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2026-09-14T09:13:28Z
User contributions
MediaWiki 1.43.8
https://proteopedia.org/index.php?title=Malic_enzyme_1&diff=2487363
Malic enzyme 1
2015-09-20T19:28:57Z
<p>PDBe: Redirecting to NADP-dependent malic enzyme</p>
<hr />
<div>#REDIRECT [[NADP-dependent_malic_enzyme]]</div>
PDBe
https://proteopedia.org/index.php?title=NADP-ME&diff=2487362
NADP-ME
2015-09-20T19:28:54Z
<p>PDBe: Redirecting to NADP-dependent malic enzyme</p>
<hr />
<div>#REDIRECT [[NADP-dependent_malic_enzyme]]</div>
PDBe
https://proteopedia.org/index.php?title=Malic_Enzyme_1&diff=2487361
Malic Enzyme 1
2015-09-20T19:15:55Z
<p>PDBe: Redirecting to NADP-dependent malic enzyme</p>
<hr />
<div>#REDIRECT [[NADP-dependent_malic_enzyme]]</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2487360
NADP-dependent malic enzyme
2015-09-20T19:05:43Z
<p>PDBe: </p>
<hr />
<div><StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: [[3wja]]' scene=''><br />
Best example is PDB entry [[3wja]] and is shown in the viewer.<br><br />
==Catalytic Activity ==<br />
Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
malate metabolic process<br><br />
oxidation-reduction process<br><br />
response to carbohydrate<br><br />
response to hormone<br><br />
carbohydrate metabolic process<br><br />
protein tetramerization<br><br />
regulation of NADP metabolic process<br><br />
NADP biosynthetic process<br><br />
small molecule metabolic process<br><br />
cellular lipid metabolic process<br><br />
== In structures ==<br />
NADP-dependent malic enzyme is found in 3 PDB entries<br><br />
*<b>Eukaryota</b> (3 PDB entries): <br><br />
**<b>Homo sapiens</b> (2 PDB entries): <br><br />
***[[3wja]] <div class="pdb-prints 3wja"></div><br />
***Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form<br />
***2.548 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22NADP-dependent%20malic%20enzyme%22&!chimera:y Search the PDB for NADP-dependent malic enzyme from Homo sapiens]<br />
**<b>Columba livia</b> (1 PDB entries): <br><br />
***[[1gq2]] <div class="pdb-prints 1gq2"></div><br />
***Title: MALIC ENZYME FROM PIGEON LIVER<br />
***2.5 A resolution<br />
== Alternative names for NADP-dependent malic enzyme ==<br />
Molecule NADP-dependent malic enzyme, also known as NADP-ME, NADP-dependent malic enzyme and Malic enzyme 1.<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Beta-secretase_1&diff=2487359
Beta-secretase 1
2015-09-20T18:58:22Z
<p>PDBe: </p>
<hr />
<div><StructureSection load='4ivt' size='340' side='right' caption='The best structure for Beta-secretase 1 shown: [[4ivt]]' scene=''><br />
Best example is PDB entry [[4ivt]] and is shown in the viewer.<br><br />
== Function ==<br />
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
==Catalytic Activity ==<br />
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
== In structures ==<br />
Beta-secretase 1 is found in 323 PDB entries<br><br />
*<b>Eukaryota</b> (323 PDB entries): <br><br />
**<b>Homo sapiens</b> (323 PDB entries): <br><br />
***[[4ivt]] <div class="pdb-prints 4ivt"></div><br />
***Title: Crystal structure of BACE1 with its inhibitor<br />
***1.6 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Beta-secretase%201%22&!chimera:y Search the PDB for Beta-secretase 1 from Homo sapiens]<br />
== Alternative names for Beta-secretase 1 ==<br />
Molecule Beta-secretase 1, also known as Beta-site amyloid precursor protein cleaving enzyme 1, Membrane-associated aspartic protease 2, Aspartyl protease 2, Asp 2, ASP2, Memapsin-2, Beta-secretase 1 and Beta-site APP cleaving enzyme 1.<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Beta-secretase_1&diff=2487358
Beta-secretase 1
2015-09-20T18:55:51Z
<p>PDBe: </p>
<hr />
<div><StructureSection load='4ivt' size='340' side='right' caption='The best structure for Beta-secretase 1 shown: [[4ivt]]' scene=''><br />
Best example is PDB entry [[4ivt]] and is shown in the viewer.<br><br />
== Function ==<br />
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
==Catalytic Activity ==<br />
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
== In structures ==<br />
Beta-secretase 1 is found in 323 PDB entries<br><br />
*<b>Eukaryota</b> (323 PDB entries): <br><br />
**<b>Homo sapiens</b> (323 PDB entries): <br><br />
***[[4ivt]] <div class="pdb-prints 4ivt"></div><br />
***Title: Crystal structure of BACE1 with its inhibitor<br />
***1.6 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Beta-secretase%201%22&!chimera:y Search the PDB for Beta-secretase 1 from Homo sapiens]<br />
== Alternative names for Beta-secretase%201 ==Molecule Beta-secretase%201, also known as Beta-site amyloid precursor protein cleaving enzyme 1, Membrane-associated aspartic protease 2, Aspartyl protease 2, Asp 2, ASP2, Memapsin-2, Beta-secretase 1 and Beta-site APP cleaving enzyme 1.<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Beta-secretase_1&diff=2487353
Beta-secretase 1
2015-09-18T20:35:06Z
<p>PDBe: </p>
<hr />
<div><StructureSection load='4ivt' size='340' side='right' caption='The best structure for Beta-secretase 1 shown: [[4ivt]]' scene=''><br />
Best example is PDB entry [[4ivt]] and is shown in the viewer.<br><br />
== Function ==<br />
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
==Catalytic Activity ==<br />
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
== In structures ==<br />
Beta-secretase 1 is found in 323 PDB entries<br><br />
*<b>Eukaryota</b> (323 PDB entries): <br><br />
**<b>Homo sapiens</b> (323 PDB entries): <br><br />
***[[4ivt]] <div class="pdb-prints 4ivt"></div><br />
***Title: Crystal structure of BACE1 with its inhibitor<br />
***1.6 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Beta-secretase%201%22&!chimera:y Search the PDB for Beta-secretase 1 from Homo sapiens]<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Beta-secretase_1&diff=2487352
Beta-secretase 1
2015-09-18T20:30:00Z
<p>PDBe: </p>
<hr />
<div><StructureSection load='4ivt' size='340' side='right' caption='The best structure for Beta-secretase 1 shown: [[4ivt]]' scene=''><br />
Best example is PDB entry [[4ivt]] and is shown in the viewer.<br><br />
Molecule Beta-secretase 1, also known as Beta-site amyloid precursor protein cleaving enzyme 1, Membrane-associated aspartic protease 2, Aspartyl protease 2, Asp 2, ASP2, Memapsin-2, Beta-secretase 1 and Beta-site APP cleaving enzyme 1.<br />
== Function ==<br />
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
==Catalytic Activity ==<br />
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
== In structures ==<br />
Beta-secretase 1 is found in 323 PDB entries<br><br />
*<b>Eukaryota</b> (323 PDB entries): <br><br />
**<b>Homo sapiens</b> (323 PDB entries): <br><br />
***[[4ivt]] <div class="pdb-prints 4ivt"></div><br />
***Title: Crystal structure of BACE1 with its inhibitor<br />
***1.6 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Beta-secretase%201%22&!chimera:y Search the PDB for Beta-secretase 1 from Homo sapiens]<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Beta-secretase_1&diff=2487351
Beta-secretase 1
2015-09-18T20:28:45Z
<p>PDBe: </p>
<hr />
<div><StructureSection load='4ivt' size='340' side='right' caption='The best structure for Beta-secretase 1 shown: [[4ivt]]' scene=''><br />
Best example is PDB entry [[4ivt]] and is shown in the viewer.<br><br />
Molecule Beta-secretase 1, also known as Beta-site amyloid precursor protein cleaving enzyme 1, Membrane-associated aspartic protease 2, Aspartyl protease 2, Asp 2, ASP2, Memapsin-2, Beta-secretase 1 and Beta-site APP cleaving enzyme 1.<br />
== Function ==<br />
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
==Catalytic Activity ==<br />
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
== In structures ==<br />
Beta-secretase 1 is found in 323 PDB entries<br><br />
*<b>Eukaryota</b> (323 PDB entries): <br><br />
**<b>Homo sapiens</b> (323 PDB entries): <br><br />
***[[4ivt]] <div class="pdb-prints 4ivt"></div><br />
***Title: Crystal structure of BACE1 with its inhibitor<br />
***1.6 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Beta-secretase%201%22&!chimera:y Search for other Beta-secretase 1 PDB entries from Homo sapiens]<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Beta-secretase_1&diff=2487350
Beta-secretase 1
2015-09-18T20:27:23Z
<p>PDBe: </p>
<hr />
<div><StructureSection load='4ivt' size='340' side='right' caption='The best structure for Beta-secretase 1 shown: [[4ivt]]' scene=''><br />
Best example is PDB entry [[4ivt]] and is shown in the viewer.<br><br />
Molecule Beta-secretase 1, also known as Beta-site amyloid precursor protein cleaving enzyme 1, Membrane-associated aspartic protease 2, Aspartyl protease 2, Asp 2, ASP2, Memapsin-2, Beta-secretase 1 and Beta-site APP cleaving enzyme 1.<br />
== Function ==<br />
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
==Catalytic Activity ==<br />
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
== In structures ==<br />
Beta-secretase 1 is found in 323 PDB entries<br><br />
*<b>Eukaryota</b> (323 PDB entries): <br><br />
**<b>Homo sapiens</b> (323 PDB entries): <br><br />
***[[4ivt]] <div class="pdb-prints 4ivt"></div><br />
***Title: Crystal structure of BACE1 with its inhibitor<br />
***1.6 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Beta-secretase%201%22&!chimera:y Search for other Beta-secretase 1 PDB entries from organism Homo sapiens]<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Beta-secretase_1&diff=2487349
Beta-secretase 1
2015-09-18T20:20:52Z
<p>PDBe: </p>
<hr />
<div><StructureSection load='4ivt' size='340' side='right' caption='The best structure for Beta-secretase 1 shown: [[4ivt]]' scene=''><br />
Best example is PDB entry [[4ivt]] and is shown in the viewer.<br><br />
Molecule Beta-secretase 1, also known as Beta-site amyloid precursor protein cleaving enzyme 1, Membrane-associated aspartic protease 2, Aspartyl protease 2, Asp 2, ASP2, Memapsin-2, Beta-secretase 1 and Beta-site APP cleaving enzyme 1.<br />
== Function ==<br />
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
==Catalytic Activity ==<br />
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
== In structures ==<br />
Beta-secretase 1 is found in 323 PDB entries<br><br />
*<b>Eukaryota</b> (323 PDB entries): <br><br />
**<b>Homo sapiens</b> (323 PDB entries): <br><br />
***[[4ivt]] <div class="pdb-prints 4ivt"></div><br />
***Title: Crystal structure of BACE1 with its inhibitor<br />
***1.6 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Beta-secretase%201%22&!chimera:y Search for other PDB entries]<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Integrase&diff=2487306
Integrase
2015-09-15T20:23:20Z
<p>PDBe: New page: <StructureSection load='3fx5' size='340' side='right' caption='The best structure for Integrase shown: 3fx5' scene=''> Best example is PDB entry 3fx5 and is shown in the viewer.<br> Mo...</p>
<hr />
<div><StructureSection load='3fx5' size='340' side='right' caption='The best structure for Integrase shown: 3fx5' scene=''><br />
Best example is PDB entry [[3fx5]] and is shown in the viewer.<br><br />
Molecule Integrase, also known as Integrase, p2B, p10, Capsid protein p27, p4, p3, Reverse transcriptase beta-subunit, Protease p15, Nucleocapsid protein p12, Reverse transcriptase alpha-subunit, RT-alpha, p2A, RT-beta, Gag-Pro-Pol polyprotein, pp32, Matrix protein p19, IN, Matrix protein p17, Transframe peptide, Reverse transcriptase/ribonuclease H, Pr160Gag-Pol, Spacer peptide 1, p2, Exoribonuclease H, p6*, Gag-Pol polyprotein, Nucleocapsid protein p7, p15, Retropepsin, p6-pol, p66 RT, Protease, PR, CA, TF, NC, SP1, Capsid protein p24, MA, p51 RT, Ribonuclease H, Protease/Reverse transcriptase, Pro-Pol polyprotein, Pr125Pol, Protease/Reverse transcriptase/ribonuclease H, RNase H, p87Pro-RT-RNaseH, p42In, p65Pro-RT, INT, Pol polyprotein, dUTPase, RT, Deoxyuridine 5'-triphosphate nucleotidohydrolase, P72, Pr170Gag-Pol, p11, p2L, Capsid protein p26, Matrix protein p16, P119, Putative prophage integrase, Int protein, CP4-like integrase, Transposase from transposon Tn916, NC-pro, Pr160Gag-Pro-Pol, Nucleocapsid protein p15-pro, p1 and NC'.<br />
== Function ==<br />
Integrase: Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions. This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA. The first step in the integration process is 3' processing. This step requires a complex comprising the viral genome, matrix protein, Vpr and integrase. This complex is called the pre-integration complex (PIC). The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends. In the second step, the PIC enters cell nucleus. This process is mediated through integrase and Vpr proteins, and allows the virus to infect a non dividing cell. This ability to enter the nucleus is specific of lentiviruses, other retroviruses cannot and rely on cell division to access cell chromosomes. In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration. The 5'-ends are produced by integrase-catalyzed staggered cuts, 5 bp apart. A Y-shaped, gapped, recombination intermediate results, with the 5'-ends of the viral DNA strands and the 3' ends of target DNA strands remaining unjoined, flanking a gap of 5 bp. The last step is viral DNA integration into host chromosome. This involves host DNA repair synthesis in which the 5 bp gaps between the unjoined strands are filled in and then ligated. Since this process occurs at both cuts flanking the HIV genome, a 5 bp duplication of host DNA is produced at the ends of HIV-1 integration. Alternatively, Integrase may catalyze the excision of viral DNA just after strand transfer, this is termed disintegration.Data source: Uniprot [http://www.uniprot.org/uniprot/P03367 P03367]<br><br />
