https://proteopedia.org/api.php?action=feedcontributions&feedformat=atom&user=Nachum+NathanProteopedia - User contributions [en]2026-09-20T23:37:00ZUser contributionsMediaWiki 1.43.8https://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40603571U6A (Hebrew)2024-02-20T09:48:22Z<p>Nachum Nathan: </p>
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<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='300' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.[http://www.9gag.com 9GAG]<br />
My refrence [[1u6a]]<br />
my reference_2 [http://www.9gag.com 9GAG]<br />
DOI ref <ref> </ref><br />
</p.<br />
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== Function ==<br />
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== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40603551U6A (Hebrew)2024-02-20T09:47:39Z<p>Nachum Nathan: </p>
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<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='300' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.[http://www.9gag.com 9GAG]<br />
My refrence [[1u6a]]<br />
my reference_2 [http://www.9gag.com 9GAG]<br />
DOI ref <ref><br />
</p.<br />
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== Function ==<br />
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== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
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<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40603531U6A (Hebrew)2024-02-20T09:46:59Z<p>Nachum Nathan: </p>
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<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.[http://www.9gag.com 9GAG]<br />
My refrence [[1u6a]]<br />
my reference_2 [http://www.9gag.com 9GAG]<br />
DOI ref <ref><br />
</p.<br />
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== Function ==<br />
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== Disease ==<br />
</StructureSection><br />
== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40603501U6A (Hebrew)2024-02-20T09:45:36Z<p>Nachum Nathan: </p>
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<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.[http://www.9gag.com 9GAG]<br />
My refrence [[1u6a]]<br />
my reference_2 [http://www.9gag.com 9GAG]<br />
DOI ref <ref><br />
</p.<br />
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== Function ==<br />
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== Disease ==<br />
</StructureSection><br />
== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
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<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40603471U6A (Hebrew)2024-02-20T09:44:24Z<p>Nachum Nathan: </p>
<hr />
<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.[http://www.9gag.com 9GAG]<br />
My refrence [[1u6a]]<br />
my reference_2 [http://www.9gag.com 9GAG]<br />
DOI ref <ref> <br />
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== Function ==<br />
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== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
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== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40603441U6A (Hebrew)2024-02-20T09:43:06Z<p>Nachum Nathan: </p>
<hr />
<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.[http://www.9gag.com 9GAG]<br />
My refrence [[1u6a]]<br />
my reference_2 [http://www.9gag.com 9GAG]<br />
DOI ref <ref> <br />
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== Function ==<br />
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== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40603291U6A (Hebrew)2024-02-20T09:35:20Z<p>Nachum Nathan: </p>
<hr />
<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.[http://www.9gag.com 9GAG]<br />
My refrence [[1u6a]]<br />
my reference_2 [http://www.9gag.com 9GAG]<br />
DOI ref <ref> <br />
<br />
== Function ==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
