the bottom of this page to see how it goes.&lt;br /&gt;
&lt;br /&gt;
Replace the PDB id (use lowercase!) after the STRUCTURE_ and after PDB= to load &lt;br /&gt;
and display another structure.&lt;br /&gt;
&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Plx_4032_only/1&#039;&amp;gt;PLX 4032&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/V600e_mutation/1&#039;&amp;gt;V600E mutation&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Dfg_in_conformation/1&#039;&amp;gt;DFG in&amp;lt;/scene&amp;gt;&amp;lt;br&amp;gt;&lt;br /&gt;
&amp;lt;scene name=&#039;B-RAF_with_PLX4032/Phe_595_dfg_out/1&#039;&amp;gt;DFG out&amp;lt;/scene&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;3og7&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;br /&gt;
&amp;lt;applet load=&#039;1uwh&#039; size=&#039;700&#039; color=&#039;white&#039; frame=&#039;true&#039; align=&#039;center&#039; caption=&#039;testcaption&#039; /&amp;gt;&lt;/div&gt;</summary>
		<author><name>J.D. Woodruff</name></author>
	</entry>
</feed>