==Catalytic Activity ==<br />
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).Data source: Uniprot [http://www.uniprot.org/uniprot/P03367 P03367]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
DNA integration<br><br />
RNA-dependent DNA replication<br><br />
viral process<br><br />
dUTP metabolic process<br><br />
DNA recombination<br><br />
establishment of integrated proviral latency<br><br />
viral entry into host cell<br><br />
== In structures ==<br />
Integrase is found in 1103 PDB entries<br><br />
*<b>Viruses</b> (1062 PDB entries): <br><br />
**<b>Human immunodeficiency virus 1</b> (550 PDB entries): <br><br />
***[[3fx5]] <div class="pdb-prints 3fx5"></div><br />
***Title: Structure of HIV-1 Protease in Complex with Potent Inhibitor KNI-272 Determined by High Resolution X-ray Crystallography<br />
***0.93 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20immunodeficiency%20virus%201%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>HIV-1 M:B_HXB2R</b> (71 PDB entries): <br><br />
***[[3kt5]] <div class="pdb-prints 3kt5"></div><br />
***Title: Crystal Structure of N88S mutant HIV-1 Protease<br />
***1.801 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22HIV-1%20M:B_HXB2R%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human immunodeficiency virus type 1 BH10</b> (69 PDB entries): <br><br />
***[[4zip]] <div class="pdb-prints 4zip"></div><br />
***Title: HIV-1 wild Type protease with GRL-0648A (a isophthalamide-derived P2-Ligand)<br />
***1.11 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20immunodeficiency%20virus%20type%201%20BH10%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)</b> (52 PDB entries): <br><br />
***[[3avj]] <div class="pdb-prints 3avj"></div><br />
***Title: Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site<br />
***1.7 A resolution<br />
***Other macromolecules also in this entry: LEDGF peptide..<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20immunodeficiency%20virus%20type%201%20(NEW%20YORK-5%20ISOLATE)%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>HIV-1 M:B_ARV2/SF2</b> (46 PDB entries): <br><br />
***[[4obj]] <div class="pdb-prints 4obj"></div><br />
***Title: Crystal Structure of Inactive HIV-1 Protease in Complex with the p1-p6 substrate variant (S451N)<br />
***1.75 A resolution<br />
***Other macromolecules also in this entry: Spacer peptide 2..<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22HIV-1%20M:B_ARV2/SF2%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human immunodeficiency virus type 1 (BRU ISOLATE)</b> (45 PDB entries): <br><br />
***[[3vf7]] <div class="pdb-prints 3vf7"></div><br />
***Title: Crystal Structure of HIV-1 Protease Mutant L76V with novel P1'-Ligands GRL-02031<br />
***1.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20immunodeficiency%20virus%20type%201%20(BRU%20ISOLATE)%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human spumaretrovirus</b> (44 PDB entries): <br><br />
***[[3oym]] <div class="pdb-prints 3oym"></div><br />
***Title: Crystal structure of the PFV N224H mutant intasome bound to manganese<br />
***2.02 A resolution<br />
***Other macromolecules also in this entry: DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3').<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20spumaretrovirus%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human immunodeficiency virus</b> (41 PDB entries): <br><br />
***[[1kzk]] <div class="pdb-prints 1kzk"></div><br />
***Title: JE-2147-HIV Protease Complex<br />
***1.09 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20immunodeficiency%20virus%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human immunodeficiency virus type 1 (Z2/CDC-Z34 ISOLATE)</b> (16 PDB entries): <br><br />
***[[2wkz]] <div class="pdb-prints 2wkz"></div><br />
***Title: HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimic with Improved Cell-Based Antiviral Activity<br />
***1.7 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20immunodeficiency%20virus%20type%201%20(Z2/CDC-Z34%20ISOLATE)%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Feline immunodeficiency virus</b> (13 PDB entries): <br><br />
***[[1fiv]] <div class="pdb-prints 1fiv"></div><br />
***Title: STRUCTURE OF AN INHIBITOR COMPLEX OF PROTEINASE FROM FELINE IMMUNODEFICIENCY VIRUS<br />
***2.0 A resolution<br />
***Other macromolecules also in this entry: FIV PROTEASE INHIBITOR ACE-ALN-VAL-STA-GLU-ALN-NH2..<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Feline%20immunodeficiency%20virus%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human immunodeficiency virus type 1 (BH5 ISOLATE)</b> (12 PDB entries): <br><br />
***[[3d20]] <div class="pdb-prints 3d20"></div><br />
***Title: Crystal structure of HIV-1 mutant I54V and inhibitor DARUNAVIA<br />
***1.05 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20immunodeficiency%20virus%20type%201%20(BH5%20ISOLATE)%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Rous sarcoma virus (strain Schmidt-Ruppin)</b> (11 PDB entries): <br><br />
***[[1a5x]] <div class="pdb-prints 1a5x"></div><br />
***Title: ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3<br />
***1.9 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Rous%20sarcoma%20virus%20(strain%20Schmidt-Ruppin)%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human immunodeficiency virus type 2 (ISOLATE ROD)</b> (8 PDB entries): <br><br />
***[[3ecg]] <div class="pdb-prints 3ecg"></div><br />
***Title: High Resolution HIV-2 Protease Structure in Complex with Antiviral Inhibitor GRL-98065<br />
***1.18 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20immunodeficiency%20virus%20type%202%20(ISOLATE%20ROD)%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Avian sarcoma virus</b> (7 PDB entries): <br><br />
***[[1czb]] <div class="pdb-prints 1czb"></div><br />
***Title: ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN FROM HEPES<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Avian%20sarcoma%20virus%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human immunodeficiency virus type 1 (CLONE 12)</b> (5 PDB entries): <br><br />
***[[1hxb]] <div class="pdb-prints 1hxb"></div><br />
***Title: HIV-1 proteinase complexed with RO 31-8959<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20immunodeficiency%20virus%20type%201%20(CLONE%2012)%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>HUMAN IMMUNODEFICIENCY VIRUS 1</b> (4 PDB entries): <br><br />
***[[2j9k]] <div class="pdb-prints 2j9k"></div><br />
***Title: Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor MVT-101<br />
***1.2 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22HUMAN%20IMMUNODEFICIENCY%20VIRUS%201%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Rous sarcoma virus - Prague C</b> (3 PDB entries): <br><br />
***[[4fw1]] <div class="pdb-prints 4fw1"></div><br />
***Title: Crystal structure of two-domain RSV INTEGRASE covalently linked with DNA<br />
***1.86 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Rous%20sarcoma%20virus%20-%20Prague%20C%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Bovine immunodeficiency virus R29</b> (2 PDB entries): <br><br />
***[[3kkr]] <div class="pdb-prints 3kkr"></div><br />
***Title: Crystal structure of catalytic core domain of BIV integrase in crystal form I<br />
***2.453 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Bovine%20immunodeficiency%20virus%20R29%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Streptomyces phage phiC31</b> (1 PDB entries): <br><br />
***[[4bqq]] <div class="pdb-prints 4bqq"></div><br />
***Title: Protein crystal structure of the N-terminal and recombinase domains of the Streptomyces temperate phage serine recombinase, fC31 integrase.<br />
***2.15 A resolution<br />
*<b>Bacteria</b> (10 PDB entries): <br><br />
**<b>Enterococcus faecalis</b> (4 PDB entries): <br><br />
***[[1bb8]] <div class="pdb-prints 1bb8"></div><br />
***Title: N-TERMINAL DNA BINDING DOMAIN FROM TN916 INTEGRASE, NMR, 25 STRUCTURES<br />
***N/A A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterococcus%20faecalis%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Yersinia pestis</b> (2 PDB entries): <br><br />
***[[3jtz]] <div class="pdb-prints 3jtz"></div><br />
***Title: Structure of the arm-type binding domain of HPI integrase<br />
***1.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Yersinia%20pestis%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
**<b>Staphylococcus aureus subsp. aureus USA300_TCH1516</b> (1 PDB entries): <br><br />
***[[3nkh]] <div class="pdb-prints 3nkh"></div><br />
***Title: Crystal Structure of Integrase from MRSA strain Staphylococcus aureus<br />
***2.502 A resolution<br />
*<b>Eukaryota</b> (3 PDB entries): <br><br />
**<b>Homo sapiens</b> (3 PDB entries): <br><br />
***[[3ufn]] <div class="pdb-prints 3ufn"></div><br />
***Title: Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20 in Complex with Saquinavir<br />
***1.45 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Integrase%22&!chimera:y Search for other PDB entries]<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=RNA-directed_RNA_polymerase&diff=2487305
RNA-directed RNA polymerase
2015-09-15T20:19:36Z
<p>PDBe: New page: <StructureSection load='4dcd' size='340' side='right' caption='The best structure for RNA-directed RNA polymerase shown: 4dcd' scene=''> Best example is PDB entry 4dcd and is shown in ...</p>
<hr />
<div><StructureSection load='4dcd' size='340' side='right' caption='The best structure for RNA-directed RNA polymerase shown: 4dcd' scene=''><br />
Best example is PDB entry [[4dcd]] and is shown in the viewer.<br><br />
Molecule RNA-directed RNA polymerase, also known as Protein P2, RNA-directed RNA polymerase, p8, NS3P, Hepacivirin, gp70, gp32, Protease NS2-3, p21, p27, NS4A, Core protein p21, Non-structural protein 4B, p23, Core protein p19, NS5A, p70, p68, NS5B, Serine protease NS3, NS1, Non-structural protein 4A, gp68, gp35, Envelope glycoprotein E1, Genome polyprotein, p56, Capsid protein C, Non-structural protein 5A, NS4B, p7, Envelope glycoprotein E2, gp55, N-pro, N-terminal protease, Non-structural protein 3, gp33, Non-structural protein 2-3, E(rns) glycoprotein, Autoprotease p20, Non-structural protein 2, gp44/48, Cysteine protease NS2, Picornain 2A, P1B, P3B, Protease 3C, 3D polymerase, Capsid protein VP1, P1D, Protein 3B, P1C, VP4-VP2, Capsid protein VP4, Protein 2B, Virion protein 3, P3A, Capsid protein VP0, 3Dpol, Virion protein 1, VPg, Protein 2C, Capsid protein VP3, P3C, Protein 2A, P1A, Virion protein 2, Viral protein genome-linked, Protein 3D, P2A, Virion protein 4, Protein 3A, 3D, Protein 3AB, Protein 3CD, P2B, P2C, RdRp, P1, Capsid protein VP2, P2, Protease 2A, P3, Protein VP1, p13, Viral genome-linked protein, Protein p18, Capsid protein VP60, NTPase, Precursor p41, p15, 3CLpro, 3C-like protease, Protein p29, Protein p16, Calicivirin, p37, Protein p23/2, Protein p23, p58, 2C-like protein, Thiol protease P3C, p254, RDRP, nsp3, p65 homolog, nsp5, 2'-O-methyltransferase, 3CLp, Uridylate-specific endoribonuclease, nsp12, pp1ab, Non-structural protein 8, Hel, Leader protein, GFL, nsp2, Host translation inhibitor nsp1, NendoU, nsp14, PL-PRO, Growth factor-like peptide, nsp16, SARS coronavirus main proteinase, Pol, ExoN, ORF1ab polyprotein, Papain-like proteinase, Non-structural protein 9, nsp4, Non-structural protein 6, Non-structural protein 10, nsp1, nsp15, nsp7, Non-structural protein 4, nsp13, nsp6, 3CL-PRO, 3C-like proteinase, Non-structural protein 7, Replicase polyprotein 1ab, nsp8, Helicase, nsp10, nsp9, PL2-PRO, Guanine-N7 methyltransferase, NS2-3, HEL, 42 kDa protein, Methyltransferase/Protease, RNA replicase polyprotein, 66 kDa protein, MET/PRO, Putative helicase, 98 kDa protein, 206 kDa polyprotein, POL, Protein L, Transcriptase, Large structural protein, Replicase, mRNA (guanine-N(7)-)-methyltransferase, mRNA guanylyltransferase, RNA-directed RNA polymerase L, PL1-PRO/PL2-PRO, Peptide HD2, p12, p66-HEL, p5, Putative 2'-O-methyl transferase, p14, p66, Non-structural protein 1, Exoribonuclease, p195, Papain-like proteinases 1/2, p34, p41, p9, M-PRO, PLP1/PLP2, p100, p87, Ubiquitin thioesterase, nsp11, Non-structural protein 11, VPG, Protein p48, Protein p22, p10, p33, p39, p16, p35, p24, 3CLSP, Non-structural protein 5-6-7, 3C-like serine proteinase, Nsp6, Nsp3, Nsp5, Non-structural protein 7-beta, Nsp4, Nsp5-6-7, Nsp9, Nsp8, Non-structural protein 12, CP2, Non-structural protein 7-alpha, Nsp7-alpha, Nsp12, CP, Nsp10, PCP, Nsp2 cysteine proteinase, Nsp7-beta, Nsp11, Nsp1 papain-like cysteine proteinase, Non-structural protein 5, Core protein, p6, Nuclear inclusion protein B, Helper component proteinase, 6 kDa protein 1, Nuclear inclusion protein A, NI-a, P1 proteinase, 49 kDa proteinase, Capsid protein, NIa-pro, CI, 6K1, NI-b, NIb, 6K2, 49 kDa-Pro, Cytoplasmic inclusion protein, 6 kDa protein 2, HC-pro, Protein P3, N-terminal protein, Coat protein, NIa, 183 kDa protein, 126 kDa protein, MT/HEL, Methyltransferase/RNA helicase, Replicase small subunit, Replicase large subunit, p22, p67, p28, p65, p44 and p210.<br />