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<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40602791U6A (Hebrew)2024-02-20T09:03:57Z<p>Nachum Nathan: </p>
<hr />
<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.[http://www.9gag.com 9GAG]<br />
My refrence [[1u6a]]<br />
my reference_2 [http://www.9gag.com 9GAG]<br />
DOI ref<nowiki>Insert non-formatted text here</nowiki><br />
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== Function ==<br />
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== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40602741U6A (Hebrew)2024-02-20T08:57:54Z<p>Nachum Nathan: </p>
<hr />
<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.[http://www.9gag.com 9GAG]<br />
My refrence [[1u6a]]<br />
my reference_2 [http://www.9gag.com 9GAG]<br />
<br />
== Function ==<br />
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== Disease ==<br />
<br />
== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40602721U6A (Hebrew)2024-02-20T08:56:10Z<p>Nachum Nathan: </p>
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<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
My refrence [[1u6a]]<br />
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== Function ==<br />
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== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
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<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40602711U6A (Hebrew)2024-02-20T08:54:54Z<p>Nachum Nathan: </p>
<hr />
<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
My refrence [[Mice]]<br />
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== Function ==<br />
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== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40602351U6A (Hebrew)2024-02-20T08:37:41Z<p>Nachum Nathan: </p>
<hr />
<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
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== Function ==<br />
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== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
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<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40602331U6A (Hebrew)2024-02-20T08:35:25Z<p>Nachum Nathan: </p>
<hr />
<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='3HI1' size='340' side='right' caption='נוגדן' scene=''><br />
<br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Function ==<br />
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== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=1U6A_(Hebrew)&diff=40602191U6A (Hebrew)2024-02-20T08:23:40Z<p>Nachum Nathan: New page: ==<center>'''נוגדן נגד HIV'''</center>== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> This is a default text for your page '...</p>
<hr />
<div>==<center>'''נוגדן נגד HIV'''</center>==<br />
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''1U6A (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
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== Function ==<br />
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== Disease ==<br />
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== Relevance ==<br />
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== Structural highlights ==<br />
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
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</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060194BCL6 (Hebrew)2024-02-20T08:00:23Z<p>Nachum Nathan: </p>
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<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
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== Intorduction ==<br />
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<!-- This is a comment --><br />
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Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
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== Exploring the Structure ==<br />
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GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
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== Function ==<br />
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== Structural highlights ==<br />
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
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==מבנה ותפקוד האנזים==<br />
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<br><br />
בעת פעולתו, האנזים RT מועד לטעויות. בניסוי<ref>Preston, B., Poiesz, B., & Loeb, L. (1988). Fidelity of HIV-1 Reverse Transcriptase. Science, 242(4882), 1168-1171. Retrieved from http://www.jstor.org/stable/1702640</ref> שנערך נמצא כי תדירות המוטציות במולקולת ה-DNA הנוצרת הוא 1 ל-4000-2000. <br />
<br><br />
משמעות הדבר היא שמתרחשת מוטציה אחת כל כשלושת אלפים נוקלאוטידים המתרכבים למולקולת ה-DNA הנוצרת. קצב המוטציות הגבוה גורם לכך שהחומר התורשתי של הנגיף משתנה כמעט עם כל הדבקה. עקב כך, מוטציות שמתרחשות במהלך פעולתו של אנזים RT גורמות לשינוי החומר הגנטי של הנגיף. דבר זה מאפשר לנגיף "להתחמק" מן המערכת החיסונית של המאכסן ולפתח עמידות נגד תרופות אנטי-ויראליות, ולכן פיתוח תרופות נגד הנגיף נתקל בקשיים רבים.<br />
<br><br />
<br><br />
</p><br />
<br />
<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==שאלון==<br />
<br />
<quiz display=simple><br />
{מה אתם חושבים על ה<scene name="/12/3456/Sample/1">סצנה</scene>?}<br />
- סבבה<br />
- לא משהוא<br />
+ וואו איזה מגניב!<br />
- אינפורמטיבי<br />
</quiz><br />
<br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060193BCL6 (Hebrew)2024-02-20T07:59:42Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<br />
<br />
<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
<br />
<br />
<p dir='rtl'><br />
<br />
<br><br />
בעת פעולתו, האנזים RT מועד לטעויות. בניסוי<ref>Preston, B., Poiesz, B., & Loeb, L. (1988). Fidelity of HIV-1 Reverse Transcriptase. Science, 242(4882), 1168-1171. Retrieved from http://www.jstor.org/stable/1702640</ref> שנערך נמצא כי תדירות המוטציות במולקולת ה-DNA הנוצרת הוא 1 ל-4000-2000. <br />
<br><br />
משמעות הדבר היא שמתרחשת מוטציה אחת כל כשלושת אלפים נוקלאוטידים המתרכבים למולקולת ה-DNA הנוצרת. קצב המוטציות הגבוה גורם לכך שהחומר התורשתי של הנגיף משתנה כמעט עם כל הדבקה. עקב כך, מוטציות שמתרחשות במהלך פעולתו של אנזים RT גורמות לשינוי החומר הגנטי של הנגיף. דבר זה מאפשר לנגיף "להתחמק" מן המערכת החיסונית של המאכסן ולפתח עמידות נגד תרופות אנטי-ויראליות, ולכן פיתוח תרופות נגד הנגיף נתקל בקשיים רבים.<br />
<br><br />
<br><br />
</p><br />
<br />
<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==שאלון==<br />
<br />
<quiz display=simple><br />
{מה אתם חושבים על ה<scene name="/12/3456/Sample/1">סצנה</scene>?}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
</p><br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060191BCL6 (Hebrew)2024-02-20T07:58:19Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<br />
<br />
<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
<br />
<br />
<p dir='rtl'><br />
<br />
<br><br />
בעת פעולתו, האנזים RT מועד לטעויות. בניסוי<ref>Preston, B., Poiesz, B., & Loeb, L. (1988). Fidelity of HIV-1 Reverse Transcriptase. Science, 242(4882), 1168-1171. Retrieved from http://www.jstor.org/stable/1702640</ref> שנערך נמצא כי תדירות המוטציות במולקולת ה-DNA הנוצרת הוא 1 ל-4000-2000. <br />
<br><br />
משמעות הדבר היא שמתרחשת מוטציה אחת כל כשלושת אלפים נוקלאוטידים המתרכבים למולקולת ה-DNA הנוצרת. קצב המוטציות הגבוה גורם לכך שהחומר התורשתי של הנגיף משתנה כמעט עם כל הדבקה. עקב כך, מוטציות שמתרחשות במהלך פעולתו של אנזים RT גורמות לשינוי החומר הגנטי של הנגיף. דבר זה מאפשר לנגיף "להתחמק" מן המערכת החיסונית של המאכסן ולפתח עמידות נגד תרופות אנטי-ויראליות, ולכן פיתוח תרופות נגד הנגיף נתקל בקשיים רבים.<br />
<br><br />
<br><br />
</p><br />
<br />
<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==שאלון==<br />
<br />
<quiz display=simple><br />
{מה אתם חושבים על ה<br />
<scene name="/12/3456/Sample/1">סצנה</scene>?}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