== Function ==<br />
NS5B is an RNA-dependent RNA polymerase that plays an essential role in the virus replication.Data source: Uniprot [http://www.uniprot.org/uniprot/P26663 P26663]<br><br />
==Catalytic Activity ==<br />
ATP + H(2)O = ADP + phosphate.Data source: Uniprot [http://www.uniprot.org/uniprot/P26663 P26663]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
viral RNA genome replication<br><br />
proteolysis<br><br />
viral genome replication<br><br />
transcription, DNA-templated<br><br />
transformation of host cell by virus<br><br />
viral protein processing<br><br />
transcription, RNA-templated<br><br />
RNA-protein covalent cross-linking<br><br />
viral process<br><br />
== In structures ==<br />
RNA-directed RNA polymerase is found in 623 PDB entries<br><br />
*<b>Viruses</b> (602 PDB entries): <br><br />
**<b>Hepatitis C virus</b> (78 PDB entries): <br><br />
***[[4dgv]] <div class="pdb-prints 4dgv"></div><br />
***Title: Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody HCV1, P2(1) form<br />
***1.805 A resolution<br />
***Other macromolecules also in this entry: HCV1 Heavy Chain, HCV1 Light Chain.<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hepatitis%20C%20virus%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>SARS coronavirus</b> (57 PDB entries): <br><br />
***[[2v6n]] <div class="pdb-prints 2v6n"></div><br />
***Title: CRYSTAL STRUCTURES OF THE SARS-CORONAVIRUS MAIN PROTEINASE INACTIVATED BY BENZOTRIAZOLE COMPOUNDS<br />
***1.98 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22SARS%20coronavirus%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human poliovirus 1 Mahoney</b> (47 PDB entries): <br><br />
***[[4dcd]] <div class="pdb-prints 4dcd"></div><br />
***Title: 1.6A resolution structure of PolioVirus 3C Protease Containing a covalently bound dipeptidyl inhibitor<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20poliovirus%201%20Mahoney%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Hepatitis C virus (isolate BK)</b> (45 PDB entries): <br><br />
***[[4eo8]] <div class="pdb-prints 4eo8"></div><br />
***Title: HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres<br />
***1.798 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hepatitis%20C%20virus%20(isolate%20BK)%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Hepatitis C virus isolate HC-J4</b> (44 PDB entries): <br><br />
***[[3u4o]] <div class="pdb-prints 3u4o"></div><br />
***Title: Novel HCV NS5B polymerase Inhibitors: Discovery of Indole C2 Acyl sulfonamides<br />
***1.77 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hepatitis%20C%20virus%20isolate%20HC-J4%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human rhinovirus B14</b> (33 PDB entries): <br><br />
***[[4pdw]] <div class="pdb-prints 4pdw"></div><br />
***Title: A benzonitrile analogue inhibits rhinovirus replication<br />
***3.0 A resolution<br />
***Other macromolecules also in this entry: Capsid protein VP4/VP2, Capsid protein VP2, Capsid protein VP3, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20rhinovirus%20B14%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Hepatitis C virus subtype 1b</b> (25 PDB entries): <br><br />
***[[3ciz]] <div class="pdb-prints 3ciz"></div><br />
***Title: Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments<br />
***1.87 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hepatitis%20C%20virus%20subtype%201b%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Hepatitis C virus JFH-1</b> (20 PDB entries): <br><br />
***[[4wtm]] <div class="pdb-prints 4wtm"></div><br />
***Title: CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS IN COMPLEX WITH RNA TEMPLATE 5'-UAGG, RNA PRIMER 5'-PCC, MN2+, AND UDP<br />
***2.15 A resolution<br />
***Other macromolecules also in this entry: RNA PRIMER CC, RNA TEMPLATE UAGG.<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hepatitis%20C%20virus%20JFH-1%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Pseudomonas phage phi6</b> (19 PDB entries): <br><br />
***[[4a8o]] <div class="pdb-prints 4a8o"></div><br />
***Title: Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation<br />
***2.67 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Pseudomonas%20phage%20phi6%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Norovirus Hu/1968/US</b> (11 PDB entries): <br><br />
***[[4xbb]] <div class="pdb-prints 4xbb"></div><br />
***Title: 1.85A resolution structure of Norovirus 3CL protease complex with a covalently bound dipeptidyl inhibitor diethyl [(1R,2S)-2-[(N-{[(3-chlorobenzyl)oxy]carbonyl}-3-cyclohexyl-L-alanyl)amino]-1-hydroxy-3-(2-oxo-2H-pyrrol-3-yl)propyl]phosphonate<br />
***1.85 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Norovirus%20Hu/1968/US%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human rhinovirus A16</b> (10 PDB entries): <br><br />
***[[1qjy]] <div class="pdb-prints 1qjy"></div><br />
***Title: HUMAN RHINOVIRUS 16 COAT PROTEIN IN COMPLEX WITH ANTIVIRAL COMPOUND VP65099<br />
***2.8 A resolution<br />
***Other macromolecules also in this entry: Capsid protein VP3, Capsid protein VP4, Capsid protein VP2, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20rhinovirus%20A16%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human rhinovirus A2</b> (9 PDB entries): <br><br />
***[[1a3r]] <div class="pdb-prints 1a3r"></div><br />
***Title: FAB FRAGMENT (ANTIBODY 8F5) COMPLEXED WITH PEPTIDE FROM HUMAN RHINOVIRUS (SEROTYPE 2) VIRAL CAPSID PROTEIN VP2 (RESIDUES 156-170)<br />
***2.1 A resolution<br />
***Other macromolecules also in this entry: Igh protein, ENSMUSG00000076577 protein.<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20rhinovirus%20A2%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Hepatitis C virus subtype 1a</b> (7 PDB entries): <br><br />
***[[3hkw]] <div class="pdb-prints 3hkw"></div><br />
***Title: HCV NS5B genotype 1a in complex with 1,5 benzodiazepine inhibitor 6<br />
***1.55 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hepatitis%20C%20virus%20subtype%201a%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Human rhinovirus sp.</b> (6 PDB entries): <br><br />
***[[1aym]] <div class="pdb-prints 1aym"></div><br />
***Title: HUMAN RHINOVIRUS 16 COAT PROTEIN AT HIGH RESOLUTION<br />
***2.15 A resolution<br />
***Other macromolecules also in this entry: Capsid protein VP3, Capsid protein VP4, Capsid protein VP1, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Human%20rhinovirus%20sp.%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>BACTERIOPHAGE PHI-6</b> (5 PDB entries): <br><br />
***[[1uvj]] <div class="pdb-prints 1uvj"></div><br />
***Title: THE STRUCTURAL BASIS FOR RNA SPECIFICITY AND CA2 INHIBITION OF AN RNA-DEPENDENT RNA POLYMERASE PHI6P2 WITH 7NT RNA<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: 5'-R(*UP*UP*CP*CP)-3', .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22BACTERIOPHAGE%20PHI-6%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Crimean-Congo hemorrhagic fever virus strain IbAr10200</b> (4 PDB entries): <br><br />
***[[3phx]] <div class="pdb-prints 3phx"></div><br />
***Title: OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with ISG15<br />
***1.6 A resolution<br />
***Other macromolecules also in this entry: Ubiquitin-like protein ISG15, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Crimean-Congo%20hemorrhagic%20fever%20virus%20strain%20IbAr10200%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Transmissible gastroenteritis virus</b> (3 PDB entries): <br><br />
***[[1lvo]] <div class="pdb-prints 1lvo"></div><br />
***Title: Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain<br />
***1.96 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Transmissible%20gastroenteritis%20virus%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Hepatitis C virus isolate HC-J8</b> (2 PDB entries): <br><br />
***[[3gsz]] <div class="pdb-prints 3gsz"></div><br />
***Title: Structure of the genotype 2B HCV polymerase<br />
***1.9 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hepatitis%20C%20virus%20isolate%20HC-J8%22&all_molecule_names:%22RNA-directed%20RNA%20polymerase%22&!chimera:y Search for other PDB entries]<br />
**<b>Hepatitis B virus</b> (1 PDB entries): <br><br />
***[[4tn2]] <div class="pdb-prints 4tn2"></div><br />
***Title: NS5b in complex with lactam-thiophene carboxylic acids<br />
***2.7 A resolution<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=DNA_polymerase_beta&diff=2487304
DNA polymerase beta
2015-09-15T20:13:38Z
<p>PDBe: New page: <StructureSection load='2fmp' size='340' side='right' caption='The best structure for DNA polymerase beta shown: 2fmp' scene=''> Best example is PDB entry 2fmp and is shown in the view...</p>
<hr />
<div><StructureSection load='2fmp' size='340' side='right' caption='The best structure for DNA polymerase beta shown: 2fmp' scene=''><br />
Best example is PDB entry [[2fmp]] and is shown in the viewer.<br><br />
Molecule DNA polymerase beta, also known as and DNA polymerase beta.<br />
== Function ==<br />
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.Data source: Uniprot [http://www.uniprot.org/uniprot/P06746 P06746]<br><br />
==Catalytic Activity ==<br />
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).Data source: Uniprot [http://www.uniprot.org/uniprot/P06746 P06746]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
DNA repair<br><br />
DNA biosynthetic process<br><br />
immunoglobulin heavy chain V-D-J recombination<br><br />
response to gamma radiation<br><br />
DNA replication<br><br />
homeostasis of number of cells<br><br />
spleen development<br><br />
neuron apoptotic process<br><br />
base-excision repair, gap-filling<br><br />
base-excision repair<br><br />
lymph node development<br><br />
salivary gland morphogenesis<br><br />
response to ethanol<br><br />
aging<br><br />
response to hyperoxia<br><br />
somatic diversification of immunoglobulins<br><br />
cellular response to DNA damage stimulus<br><br />
inflammatory response<br><br />
apoptotic process<br><br />
somatic hypermutation of immunoglobulin genes<br><br />
pyrimidine dimer repair<br><br />
intrinsic apoptotic signaling pathway in response to DNA damage<br><br />
DNA-dependent DNA replication<br><br />
nucleotide-excision repair, DNA gap filling<br><br />
== In structures ==<br />
DNA polymerase beta is found in 264 PDB entries<br><br />
*<b>Eukaryota</b> (264 PDB entries): <br><br />
**<b>Homo sapiens</b> (230 PDB entries): <br><br />
***[[2fmp]] <div class="pdb-prints 2fmp"></div><br />
***Title: DNA Polymerase beta with a terminated gapped DNA substrate and ddCTP with sodium in the catalytic site<br />
***1.65 A resolution<br />
***Other macromolecules also in this entry: 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', 5'-D(P*GP*TP*CP*GP*G)-3', 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'.<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22DNA%20polymerase%20beta%22&!chimera:y Search for other PDB entries]<br />
**<b>Rattus norvegicus</b> (31 PDB entries): <br><br />
***[[3lqc]] <div class="pdb-prints 3lqc"></div><br />
***Title: X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain<br />
***2.349 A resolution<br />
***Other macromolecules also in this entry: DNA repair protein XRCC1..<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Rattus%20norvegicus%22&all_molecule_names:%22DNA%20polymerase%20beta%22&!chimera:y Search for other PDB entries]<br />
**<b>Leishmania infantum</b> (3 PDB entries): <br><br />
***[[4p4m]] <div class="pdb-prints 4p4m"></div><br />
***Title: Crystal structure of Leishmania infantum polymerase beta: Ternary P/T complex<br />
***1.9185 A resolution<br />
***Other macromolecules also in this entry: DNA (5'-D(*CP*AP*GP*TP*A)-3'), DNA (5'-D(P*AP*TP*AP*CP*TP*G)-3').<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Leishmania%20infantum%22&all_molecule_names:%22DNA%20polymerase%20beta%22&!chimera:y Search for other PDB entries]<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Beta-secretase_1&diff=2487302
Beta-secretase 1
2015-09-15T20:02:46Z
<p>PDBe: New page: <StructureSection load='4ivt' size='340' side='right' caption='The best structure for Beta-secretase 1 shown: 4ivt' scene=''> Best example is PDB entry 4ivt and is shown in the viewer....</p>
<hr />
<div><StructureSection load='4ivt' size='340' side='right' caption='The best structure for Beta-secretase 1 shown: 4ivt' scene=''><br />
Best example is PDB entry [[4ivt]] and is shown in the viewer.<br><br />
Molecule Beta-secretase 1, also known as Beta-site amyloid precursor protein cleaving enzyme 1, Membrane-associated aspartic protease 2, Aspartyl protease 2, Asp 2, ASP2, Memapsin-2, Beta-secretase 1 and Beta-site APP cleaving enzyme 1.<br />