</p><br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060189BCL6 (Hebrew)2024-02-20T07:57:40Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<br />
<br />
<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
<br />
<br />
<p dir='rtl'><br />
<br />
<br><br />
בעת פעולתו, האנזים RT מועד לטעויות. בניסוי<ref>Preston, B., Poiesz, B., & Loeb, L. (1988). Fidelity of HIV-1 Reverse Transcriptase. Science, 242(4882), 1168-1171. Retrieved from http://www.jstor.org/stable/1702640</ref> שנערך נמצא כי תדירות המוטציות במולקולת ה-DNA הנוצרת הוא 1 ל-4000-2000. <br />
<br><br />
משמעות הדבר היא שמתרחשת מוטציה אחת כל כשלושת אלפים נוקלאוטידים המתרכבים למולקולת ה-DNA הנוצרת. קצב המוטציות הגבוה גורם לכך שהחומר התורשתי של הנגיף משתנה כמעט עם כל הדבקה. עקב כך, מוטציות שמתרחשות במהלך פעולתו של אנזים RT גורמות לשינוי החומר הגנטי של הנגיף. דבר זה מאפשר לנגיף "להתחמק" מן המערכת החיסונית של המאכסן ולפתח עמידות נגד תרופות אנטי-ויראליות, ולכן פיתוח תרופות נגד הנגיף נתקל בקשיים רבים.<br />
<br><br />
<br><br />
</p><br />
<br />
<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==שאלון==<br />
<br />
<quiz display=simple><br />
{ <scene name="/12/3456/Sample/1">סצנה</scene>?מה אתם חושבים על ה}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
</p><br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060185BCL6 (Hebrew)2024-02-20T07:51:50Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<br />
<br />
<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
<br />
<br />
<p dir='rtl'><br />
<br />
<br><br />
בעת פעולתו, האנזים RT מועד לטעויות. בניסוי<ref>Preston, B., Poiesz, B., & Loeb, L. (1988). Fidelity of HIV-1 Reverse Transcriptase. Science, 242(4882), 1168-1171. Retrieved from http://www.jstor.org/stable/1702640</ref> שנערך נמצא כי תדירות המוטציות במולקולת ה-DNA הנוצרת הוא 1 ל-4000-2000. <br />
<br><br />
משמעות הדבר היא שמתרחשת מוטציה אחת כל כשלושת אלפים נוקלאוטידים המתרכבים למולקולת ה-DNA הנוצרת. קצב המוטציות הגבוה גורם לכך שהחומר התורשתי של הנגיף משתנה כמעט עם כל הדבקה. עקב כך, מוטציות שמתרחשות במהלך פעולתו של אנזים RT גורמות לשינוי החומר הגנטי של הנגיף. דבר זה מאפשר לנגיף "להתחמק" מן המערכת החיסונית של המאכסן ולפתח עמידות נגד תרופות אנטי-ויראליות, ולכן פיתוח תרופות נגד הנגיף נתקל בקשיים רבים.<br />
<br><br />
<br><br />
</p><br />
<br />
<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==שאלון==<br />
<br />
<quiz display=simple><br />
{What do you think about Proteopedia <scene name="/12/3456/Sample/1">color</scene>?}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
</p><br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060183BCL6 (Hebrew)2024-02-20T07:50:32Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<br />
<br />
<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
==מבנה ותפקוד האנזים==<br />
<br />
<br />
<p dir='rtl'><br />
<br />
<br><br />
בעת פעולתו, האנזים RT מועד לטעויות. בניסוי<ref>Preston, B., Poiesz, B., & Loeb, L. (1988). Fidelity of HIV-1 Reverse Transcriptase. Science, 242(4882), 1168-1171. Retrieved from http://www.jstor.org/stable/1702640</ref> שנערך נמצא כי תדירות המוטציות במולקולת ה-DNA הנוצרת הוא 1 ל-4000-2000. <br />
<br><br />
משמעות הדבר היא שמתרחשת מוטציה אחת כל כשלושת אלפים נוקלאוטידים המתרכבים למולקולת ה-DNA הנוצרת. קצב המוטציות הגבוה גורם לכך שהחומר התורשתי של הנגיף משתנה כמעט עם כל הדבקה. עקב כך, מוטציות שמתרחשות במהלך פעולתו של אנזים RT גורמות לשינוי החומר הגנטי של הנגיף. דבר זה מאפשר לנגיף "להתחמק" מן המערכת החיסונית של המאכסן ולפתח עמידות נגד תרופות אנטי-ויראליות, ולכן פיתוח תרופות נגד הנגיף נתקל בקשיים רבים.<br />
<br><br />
<br><br />
</p><br />
<br />
<br />
<br />
<p dir='rtl'><br />
==Quiz==<br />
</p><br />
<quiz display=simple><br />
{What do you think about Proteopedia <scene name="/12/3456/Sample/1">color</scene>?}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
</p><br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060181BCL6 (Hebrew)2024-02-20T07:49:27Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
<br />
<br />
==מבנה ותפקוד האנזים==<br />
<div style="text-align: right; direction: rtl; margin-left: 1em;"><br />
<br />