== Function ==<br />
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
==Catalytic Activity ==<br />
Broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-|-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer amyloid precursor protein.Data source: Uniprot [http://www.uniprot.org/uniprot/P56817 P56817]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
== In structures ==<br />
Beta-secretase 1 is found in 326 PDB entries<br><br />
*<b>Eukaryota</b> (323 PDB entries): <br><br />
**<b>Homo sapiens</b> (324 PDB entries): <br><br />
***[[4ivt]] <div class="pdb-prints 4ivt"></div><br />
***Title: Crystal structure of BACE1 with its inhibitor<br />
***1.6 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Beta-secretase%201%22&!chimera:y Search for other PDB entries]<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Thrombin_light_chain&diff=2487301
Thrombin light chain
2015-09-15T19:59:15Z
<p>PDBe: New page: <StructureSection load='3vxe' size='340' side='right' caption='The best structure for Thrombin light chain shown: 3vxe' scene=''> Best example is PDB entry 3vxe and is shown in the vie...</p>
<hr />
<div><StructureSection load='3vxe' size='340' side='right' caption='The best structure for Thrombin light chain shown: 3vxe' scene=''><br />
Best example is PDB entry [[3vxe]] and is shown in the viewer.<br><br />
Molecule Thrombin light chain, also known as Thrombin light chain, Activation peptide fragment 2, Coagulation factor II, Prothrombin, Thrombin heavy chain and Activation peptide fragment 1.<br />
== Function ==<br />
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.Data source: Uniprot [http://www.uniprot.org/uniprot/P00734 P00734]<br><br />
==Catalytic Activity ==<br />
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.Data source: Uniprot [http://www.uniprot.org/uniprot/P00734 P00734]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
blood coagulation<br><br />
cellular protein metabolic process<br><br />
hemostasis<br><br />
multicellular organismal development<br><br />
leukocyte migration<br><br />
cellular response to mechanical stimulus<br><br />
regulation of gene expression<br><br />
response to inactivity<br><br />
negative regulation of platelet activation<br><br />
cytosolic calcium ion homeostasis<br><br />
response to wounding<br><br />
positive regulation of cell proliferation<br><br />
platelet activation<br><br />
acute-phase response<br><br />
negative regulation of proteolysis<br><br />
cell surface receptor signaling pathway<br><br />
positive regulation of release of sequestered calcium ion into cytosol<br><br />
negative regulation of astrocyte differentiation<br><br />
blood coagulation, intrinsic pathway<br><br />
regulation of cell shape<br><br />
positive regulation of protein phosphorylation<br><br />
post-translational protein modification<br><br />
positive regulation of cell growth<br><br />
positive regulation of reactive oxygen species metabolic process<br><br />
positive regulation of phosphatidylinositol 3-kinase signaling<br><br />
regulation of blood coagulation<br><br />
positive regulation of blood coagulation<br><br />
fibrinolysis<br><br />
peptidyl-glutamic acid carboxylation<br><br />
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway<br><br />
negative regulation of fibrinolysis<br><br />
positive regulation of collagen biosynthetic process<br><br />
== In structures ==<br />
Thrombin light chain is found in 397 PDB entries<br><br />
*<b>Eukaryota</b> (396 PDB entries): <br><br />
**<b>Homo sapiens</b> (361 PDB entries): <br><br />
***[[3vxe]] <div class="pdb-prints 3vxe"></div><br />
***Title: Human alpha-thrombin-Bivalirudin complex at PD5.0<br />
***1.25 A resolution<br />
***Other macromolecules also in this entry: BIVALIRUDIN, Hirudin-2, Thrombin heavy chain.<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Thrombin%20light%20chain%22&!chimera:y Search for other PDB entries]<br />
**<b>Bos taurus</b> (28 PDB entries): <br><br />
***[[2ody]] <div class="pdb-prints 2ody"></div><br />
***Title: Thrombin-bound boophilin displays a functional and accessible reactive-site loop<br />
***2.35 A resolution<br />
***Other macromolecules also in this entry: Thrombin heavy chain, Boophilin-H2, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Bos%20taurus%22&all_molecule_names:%22Thrombin%20light%20chain%22&!chimera:y Search for other PDB entries]<br />
**<b>Mus musculus</b> (7 PDB entries): <br><br />
***[[3hk3]] <div class="pdb-prints 3hk3"></div><br />
***Title: Crystal structure of murine thrombin mutant W215A/E217A (one molecule in the asymmetric unit)<br />
***1.94 A resolution<br />
***Other macromolecules also in this entry: Thrombin heavy chain..<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Mus%20musculus%22&all_molecule_names:%22Thrombin%20light%20chain%22&!chimera:y Search for other PDB entries]<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Thrombin_heavy_chain&diff=2487300
Thrombin heavy chain
2015-09-15T19:57:17Z
<p>PDBe: New page: <StructureSection load='3vxe' size='340' side='right' caption='The best structure for Thrombin heavy chain shown: 3vxe' scene=''> Best example is PDB entry 3vxe and is shown in the vie...</p>
<hr />
<div><StructureSection load='3vxe' size='340' side='right' caption='The best structure for Thrombin heavy chain shown: 3vxe' scene=''><br />
Best example is PDB entry [[3vxe]] and is shown in the viewer.<br><br />
Molecule Thrombin heavy chain, also known as Thrombin light chain, Activation peptide fragment 2, Coagulation factor II, Prothrombin, Thrombin heavy chain and Activation peptide fragment 1.<br />
== Function ==<br />
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.Data source: Uniprot [http://www.uniprot.org/uniprot/P00734 P00734]<br><br />
==Catalytic Activity ==<br />
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.Data source: Uniprot [http://www.uniprot.org/uniprot/P00734 P00734]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
blood coagulation<br><br />
cellular protein metabolic process<br><br />
hemostasis<br><br />
multicellular organismal development<br><br />
leukocyte migration<br><br />
cellular response to mechanical stimulus<br><br />
regulation of gene expression<br><br />
response to inactivity<br><br />
negative regulation of platelet activation<br><br />
cytosolic calcium ion homeostasis<br><br />
response to wounding<br><br />
positive regulation of cell proliferation<br><br />
platelet activation<br><br />
acute-phase response<br><br />
negative regulation of proteolysis<br><br />
cell surface receptor signaling pathway<br><br />
positive regulation of release of sequestered calcium ion into cytosol<br><br />
negative regulation of astrocyte differentiation<br><br />
blood coagulation, intrinsic pathway<br><br />
regulation of cell shape<br><br />
positive regulation of protein phosphorylation<br><br />
post-translational protein modification<br><br />
positive regulation of cell growth<br><br />
positive regulation of reactive oxygen species metabolic process<br><br />
positive regulation of phosphatidylinositol 3-kinase signaling<br><br />
regulation of blood coagulation<br><br />
positive regulation of blood coagulation<br><br />
fibrinolysis<br><br />
peptidyl-glutamic acid carboxylation<br><br />
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway<br><br />
negative regulation of fibrinolysis<br><br />
positive regulation of collagen biosynthetic process<br><br />
== In structures ==<br />
Thrombin heavy chain is found in 397 PDB entries<br><br />
*<b>Eukaryota</b> (397 PDB entries): <br><br />
**<b>Homo sapiens</b> (362 PDB entries): <br><br />
***[[3vxe]] <div class="pdb-prints 3vxe"></div><br />
***Title: Human alpha-thrombin-Bivalirudin complex at PD5.0<br />
***1.25 A resolution<br />
***Other macromolecules also in this entry: Thrombin light chain, BIVALIRUDIN, Hirudin-2.<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22Thrombin%20heavy%20chain%22&!chimera:y Search for other PDB entries]<br />
**<b>Bos taurus</b> (28 PDB entries): <br><br />
***[[2ody]] <div class="pdb-prints 2ody"></div><br />
***Title: Thrombin-bound boophilin displays a functional and accessible reactive-site loop<br />
***2.35 A resolution<br />
***Other macromolecules also in this entry: Thrombin light chain, Boophilin-H2, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Bos%20taurus%22&all_molecule_names:%22Thrombin%20heavy%20chain%22&!chimera:y Search for other PDB entries]<br />
**<b>Mus musculus</b> (7 PDB entries): <br><br />
***[[3hk3]] <div class="pdb-prints 3hk3"></div><br />
***Title: Crystal structure of murine thrombin mutant W215A/E217A (one molecule in the asymmetric unit)<br />
***1.94 A resolution<br />
***Other macromolecules also in this entry: Thrombin light chain..<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Mus%20musculus%22&all_molecule_names:%22Thrombin%20heavy%20chain%22&!chimera:y Search for other PDB entries]<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2487298
NADP-dependent malic enzyme
2015-09-15T19:41:35Z
<p>PDBe: </p>
<hr />
<div><StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: 3wja' scene=''><br />
Best example is PDB entry [[3wja]] and is shown in the viewer.<br><br />
Molecule NADP-dependent malic enzyme, also known as NADP-ME, NADP-dependent malic enzyme and Malic enzyme 1.<br />
==Catalytic Activity ==<br />
Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
malate metabolic process<br><br />
oxidation-reduction process<br><br />
response to carbohydrate<br><br />
response to hormone<br><br />
carbohydrate metabolic process<br><br />
protein tetramerization<br><br />
regulation of NADP metabolic process<br><br />
NADP biosynthetic process<br><br />
small molecule metabolic process<br><br />
cellular lipid metabolic process<br><br />
== In structures ==<br />
NADP-dependent malic enzyme is found in 3 PDB entries<br><br />
*<b>Eukaryota</b> (3 PDB entries): <br><br />
**<b>Homo sapiens</b> (2 PDB entries): <br><br />
***[[3wja]] <div class="pdb-prints 3wja"></div><br />
***Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form<br />
***2.548 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22NADP-dependent%20malic%20enzyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Columba livia</b> (1 PDB entries): <br><br />
***[[1gq2]] <div class="pdb-prints 1gq2"></div><br />
***Title: MALIC ENZYME FROM PIGEON LIVER<br />
***2.5 A resolution<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=Cationic_trypsin&diff=2487297
Cationic trypsin
2015-09-15T19:39:57Z
<p>PDBe: New page: <StructureSection load='2xtt' size='340' side='right' caption='The best structure for Cationic trypsin shown: 2xtt' scene=''> Best example is PDB entry 2xtt and is shown in the viewer....</p>
<hr />
<div><StructureSection load='2xtt' size='340' side='right' caption='The best structure for Cationic trypsin shown: 2xtt' scene=''><br />
Best example is PDB entry [[2xtt]] and is shown in the viewer.<br><br />
Molecule Cationic trypsin, also known as Alpha-trypsin chain 2, Alpha-trypsin chain 1, Beta-trypsin and Cationic trypsin.<br />
==Catalytic Activity ==<br />
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.Data source: Uniprot [http://www.uniprot.org/uniprot/P00760 P00760]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
proteolysis<br><br />
digestion<br><br />
== In structures ==<br />
Cationic trypsin is found in 424 PDB entries<br><br />
*<b>Eukaryota</b> (423 PDB entries): <br><br />
**<b>Bos taurus</b> (422 PDB entries): <br><br />
***[[2xtt]] <div class="pdb-prints 2xtt"></div><br />
***Title: BOVINE TRYPSIN IN COMPLEX WITH EVOLUTIONARY ENHANCED SCHISTOCERCA GREGARIA PROTEASE INHIBITOR 1 (SGPI-1-P02)<br />
***0.93 A resolution<br />
***Other macromolecules also in this entry: Protease inhibitor SGPI-1..<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Bos%20taurus%22&all_molecule_names:%22Cationic%20trypsin%22&!chimera:y Search for other PDB entries]<br />
**<b>Sus scrofa</b> (1 PDB entries): <br><br />
***[[1pph]] <div class="pdb-prints 1pph"></div><br />
***Title: GEOMETRY OF BINDING OF THE NALPHA-TOSYLATED PIPERIDIDES OF M-AMIDINO-, P-AMIDINO-AND P-GUANIDINO PHENYLALANINE TO THROMBIN AND TRYPSIN: X-RAY CRYSTAL STRUCTURES OF THEIR TRYPSIN COMPLEXES AND MODELING OF THEIR THROMBIN COMPLEXES<br />
***1.9 A resolution<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2487237
NADP-dependent malic enzyme
2015-09-12T20:45:26Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='The best structure for Lysozyme shown: 1swy' scene=''><br />
Best example is PDB entry [[1swy]] and is shown in the viewer.<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.Data source: Uniprot [http://www.uniprot.org/uniprot/P00720 P00720]<br><br />
==Catalytic Activity ==<br />
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.Data source: Uniprot [http://www.uniprot.org/uniprot/P00720 P00720]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20T4%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Streptococcus%20phage%20Cp-1%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20lambda%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20P1%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hevea%20brasiliensis%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Meretrix%20lusoria%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Bombyx%20mori%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2487236
NADP-dependent malic enzyme
2015-09-12T20:38:07Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='The best structure for Lysozyme shown: 1swy' scene=''><br />
Best example is 1swy and is shown in the viewer.<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
==Catalytic Activity ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20T4%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Streptococcus%20phage%20Cp-1%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20lambda%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20P1%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hevea%20brasiliensis%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Meretrix%20lusoria%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Bombyx%20mori%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2487235
NADP-dependent malic enzyme
2015-09-12T20:33:44Z
<p>PDBe: </p>
<hr />
<div>xml format<br />
Viruses<br />
Eukaryota<br />
Bacteria<br />
== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='The best structure for Lysozyme shown: 1swy' scene=''><br />
Best example is 1swy and is shown in the viewer.<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
==Catalytic Activity ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20T4%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Streptococcus%20phage%20Cp-1%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20lambda%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20P1%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hevea%20brasiliensis%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Meretrix%20lusoria%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Bombyx%20mori%22&all_molecule_names:%22Lysozyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
[[Category:Topic Page]][[Category:PDBe]]</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2479359
NADP-dependent malic enzyme
2015-09-11T14:55:45Z
<p>PDBe: </p>
<hr />
<div>== NADP-dependent malic enzyme ==<br />
<StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: 3wja' scene=''><br />
Best example is 3wja and is shown in the viewer.<br><br />
Molecule NADP-dependent malic enzyme, also known as NADP-ME, NADP-dependent malic enzyme and Malic enzyme 1.<br />
==Catalytic Activity ==<br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
malate metabolic process<br><br />
oxidation-reduction process<br><br />
response to carbohydrate<br><br />
response to hormone<br><br />
carbohydrate metabolic process<br><br />
protein tetramerization<br><br />
regulation of NADP metabolic process<br><br />
NADP biosynthetic process<br><br />
small molecule metabolic process<br><br />
cellular lipid metabolic process<br><br />
== In structures ==<br />
NADP-dependent malic enzyme is found in 3 PDB entries<br><br />
*<b>Eukaryota</b> (3 PDB entries): <br><br />
**<b>Homo sapiens</b> (2 PDB entries): <br><br />
***[[3wja]] <div class="pdb-prints 3wja"></div><br />
***Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form<br />
***2.548 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22NADP-dependent%20malic%20enzyme%22&!chimera:y Search for other PDB entries]<br />
**<b>Columba livia</b> (1 PDB entries): <br><br />
***[[1gq2]] <div class="pdb-prints 1gq2"></div><br />
***Title: MALIC ENZYME FROM PIGEON LIVER<br />
***2.5 A resolution</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2478922
NADP-dependent malic enzyme
2015-09-11T14:31:34Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='The best structure for Lysozyme shown: 1swy' scene=''><br />
Best example is 1swy and is shown in the viewer.<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.Data source: Uniprot [http://www.uniprot.org/uniprot/P00720 P00720]<br><br />
==Catalytic Activity ==<br />
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.Data source: Uniprot [http://www.uniprot.org/uniprot/P00720 P00720]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br />
***Title: The cryoEM structure of human gamma-Secretase complex<br />
***Experimental EM map [http://pdbe.org/emd-2974 emd-2974].<br />
***4.4 A resolution<br />
***Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .<br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Hevea%20brasiliensis%22&all_molecule_names:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Meretrix%20lusoria%22&all_molecule_names:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br />
***Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br />
***2.4 A resolution<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br />
***Title: Crystal Structure of Tapes japonica Lysozyme<br />
***1.6 A resolution<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Bombyx%20mori%22&all_molecule_names:%22Lysozyme%22 Search for other PDB entries]<br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br />
***Title: crystal structure of P22 lysozyme mutant L86M<br />
***1.04 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20P22%22&all_molecule_names:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br />
***Title: Crystal structure of truncated endolysin R21 from phage 21<br />
***1.7 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20P21%22&all_molecule_names:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20T4%22&all_molecule_names:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br />
***Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br />
***N/A A resolution<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20lambda%22&all_molecule_names:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Enterobacteria%20phage%20P1%22&all_molecule_names:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Streptococcus%20phage%20Cp-1%22&all_molecule_names:%22Lysozyme%22 Search for other PDB entries]<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2478865
NADP-dependent malic enzyme
2015-09-11T14:28:12Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='The best structure for Lysozyme shown: 1swy' scene=''><br />
Best example is 1swy and is shown in the viewer.<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.Data source: Uniprot [http://www.uniprot.org/uniprot/P00720 P00720]<br><br />
==Catalytic Activity ==<br />
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.Data source: Uniprot [http://www.uniprot.org/uniprot/P00720 P00720]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br />
***Title: The cryoEM structure of human gamma-Secretase complex<br />
***Experimental EM map [http://pdbe.org/emd-2974 emd-2974].<br />
***4.4 A resolution<br />
***Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .<br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Hevea%20brasiliensis%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Meretrix%20lusoria%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br />
***Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br />
***2.4 A resolution<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br />
***Title: Crystal Structure of Tapes japonica Lysozyme<br />
***1.6 A resolution<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Bombyx%20mori%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br />
***Title: crystal structure of P22 lysozyme mutant L86M<br />
***1.04 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20P22%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br />
***Title: Crystal structure of truncated endolysin R21 from phage 21<br />
***1.7 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20P21%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20T4%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br />
***Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br />
***N/A A resolution<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20lambda%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20P1%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Streptococcus%20phage%20Cp-1%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2478855
NADP-dependent malic enzyme
2015-09-11T14:27:40Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='The best structure for Lysozyme shown: 1swy' scene=''><br />
Best example is 1swy and is shown in the viewer.<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.Data source: Uniprot [http://www.uniprot.org/uniprot/P00720 P00720]<br><br />
==Catalytic Activity ==<br><br />
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.Data source: Uniprot [http://www.uniprot.org/uniprot/P00720 P00720]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br />
***Title: The cryoEM structure of human gamma-Secretase complex<br />
***Experimental EM map [http://pdbe.org/emd-2974 emd-2974].<br />
***4.4 A resolution<br />
***Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .<br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Hevea%20brasiliensis%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Meretrix%20lusoria%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br />
***Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br />
***2.4 A resolution<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br />
***Title: Crystal Structure of Tapes japonica Lysozyme<br />
***1.6 A resolution<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Bombyx%20mori%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br />
***Title: crystal structure of P22 lysozyme mutant L86M<br />
***1.04 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20P22%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br />
***Title: Crystal structure of truncated endolysin R21 from phage 21<br />
***1.7 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20P21%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20T4%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br />
***Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br />
***N/A A resolution<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20lambda%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20P1%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Streptococcus%20phage%20Cp-1%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2478826
NADP-dependent malic enzyme
2015-09-11T14:25:58Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='The best structure for Lysozyme shown: 1swy' scene=''><br />
Best example is 1swy and is shown in the viewer.<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.data source: Uniprot [http://www.uniprot.org/uniprot/P00720]<br><br />
==Catalytic Activity ==<br><br />
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.data source: Uniprot [http://www.uniprot.org/uniprot/P00720]<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br />
***Title: The cryoEM structure of human gamma-Secretase complex<br />
***Experimental EM map [http://pdbe.org/emd-2974 emd-2974].<br />
***4.4 A resolution<br />
***Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .<br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Hevea%20brasiliensis%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Meretrix%20lusoria%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br />
***Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br />
***2.4 A resolution<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br />
***Title: Crystal Structure of Tapes japonica Lysozyme<br />
***1.6 A resolution<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Bombyx%20mori%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br />
***Title: crystal structure of P22 lysozyme mutant L86M<br />
***1.04 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20P22%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br />
***Title: Crystal structure of truncated endolysin R21 from phage 21<br />
***1.7 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20P21%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20T4%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br />
***Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br />
***N/A A resolution<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20lambda%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Enterobacteria%20phage%20P1%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%22Streptococcus%20phage%20Cp-1%22%20AND%20molecule_name:%22Lysozyme%22 Search for other PDB entries]<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2447760
NADP-dependent malic enzyme
2015-09-10T08:41:39Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br />