<p dir='rtl'><br />
<br />
<br><br />
בעת פעולתו, האנזים RT מועד לטעויות. בניסוי<ref>Preston, B., Poiesz, B., & Loeb, L. (1988). Fidelity of HIV-1 Reverse Transcriptase. Science, 242(4882), 1168-1171. Retrieved from http://www.jstor.org/stable/1702640</ref> שנערך נמצא כי תדירות המוטציות במולקולת ה-DNA הנוצרת הוא 1 ל-4000-2000. <br />
<br><br />
משמעות הדבר היא שמתרחשת מוטציה אחת כל כשלושת אלפים נוקלאוטידים המתרכבים למולקולת ה-DNA הנוצרת. קצב המוטציות הגבוה גורם לכך שהחומר התורשתי של הנגיף משתנה כמעט עם כל הדבקה. עקב כך, מוטציות שמתרחשות במהלך פעולתו של אנזים RT גורמות לשינוי החומר הגנטי של הנגיף. דבר זה מאפשר לנגיף "להתחמק" מן המערכת החיסונית של המאכסן ולפתח עמידות נגד תרופות אנטי-ויראליות, ולכן פיתוח תרופות נגד הנגיף נתקל בקשיים רבים.<br />
<br><br />
<br><br />
</p><br />
<br />
<br />
<br />
<p dir='rtl'><br />
==Quiz==<br />
</p><br />
<quiz display=simple><br />
{What do you think about Proteopedia <scene name="/12/3456/Sample/1">color</scene>?}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
</p><br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060179BCL6 (Hebrew)2024-02-20T07:48:34Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<p dir='rtl'><br />
==מהימנות הפעילות האנזימטית==<br />
</p><br />
<br />
<p dir='rtl'><br />
<br />
<br><br />
בעת פעולתו, האנזים RT מועד לטעויות. בניסוי<ref>Preston, B., Poiesz, B., & Loeb, L. (1988). Fidelity of HIV-1 Reverse Transcriptase. Science, 242(4882), 1168-1171. Retrieved from http://www.jstor.org/stable/1702640</ref> שנערך נמצא כי תדירות המוטציות במולקולת ה-DNA הנוצרת הוא 1 ל-4000-2000. <br />
<br><br />
משמעות הדבר היא שמתרחשת מוטציה אחת כל כשלושת אלפים נוקלאוטידים המתרכבים למולקולת ה-DNA הנוצרת. קצב המוטציות הגבוה גורם לכך שהחומר התורשתי של הנגיף משתנה כמעט עם כל הדבקה. עקב כך, מוטציות שמתרחשות במהלך פעולתו של אנזים RT גורמות לשינוי החומר הגנטי של הנגיף. דבר זה מאפשר לנגיף "להתחמק" מן המערכת החיסונית של המאכסן ולפתח עמידות נגד תרופות אנטי-ויראליות, ולכן פיתוח תרופות נגד הנגיף נתקל בקשיים רבים.<br />
<br><br />
<br><br />
</p><br />
<br />
<br />
<br />
<p dir='rtl'><br />
==Quiz==<br />
</p><br />
<quiz display=simple><br />
{What do you think about Proteopedia <scene name="/12/3456/Sample/1">color</scene>?}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
</p><br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060178BCL6 (Hebrew)2024-02-20T07:47:48Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<br />
==מהימנות הפעילות האנזימטית==<br />
<br />
<br />
<p dir='rtl'><br />
<br />
<br><br />
בעת פעולתו, האנזים RT מועד לטעויות. בניסוי<ref>Preston, B., Poiesz, B., & Loeb, L. (1988). Fidelity of HIV-1 Reverse Transcriptase. Science, 242(4882), 1168-1171. Retrieved from http://www.jstor.org/stable/1702640</ref> שנערך נמצא כי תדירות המוטציות במולקולת ה-DNA הנוצרת הוא 1 ל-4000-2000. <br />
<br><br />
משמעות הדבר היא שמתרחשת מוטציה אחת כל כשלושת אלפים נוקלאוטידים המתרכבים למולקולת ה-DNA הנוצרת. קצב המוטציות הגבוה גורם לכך שהחומר התורשתי של הנגיף משתנה כמעט עם כל הדבקה. עקב כך, מוטציות שמתרחשות במהלך פעולתו של אנזים RT גורמות לשינוי החומר הגנטי של הנגיף. דבר זה מאפשר לנגיף "להתחמק" מן המערכת החיסונית של המאכסן ולפתח עמידות נגד תרופות אנטי-ויראליות, ולכן פיתוח תרופות נגד הנגיף נתקל בקשיים רבים.<br />
<br><br />
<br><br />
</p><br />
<br />
<br />
<br />
<p dir='rtl'><br />
==Quiz==<br />
</p><br />
<quiz display=simple><br />
{What do you think about Proteopedia <scene name="/12/3456/Sample/1">color</scene>?}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
</p><br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060177BCL6 (Hebrew)2024-02-20T07:46:38Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<br />
<p dir='rtl'><br />
==Quiz==<br />
<quiz display=simple><br />
{What do you think about Proteopedia <scene name="/12/3456/Sample/1">color</scene>?}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
</p><br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060175BCL6 (Hebrew)2024-02-20T07:42:34Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
<br />