***Title: The cryoEM structure of human gamma-Secretase complex<br />
***Experimental EM map [http://pdbe.org/emd-2974 emd-2974].<br />
***4.4 A resolution<br />
***Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .<br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Hevea%20brasiliensis%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Meretrix%20lusoria%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br />
***Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br />
***2.4 A resolution<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br />
***Title: Crystal Structure of Tapes japonica Lysozyme<br />
***1.6 A resolution<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Bombyx%20mori%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br />
***Title: crystal structure of P22 lysozyme mutant L86M<br />
***1.04 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P22%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br />
***Title: Crystal structure of truncated endolysin R21 from phage 21<br />
***1.7 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P21%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20T4%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br />
***Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br />
***N/A A resolution<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20lambda%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P1%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Streptococcus%20phage%20Cp-1%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2447596
NADP-dependent malic enzyme
2015-09-10T08:32:44Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
{{#tree:id=test| openlevels=0|<br />
* top<br />
** second<br />
*** third<br />
}}<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br />
***Title: The cryoEM structure of human gamma-Secretase complex<br />
***Experimental EM map [http://pdbe.org/emd-2974 emd-2974].<br />
***4.4 A resolution<br />
***Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .<br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Hevea%20brasiliensis%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Meretrix%20lusoria%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br />
***Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br />
***2.4 A resolution<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br />
***Title: Crystal Structure of Tapes japonica Lysozyme<br />
***1.6 A resolution<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Bombyx%20mori%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br />
***Title: crystal structure of P22 lysozyme mutant L86M<br />
***1.04 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P22%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br />
***Title: Crystal structure of truncated endolysin R21 from phage 21<br />
***1.7 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P21%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20T4%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br />
***Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br />
***N/A A resolution<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20lambda%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P1%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Streptococcus%20phage%20Cp-1%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2446656
NADP-dependent malic enzyme
2015-09-10T07:35:43Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br />
***Title: The cryoEM structure of human gamma-Secretase complex<br />
***Experimental EM map [http://pdbe.org/emd-2974 emd-2974].<br />
***4.4 A resolution<br />
***Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .<br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Hevea%20brasiliensis%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Meretrix%20lusoria%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br />
***Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br />
***2.4 A resolution<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br />
***Title: Crystal Structure of Tapes japonica Lysozyme<br />
***1.6 A resolution<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Bombyx%20mori%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br />
***Title: crystal structure of P22 lysozyme mutant L86M<br />
***1.04 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P22%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br />
***Title: Crystal structure of truncated endolysin R21 from phage 21<br />
***1.7 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P21%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20T4%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br />
***Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br />
***N/A A resolution<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20lambda%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P1%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Streptococcus%20phage%20Cp-1%34%20AND%20molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435990
NADP-dependent malic enzyme
2015-09-09T20:47:23Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br />
***Title: The cryoEM structure of human gamma-Secretase complex<br />
***Experimental EM map [http://pdbe.org/emd-2974 emd-2974].<br />
***4.4 A resolution<br />
***Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .<br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Hevea%20brasiliensis%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Meretrix%20lusoria%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br />
***Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br />
***2.4 A resolution<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br />
***Title: Crystal Structure of Tapes japonica Lysozyme<br />
***1.6 A resolution<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Bombyx%20mori%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br />
***Title: crystal structure of P22 lysozyme mutant L86M<br />
***1.04 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P22%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br />
***Title: Crystal structure of truncated endolysin R21 from phage 21<br />
***1.7 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P21%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20T4%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br />
***Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br />
***N/A A resolution<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20lambda%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P1%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Streptococcus%20phage%20Cp-1%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435955
NADP-dependent malic enzyme
2015-09-09T20:45:18Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br />
***Title: The cryoEM structure of human gamma-Secretase complex<br />
***Experimental EM map [http://pdbe.org/emd-2974 emd-2974].<br />
***4.4 A resolution<br />
***Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .<br />
<br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Hevea%20brasiliensis%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Meretrix%20lusoria%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br />
***Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br />
***2.4 A resolution<br />
<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br />
***Title: Crystal Structure of Tapes japonica Lysozyme<br />
***1.6 A resolution<br />
<br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
<br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Bombyx%20mori%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br />
***Title: crystal structure of P22 lysozyme mutant L86M<br />
***1.04 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P22%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br />
***Title: Crystal structure of truncated endolysin R21 from phage 21<br />
***1.7 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P21%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20T4%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br />
***Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br />
***N/A A resolution<br />
<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20lambda%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P1%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Streptococcus%20phage%20Cp-1%34&molecule_name:%34Lysozyme%34 Search for other PDB entries]<br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
<br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435905
NADP-dependent malic enzyme
2015-09-09T20:41:28Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<b>Eukaryota</b> (16 PDB entries): <br><br />
**<b>Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br />
***Title: The cryoEM structure of human gamma-Secretase complex<br />
***Experimental EM map [http://pdbe.org/emd-2974 emd-2974].<br />
***4.4 A resolution<br />
***Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .<br />
<br/><br />
**<b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br />
***Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br />
***1.92 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Hevea%20brasiliensis%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
**<b>Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br />
***Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br />
***1.24 A resolution<br />
***Other macromolecules also in this entry: Putative exported protein, .<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Meretrix%20lusoria%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
**<b>Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br />
***Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br />
***2.4 A resolution<br />
<br />
<br/><br />
**<b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br />
***Title: Crystal Structure of Tapes japonica Lysozyme<br />
***1.6 A resolution<br />
<br />
<br/><br />
**<b>Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br />
***Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br />
***1.9 A resolution<br />
***Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.<br />
<br/><br />
**<b>Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br />
***Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br />
***2.5 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Bombyx%20mori%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
*<b>Viruses</b> (578 PDB entries): <br><br />
**<b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br />
***Title: crystal structure of P22 lysozyme mutant L86M<br />
***1.04 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P22%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
**<b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br />
***Title: Crystal structure of truncated endolysin R21 from phage 21<br />
***1.7 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P21%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
**<b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br />
***Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br />
***1.06 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20T4%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
**<b>Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br />
***Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br />
***N/A A resolution<br />
<br />
<br/><br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br />
***Title: Lysozyme from bacteriophage lambda<br />
***2.3 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20lambda%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br />
***Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br />
***1.666 A resolution<br />
<br />
<br/><br />
**<b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br />
***Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br />
***1.07 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P1%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br />
***Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br />
***1.69 A resolution<br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Streptococcus%20phage%20Cp-1%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
*<b>Bacteria</b> (1 PDB entries): <br><br />
**<b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
<br/><br />
**<b>Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br />
***Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br />
***2.56 A resolution<br />
***Other macromolecules also in this entry: Transcription factor ETV6, .<br />
<br/></div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435858
NADP-dependent malic enzyme
2015-09-09T20:38:12Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
*<br><b>Eukaryota</b> (16 PDB entries): <br><br />
**<br><b>Homo sapiens</b> (1 PDB entries): <br><br />
[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br/><br />
**<br><b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Hevea%20brasiliensis%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
**<br><b>Meretrix lusoria</b> (3 PDB entries): <br><br />
<br />
<br><b>Eukaryota</b> (16 PDB entries): <br><br><b>Homo sapiens</b> (1 PDB entries): <br><br />
[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br/><br />
<br><b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Hevea%20brasiliensis%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Meretrix lusoria</b> (3 PDB entries): <br><br />
[[4pj2]] <div class="pdb-prints 4pj2"></div><br><br>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br> <br />
1.24 A resolution <br><br />
Other macromolecules also in this entry: Putative exported protein, . <br><br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Meretrix%20lusoria%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Antheraea mylitta</b> (1 PDB entries): <br><br />
[[1iiz]] <div class="pdb-prints 1iiz"></div><br><br>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br> <br />
2.4 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
[[2dqa]] <div class="pdb-prints 2dqa"></div><br><br>Title: Crystal Structure of Tapes japonica Lysozyme<br> <br />
1.6 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Mus musculus</b> (1 PDB entries): <br><br />
[[1iak]] <div class="pdb-prints 1iak"></div><br><br>Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br> <br />
1.9 A resolution <br><br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br><br><br />
<br/><br />
<br><b>Bombyx mori</b> (2 PDB entries): <br><br />
[[1gd6]] <div class="pdb-prints 1gd6"></div><br><br>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br> <br />
2.5 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Bombyx%20mori%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Viruses</b> (578 PDB entries): <br><br><b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
[[2anv]] <div class="pdb-prints 2anv"></div><br><br>Title: crystal structure of P22 lysozyme mutant L86M<br> <br />
1.04 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P22%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
[[3hdf]] <div class="pdb-prints 3hdf"></div><br><br>Title: Crystal structure of truncated endolysin R21 from phage 21<br> <br />
1.7 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P21%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
[[1swy]] <div class="pdb-prints 1swy"></div><br><br>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br> <br />
1.06 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20T4%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Escherichia phage T5</b> (1 PDB entries): <br><br />
[[2mxz]] <div class="pdb-prints 2mxz"></div><br><br>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br> <br />
N/A A resolution <br><br />
<br><br />
<br/><br />
<br><b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
[[1am7]] <div class="pdb-prints 1am7"></div><br><br>Title: Lysozyme from bacteriophage lambda<br> <br />
2.3 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20lambda%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
[[4cvd]] <div class="pdb-prints 4cvd"></div><br><br>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br> <br />
1.666 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
[[1xju]] <div class="pdb-prints 1xju"></div><br><br>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br> <br />
1.07 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P1%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
[[2j8g]] <div class="pdb-prints 2j8g"></div><br><br>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br> <br />
1.69 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Streptococcus%20phage%20Cp-1%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Bacteria</b> (1 PDB entries): <br><br><b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/><br />
<br><b>Escherichia coli</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/></div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435792
NADP-dependent malic enzyme
2015-09-09T20:32:42Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
<br><b>Eukaryota</b> (16 PDB entries): <br><br><b>Homo sapiens</b> (1 PDB entries): <br><br />
[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br/><br />
<br><b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Hevea%20brasiliensis%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Meretrix lusoria</b> (3 PDB entries): <br><br />
[[4pj2]] <div class="pdb-prints 4pj2"></div><br><br>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br> <br />
1.24 A resolution <br><br />
Other macromolecules also in this entry: Putative exported protein, . <br><br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Meretrix%20lusoria%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Antheraea mylitta</b> (1 PDB entries): <br><br />
[[1iiz]] <div class="pdb-prints 1iiz"></div><br><br>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br> <br />
2.4 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
[[2dqa]] <div class="pdb-prints 2dqa"></div><br><br>Title: Crystal Structure of Tapes japonica Lysozyme<br> <br />
1.6 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Mus musculus</b> (1 PDB entries): <br><br />
[[1iak]] <div class="pdb-prints 1iak"></div><br><br>Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br> <br />
1.9 A resolution <br><br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br><br><br />
<br/><br />
<br><b>Bombyx mori</b> (2 PDB entries): <br><br />
[[1gd6]] <div class="pdb-prints 1gd6"></div><br><br>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br> <br />
2.5 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Bombyx%20mori%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Viruses</b> (578 PDB entries): <br><br><b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
[[2anv]] <div class="pdb-prints 2anv"></div><br><br>Title: crystal structure of P22 lysozyme mutant L86M<br> <br />
1.04 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P22%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
[[3hdf]] <div class="pdb-prints 3hdf"></div><br><br>Title: Crystal structure of truncated endolysin R21 from phage 21<br> <br />
1.7 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P21%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
[[1swy]] <div class="pdb-prints 1swy"></div><br><br>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br> <br />
1.06 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20T4%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Escherichia phage T5</b> (1 PDB entries): <br><br />
[[2mxz]] <div class="pdb-prints 2mxz"></div><br><br>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br> <br />
N/A A resolution <br><br />
<br><br />
<br/><br />
<br><b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
[[1am7]] <div class="pdb-prints 1am7"></div><br><br>Title: Lysozyme from bacteriophage lambda<br> <br />
2.3 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20lambda%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
[[4cvd]] <div class="pdb-prints 4cvd"></div><br><br>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br> <br />
1.666 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
[[1xju]] <div class="pdb-prints 1xju"></div><br><br>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br> <br />
1.07 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Enterobacteria%20phage%20P1%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
[[2j8g]] <div class="pdb-prints 2j8g"></div><br><br>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br> <br />
1.69 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:%34Streptococcus%20phage%20Cp-1%34&molecule_name:%34Lysozyme%34 Search for other PDB entries] <br/><br />
<br><b>Bacteria</b> (1 PDB entries): <br><br><b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/><br />
<br><b>Escherichia coli</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/></div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435681
NADP-dependent malic enzyme
2015-09-09T20:15:42Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
<br><b>Eukaryota</b> (16 PDB entries): <br><br><b>Homo sapiens</b> (1 PDB entries): <br><br />
[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br/><br />
<br><b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Hevea brasiliensis"&molecule_name:"Lysozyme"| Search for other PDB entries] <br/><br />
<br><b>Meretrix lusoria</b> (3 PDB entries): <br><br />
[[4pj2]] <div class="pdb-prints 4pj2"></div><br><br>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br> <br />
1.24 A resolution <br><br />
Other macromolecules also in this entry: Putative exported protein, . <br><br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Antheraea mylitta</b> (1 PDB entries): <br><br />
[[1iiz]] <div class="pdb-prints 1iiz"></div><br><br>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br> <br />
2.4 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
[[2dqa]] <div class="pdb-prints 2dqa"></div><br><br>Title: Crystal Structure of Tapes japonica Lysozyme<br> <br />
1.6 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Mus musculus</b> (1 PDB entries): <br><br />
[[1iak]] <div class="pdb-prints 1iak"></div><br><br>Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br> <br />
1.9 A resolution <br><br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br><br><br />
<br/><br />
<br><b>Bombyx mori</b> (2 PDB entries): <br><br />
[[1gd6]] <div class="pdb-prints 1gd6"></div><br><br>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br> <br />
2.5 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Viruses</b> (578 PDB entries): <br><br><b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
[[2anv]] <div class="pdb-prints 2anv"></div><br><br>Title: crystal structure of P22 lysozyme mutant L86M<br> <br />
1.04 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
[[3hdf]] <div class="pdb-prints 3hdf"></div><br><br>Title: Crystal structure of truncated endolysin R21 from phage 21<br> <br />
1.7 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
[[1swy]] <div class="pdb-prints 1swy"></div><br><br>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br> <br />
1.06 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Escherichia phage T5</b> (1 PDB entries): <br><br />
[[2mxz]] <div class="pdb-prints 2mxz"></div><br><br>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br> <br />
N/A A resolution <br><br />
<br><br />
<br/><br />
<br><b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
[[1am7]] <div class="pdb-prints 1am7"></div><br><br>Title: Lysozyme from bacteriophage lambda<br> <br />
2.3 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
[[4cvd]] <div class="pdb-prints 4cvd"></div><br><br>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br> <br />
1.666 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
[[1xju]] <div class="pdb-prints 1xju"></div><br><br>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br> <br />
1.07 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
[[2j8g]] <div class="pdb-prints 2j8g"></div><br><br>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br> <br />
1.69 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Bacteria</b> (1 PDB entries): <br><br><b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/><br />
<br><b>Escherichia coli</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/></div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435680
NADP-dependent malic enzyme
2015-09-09T20:12:27Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
{{#tree: id=OrganizedByTopic|openlevels=0|<br />
*Item<br />
**sub item<br />
**Another sub-item<br />
}}<br />
<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
{{#tree:<br />
*<b>Eukaryota<b> 16 PDB entries<br />
**<b>Homo sapiens</b> 1 PDB entries<br />
***[[4uis]]Title: The cryoEM structure of human gamma-Secretase complex <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br />
**<b>Hevea brasiliensis</b> 7 PDB entries<br />
***[[1kqy]]Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG <br />
1.92 A resolution <br />
<br />
**<b>Meretrix lusoria</b> 3 PDB entries<br />
***[[4pj2]]Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme <br />
1.24 A resolution <br />
Other macromolecules also in this entry: Putative exported protein, . <br />
**<b>Antheraea mylitta</b> 1 PDB entries<br />
***[[1iiz]]Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta <br />
2.4 A resolution <br />
<br />
**<b>Ruditapes philippinarum</b> 1 PDB entries<br />
***[[2dqa]]Title: Crystal Structure of Tapes japonica Lysozyme <br />
1.6 A resolution <br />
<br />
**<b>Mus musculus</b> 1 PDB entries<br />
***[[1iak]]Title: HISTOCOMPATIBILITY ANTIGEN I-AK <br />
1.9 A resolution <br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br />
**<b>Bombyx mori</b> 2 PDB entries<br />
***[[1gd6]]Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME <br />
2.5 A resolution <br />
<br />
*<b>Viruses<b> 578 PDB entries<br />
**<b>Enterobacteria phage P22</b> 2 PDB entries<br />
***[[2anv]]Title: crystal structure of P22 lysozyme mutant L86M <br />
1.04 A resolution <br />
<br />
**<b>Enterobacteria phage P21</b> 2 PDB entries<br />
***[[3hdf]]Title: Crystal structure of truncated endolysin R21 from phage 21 <br />
1.7 A resolution <br />
<br />
**<b>Enterobacteria phage T4</b> 561 PDB entries<br />
***[[1swy]]Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination <br />
1.06 A resolution <br />
<br />
**<b>Escherichia phage T5</b> 1 PDB entries<br />
***[[2mxz]]Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+) <br />
N/A A resolution <br />
<br />
**<b>Enterobacteria phage lambda</b> 3 PDB entries<br />
***[[1am7]]Title: Lysozyme from bacteriophage lambda <br />
2.3 A resolution <br />
<br />
**<b>Streptococcus phage CP-7</b> 1 PDB entries<br />
***[[4cvd]]Title: Crystal structure of the central repeat of cell wall binding module of Cpl7 <br />
1.666 A resolution <br />
<br />