<br />
==Quiz==<br />
<quiz display=simple><br />
{What do you think about Proteopedia <scene name="/12/3456/Sample/1">color</scene>?}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
<br />
</StructureSection><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4060173BCL6 (Hebrew)2024-02-20T07:30:30Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
<br />
==Quiz==<br />
<quiz display=simple><br />
{What do you think about Proteopedia?}<br />
- Nice<br />
- Okay<br />
+ So cool, I can't believe I didn't know about it before!<br />
- informative<br />
</quiz><br />
<br />
<br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=Sandbox_offir&diff=4060170Sandbox offir2024-02-20T07:23:08Z<p>Nachum Nathan: </p>
<hr />
<div>===<center>''קאטלז''</center>===<br />
<br />
<Structure load='1qqw' size='400' frame='true' align='right' caption='מבנה הקאטלז'/><br />
== '''מבוא''' ==<br />
<br />
<br />
<br />
===<div style="text-align:right">'''כותרת מימין'''</div>===<br />
<br />
<p dir='rtl'><br />
<br />
קטלאז הוא אנזים המצוי כמעט בכל האורנגיזמים הנחשפים לחמצן: בעלי חיים, בצמחים, בפטריות ובמיקרואורנזימים רבים<br />
[[Image:Catalase_assay.jpg|300px]]<br />
<br />
<br><br />
באדם מצוי הקטלאז כמעט בכל תאי הגוף ואיבריו, ובכמות גדולה נמצא בכבד, בכליות ובתאי הדם<br />
</p><br />
<!-- --><br />
<p dir='rtl'><br />
מבחן קטלאז להבחנה בין מיני חיידקים: <br />
<br />
<scene name='84/845945/Amino_acid/2'>מחומצות האמינו השונות</scene> המבנה מורכב<br />
<br />
תפקידו של האנזים הוא לפרק [https://en.wikipedia.org/wiki/Hydrogen_peroxide מי חמצן] <br />
למים וחמצן. משקלו המולקולרי של החלבון השלם הוא כ - 60 קילו-דלתון<br />
לחלבון יש שרשראות <scene name='84/845945/Beta_sheets/1'>בטא</scene><br />
<br><br />
<br />
<br />
== '''מבוא''' ==<br />
== '''מבוא''' ==<br />
<br />
----<br />
<br />
''' כך כותבים בטקסט מודגש'''<br />
<br />
כך מכניסים רפרנס לטקסט <ref>PMID:8794733</ref> וממשיכים במשפט<br />
<br />
<br />
<br />
<scene name='54/547082/C--n_rainbow/3'>C ו-N</scene><br />
<br />
<scene name='54/547082/Alpha/3'>סלילי אלפא</scene><br />
<br />
<scene name='54/547082/Secondary/2'>השניוני</scene><br />
<br />
<scene name='54/547082/Hydrophobic-polar/1'>בתצוגת הליזוזים הבאה</scene><br />
<br />
<scene name='84/845945/Amino_acids/6'>חומצות אמינו</scene><br />
<br />
<br><br />
<br />
== מקורות מידע ==<br />
<br />
<br />
<br />
<references/><br />
<br />
<quiz display=simple><br />
{השאלה שלי מס'1<br />
|type="()"}<br />
+ The correct answer.<br />
- Distractor.<br />
- Distractor.<br />
- Distractor.<br />
<br />
{השאלה שלי מס'2<br />
|type="()"}<br />
- The correct answer.<br />
+ Distractor.<br />
- Distractor.<br />
- Distractor.<br />
</quizz></div>Nachum Nathanhttps://proteopedia.org/index.php?title=Sandbox_offir&diff=4060168Sandbox offir2024-02-20T07:21:27Z<p>Nachum Nathan: </p>
<hr />
<div>===<center>''קאטלז''</center>===<br />
<br />
<Structure load='1qqw' size='400' frame='true' align='right' caption='מבנה הקאטלז'/><br />
== '''מבוא''' ==<br />
<br />
<br />
<br />
===<div style="text-align:right">'''כותרת מימין'''</div>===<br />
<br />
<p dir='rtl'><br />
<br />
קטלאז הוא אנזים המצוי כמעט בכל האורנגיזמים הנחשפים לחמצן: בעלי חיים, בצמחים, בפטריות ובמיקרואורנזימים רבים<br />
[[Image:Catalase_assay.jpg|300px]]<br />
<br />
<br><br />
באדם מצוי הקטלאז כמעט בכל תאי הגוף ואיבריו, ובכמות גדולה נמצא בכבד, בכליות ובתאי הדם<br />
</p><br />
<!-- --><br />
<p dir='rtl'><br />
מבחן קטלאז להבחנה בין מיני חיידקים: <br />
<br />
<scene name='84/845945/Amino_acid/2'>מחומצות האמינו השונות</scene> המבנה מורכב<br />
<br />
תפקידו של האנזים הוא לפרק [https://en.wikipedia.org/wiki/Hydrogen_peroxide מי חמצן] <br />
למים וחמצן. משקלו המולקולרי של החלבון השלם הוא כ - 60 קילו-דלתון<br />
לחלבון יש שרשראות <scene name='84/845945/Beta_sheets/1'>בטא</scene><br />
<br><br />
<br />
<br />
== '''מבוא''' ==<br />
== '''מבוא''' ==<br />
<br />
----<br />
<br />
''' כך כותבים בטקסט מודגש'''<br />
<br />
כך מכניסים רפרנס לטקסט <ref>PMID:8794733</ref> וממשיכים במשפט<br />
<br />
<br />
<br />
<scene name='54/547082/C--n_rainbow/3'>C ו-N</scene><br />
<br />
<scene name='54/547082/Alpha/3'>סלילי אלפא</scene><br />
<br />
<scene name='54/547082/Secondary/2'>השניוני</scene><br />
<br />
<scene name='54/547082/Hydrophobic-polar/1'>בתצוגת הליזוזים הבאה</scene><br />
<br />
<scene name='84/845945/Amino_acids/6'>חומצות אמינו</scene><br />
<br />
<br><br />
<br />
== מקורות מידע ==<br />
<br />
<br />
<br />
<references/><br />
<br />
<quiz display=simple><br />
{Question<br />
|type="()"}<br />
+ The correct answer.<br />
- Distractor.<br />
- Distractor.<br />
- Distractor.<br />
<br />
{My question is- aaaaaaa?<br />
|type="()"}<br />
- The correct answer.<br />
+ Distractor.<br />
- Distractor.<br />
- Distractor.<br />
</quizz></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4048507BCL6 (Hebrew)2024-02-13T09:40:22Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<!-- This is a comment --><br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4048423BCL6 (Hebrew)2024-02-13T07:48:10Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<br />
Green fluorescent protein ('''GFP'''), originally isolated from the jellyfish Aequorea victoria (PDB entry [[1ema]]), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4048421BCL6 (Hebrew)2024-02-13T07:46:36Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
== Intorduction ==<br />
<br />
<br />
Green fluorescent protein (GFP), originally isolated from the jellyfish Aequorea victoria (PDB entry 1ema), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
<br />
== Exploring the Structure ==<br />
<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4038308BCL6 (Hebrew)2024-02-06T09:25:20Z<p>Nachum Nathan: </p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1R28' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
<br />
Green fluorescent protein (GFP), originally isolated from the jellyfish Aequorea victoria (PDB entry 1ema), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
Exploring the Structure<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=BCL6_(Hebrew)&diff=4038306BCL6 (Hebrew)2024-02-06T09:24:39Z<p>Nachum Nathan: New page: ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> This is a default text for you...</p>
<hr />
<div>==Your Heading Here (maybe something like 'Structure')==<br />
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''><br />
This is a default text for your page '''BCL6 (Hebrew)'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.<br />
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.<br />
<br />
<br />
Green fluorescent protein (GFP), originally isolated from the jellyfish Aequorea victoria (PDB entry 1ema), fluorsceses green (509nm) when exposed to blue light (395nm and 475nm). It is one of the most important proteins used in biological research because it can be used to tag otherwise invisible gene products of interest and thus observe their existence, location and movement.<br />
<br />
Exploring the Structure<br />
GFP is a beta barrel protein with 11 beta sheets. It is a 26.9kDa protein made up of 238 amino acids. The chromophore, responsible for the fluorescent properties of the protein, is buried inside the beta barrel as part of the central alpha helix passing through the barrel. The chromophore forms via spontaneous cyclization and oxidation of three residues in the central alpha helix: -Thr65 (or Ser65)-Tyr66-Gly67. This cyclization and oxidation creates the chromophore's five-membered ring via a new bond between the threonine and the glycine residues.<ref>PMID:8703075</ref><br />
<br />
== Function ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
<br />
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.<br />
<br />
</StructureSection><br />
== References ==<br />
<references/></div>Nachum Nathanhttps://proteopedia.org/index.php?title=File:Beuatiful_picture_NN.jpg&diff=4038303File:Beuatiful picture NN.jpg2024-02-06T09:20:28Z<p>Nachum Nathan: </p>
<hr />
<div></div>Nachum Nathan