**<b>Enterobacteria phage P1</b> 2 PDB entries<br />
***[[1xju]]Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz <br />
1.07 A resolution <br />
<br />
**<b>Streptococcus phage Cp-1</b> 6 PDB entries<br />
***[[2j8g]]Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide) <br />
1.69 A resolution <br />
<br />
*<b>Bacteria<b> 1 PDB entries<br />
**<b>Enterobacteria phage T4</b> 1 PDB entries<br />
***[[2qb0]]Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
**<b>Escherichia coli</b> 1 PDB entries<br />
***[[2qb0]]Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
}}</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435679
NADP-dependent malic enzyme
2015-09-09T20:11:43Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
{{#tree: id=OrganizedByTopic|openlevels=0|<br />
*Item<br />
**[[Sub-item link]]<br />
**Another sub-item<br />
}}<br />
<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
{{#tree:<br />
*<b>Eukaryota<b> 16 PDB entries<br />
**<b>Homo sapiens</b> 1 PDB entries<br />
***[[4uis]]Title: The cryoEM structure of human gamma-Secretase complex <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br />
**<b>Hevea brasiliensis</b> 7 PDB entries<br />
***[[1kqy]]Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG <br />
1.92 A resolution <br />
<br />
**<b>Meretrix lusoria</b> 3 PDB entries<br />
***[[4pj2]]Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme <br />
1.24 A resolution <br />
Other macromolecules also in this entry: Putative exported protein, . <br />
**<b>Antheraea mylitta</b> 1 PDB entries<br />
***[[1iiz]]Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta <br />
2.4 A resolution <br />
<br />
**<b>Ruditapes philippinarum</b> 1 PDB entries<br />
***[[2dqa]]Title: Crystal Structure of Tapes japonica Lysozyme <br />
1.6 A resolution <br />
<br />
**<b>Mus musculus</b> 1 PDB entries<br />
***[[1iak]]Title: HISTOCOMPATIBILITY ANTIGEN I-AK <br />
1.9 A resolution <br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br />
**<b>Bombyx mori</b> 2 PDB entries<br />
***[[1gd6]]Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME <br />
2.5 A resolution <br />
<br />
*<b>Viruses<b> 578 PDB entries<br />
**<b>Enterobacteria phage P22</b> 2 PDB entries<br />
***[[2anv]]Title: crystal structure of P22 lysozyme mutant L86M <br />
1.04 A resolution <br />
<br />
**<b>Enterobacteria phage P21</b> 2 PDB entries<br />
***[[3hdf]]Title: Crystal structure of truncated endolysin R21 from phage 21 <br />
1.7 A resolution <br />
<br />
**<b>Enterobacteria phage T4</b> 561 PDB entries<br />
***[[1swy]]Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination <br />
1.06 A resolution <br />
<br />
**<b>Escherichia phage T5</b> 1 PDB entries<br />
***[[2mxz]]Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+) <br />
N/A A resolution <br />
<br />
**<b>Enterobacteria phage lambda</b> 3 PDB entries<br />
***[[1am7]]Title: Lysozyme from bacteriophage lambda <br />
2.3 A resolution <br />
<br />
**<b>Streptococcus phage CP-7</b> 1 PDB entries<br />
***[[4cvd]]Title: Crystal structure of the central repeat of cell wall binding module of Cpl7 <br />
1.666 A resolution <br />
<br />
**<b>Enterobacteria phage P1</b> 2 PDB entries<br />
***[[1xju]]Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz <br />
1.07 A resolution <br />
<br />
**<b>Streptococcus phage Cp-1</b> 6 PDB entries<br />
***[[2j8g]]Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide) <br />
1.69 A resolution <br />
<br />
*<b>Bacteria<b> 1 PDB entries<br />
**<b>Enterobacteria phage T4</b> 1 PDB entries<br />
***[[2qb0]]Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
**<b>Escherichia coli</b> 1 PDB entries<br />
***[[2qb0]]Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
}}</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435678
NADP-dependent malic enzyme
2015-09-09T20:10:44Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
{{#tree: minExpandLevel=2 |<br />
*Item<br />
**[[Sub-item link]]<br />
**Another sub-item<br />
}}<br />
<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
{{#tree:<br />
*<b>Eukaryota<b> 16 PDB entries<br />
**<b>Homo sapiens</b> 1 PDB entries<br />
***[[4uis]]Title: The cryoEM structure of human gamma-Secretase complex <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br />
**<b>Hevea brasiliensis</b> 7 PDB entries<br />
***[[1kqy]]Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG <br />
1.92 A resolution <br />
<br />
**<b>Meretrix lusoria</b> 3 PDB entries<br />
***[[4pj2]]Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme <br />
1.24 A resolution <br />
Other macromolecules also in this entry: Putative exported protein, . <br />
**<b>Antheraea mylitta</b> 1 PDB entries<br />
***[[1iiz]]Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta <br />
2.4 A resolution <br />
<br />
**<b>Ruditapes philippinarum</b> 1 PDB entries<br />
***[[2dqa]]Title: Crystal Structure of Tapes japonica Lysozyme <br />
1.6 A resolution <br />
<br />
**<b>Mus musculus</b> 1 PDB entries<br />
***[[1iak]]Title: HISTOCOMPATIBILITY ANTIGEN I-AK <br />
1.9 A resolution <br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br />
**<b>Bombyx mori</b> 2 PDB entries<br />
***[[1gd6]]Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME <br />
2.5 A resolution <br />
<br />
*<b>Viruses<b> 578 PDB entries<br />
**<b>Enterobacteria phage P22</b> 2 PDB entries<br />
***[[2anv]]Title: crystal structure of P22 lysozyme mutant L86M <br />
1.04 A resolution <br />
<br />
**<b>Enterobacteria phage P21</b> 2 PDB entries<br />
***[[3hdf]]Title: Crystal structure of truncated endolysin R21 from phage 21 <br />
1.7 A resolution <br />
<br />
**<b>Enterobacteria phage T4</b> 561 PDB entries<br />
***[[1swy]]Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination <br />
1.06 A resolution <br />
<br />
**<b>Escherichia phage T5</b> 1 PDB entries<br />
***[[2mxz]]Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+) <br />
N/A A resolution <br />
<br />
**<b>Enterobacteria phage lambda</b> 3 PDB entries<br />
***[[1am7]]Title: Lysozyme from bacteriophage lambda <br />
2.3 A resolution <br />
<br />
**<b>Streptococcus phage CP-7</b> 1 PDB entries<br />
***[[4cvd]]Title: Crystal structure of the central repeat of cell wall binding module of Cpl7 <br />
1.666 A resolution <br />
<br />
**<b>Enterobacteria phage P1</b> 2 PDB entries<br />
***[[1xju]]Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz <br />
1.07 A resolution <br />
<br />
**<b>Streptococcus phage Cp-1</b> 6 PDB entries<br />
***[[2j8g]]Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide) <br />
1.69 A resolution <br />
<br />
*<b>Bacteria<b> 1 PDB entries<br />
**<b>Enterobacteria phage T4</b> 1 PDB entries<br />
***[[2qb0]]Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
**<b>Escherichia coli</b> 1 PDB entries<br />
***[[2qb0]]Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
}}</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435677
NADP-dependent malic enzyme
2015-09-09T20:09:41Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
{{#tree:<br />
*<b>Eukaryota<b> 16 PDB entries<br />
**<b>Homo sapiens</b> 1 PDB entries<br />
***[[4uis]]Title: The cryoEM structure of human gamma-Secretase complex <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br />
**<b>Hevea brasiliensis</b> 7 PDB entries<br />
***[[1kqy]]Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG <br />
1.92 A resolution <br />
<br />
**<b>Meretrix lusoria</b> 3 PDB entries<br />
***[[4pj2]]Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme <br />
1.24 A resolution <br />
Other macromolecules also in this entry: Putative exported protein, . <br />
**<b>Antheraea mylitta</b> 1 PDB entries<br />
***[[1iiz]]Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta <br />
2.4 A resolution <br />
<br />
**<b>Ruditapes philippinarum</b> 1 PDB entries<br />
***[[2dqa]]Title: Crystal Structure of Tapes japonica Lysozyme <br />
1.6 A resolution <br />
<br />
**<b>Mus musculus</b> 1 PDB entries<br />
***[[1iak]]Title: HISTOCOMPATIBILITY ANTIGEN I-AK <br />
1.9 A resolution <br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br />
**<b>Bombyx mori</b> 2 PDB entries<br />
***[[1gd6]]Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME <br />
2.5 A resolution <br />
<br />
*<b>Viruses<b> 578 PDB entries<br />
**<b>Enterobacteria phage P22</b> 2 PDB entries<br />
***[[2anv]]Title: crystal structure of P22 lysozyme mutant L86M <br />
1.04 A resolution <br />
<br />
**<b>Enterobacteria phage P21</b> 2 PDB entries<br />
***[[3hdf]]Title: Crystal structure of truncated endolysin R21 from phage 21 <br />
1.7 A resolution <br />
<br />
**<b>Enterobacteria phage T4</b> 561 PDB entries<br />
***[[1swy]]Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination <br />
1.06 A resolution <br />
<br />
**<b>Escherichia phage T5</b> 1 PDB entries<br />
***[[2mxz]]Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+) <br />
N/A A resolution <br />
<br />
**<b>Enterobacteria phage lambda</b> 3 PDB entries<br />
***[[1am7]]Title: Lysozyme from bacteriophage lambda <br />
2.3 A resolution <br />
<br />
**<b>Streptococcus phage CP-7</b> 1 PDB entries<br />
***[[4cvd]]Title: Crystal structure of the central repeat of cell wall binding module of Cpl7 <br />
1.666 A resolution <br />
<br />
**<b>Enterobacteria phage P1</b> 2 PDB entries<br />
***[[1xju]]Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz <br />
1.07 A resolution <br />
<br />
**<b>Streptococcus phage Cp-1</b> 6 PDB entries<br />
***[[2j8g]]Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide) <br />
1.69 A resolution <br />
<br />
*<b>Bacteria<b> 1 PDB entries<br />
**<b>Enterobacteria phage T4</b> 1 PDB entries<br />
***[[2qb0]]Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
**<b>Escherichia coli</b> 1 PDB entries<br />
***[[2qb0]]Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
}}</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435676
NADP-dependent malic enzyme
2015-09-09T20:07:13Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
{{#tree:*<b>Eukaryota<b> 16 PDB entries**<b>Homo sapiens</b> 1 PDB entries<br />
***[[4uis]]Title: The cryoEM structure of human gamma-Secretase complex <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br />
**<b>Hevea brasiliensis</b> 7 PDB entries<br />
***[[1kqy]]Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG <br />
1.92 A resolution <br />
<br />
**<b>Meretrix lusoria</b> 3 PDB entries<br />
***[[4pj2]]Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme <br />
1.24 A resolution <br />
Other macromolecules also in this entry: Putative exported protein, . <br />
**<b>Antheraea mylitta</b> 1 PDB entries<br />
***[[1iiz]]Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta <br />
2.4 A resolution <br />
<br />
**<b>Ruditapes philippinarum</b> 1 PDB entries<br />
***[[2dqa]]Title: Crystal Structure of Tapes japonica Lysozyme <br />
1.6 A resolution <br />
<br />
**<b>Mus musculus</b> 1 PDB entries<br />
***[[1iak]]Title: HISTOCOMPATIBILITY ANTIGEN I-AK <br />
1.9 A resolution <br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br />
**<b>Bombyx mori</b> 2 PDB entries<br />
***[[1gd6]]Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME <br />
2.5 A resolution <br />
<br />
*<b>Viruses<b> 578 PDB entries**<b>Enterobacteria phage P22</b> 2 PDB entries<br />
***[[2anv]]Title: crystal structure of P22 lysozyme mutant L86M <br />
1.04 A resolution <br />
<br />
**<b>Enterobacteria phage P21</b> 2 PDB entries<br />
***[[3hdf]]Title: Crystal structure of truncated endolysin R21 from phage 21 <br />
1.7 A resolution <br />
<br />
**<b>Enterobacteria phage T4</b> 561 PDB entries<br />
***[[1swy]]Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination <br />
1.06 A resolution <br />
<br />
**<b>Escherichia phage T5</b> 1 PDB entries<br />
***[[2mxz]]Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+) <br />
N/A A resolution <br />
<br />
**<b>Enterobacteria phage lambda</b> 3 PDB entries<br />
***[[1am7]]Title: Lysozyme from bacteriophage lambda <br />
2.3 A resolution <br />
<br />
**<b>Streptococcus phage CP-7</b> 1 PDB entries<br />
***[[4cvd]]Title: Crystal structure of the central repeat of cell wall binding module of Cpl7 <br />
1.666 A resolution <br />
<br />
**<b>Enterobacteria phage P1</b> 2 PDB entries<br />
***[[1xju]]Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz <br />
1.07 A resolution <br />
<br />
**<b>Streptococcus phage Cp-1</b> 6 PDB entries<br />
***[[2j8g]]Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide) <br />
1.69 A resolution <br />
<br />
*<b>Bacteria<b> 1 PDB entries**<b>Enterobacteria phage T4</b> 1 PDB entries<br />
***[[2qb0]]Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
**<b>Escherichia coli</b> 1 PDB entries<br />
***[[2qb0]]Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
}}</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435675
NADP-dependent malic enzyme
2015-09-09T20:04:56Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
{{#tree:*<b>Eukaryota<b> (16 PDB entries)**<b>Homo sapiens</b> (1 PDB entries)<br />
***[[4uis]] <div class="pdb-prints 4uis"></div>Title: The cryoEM structure of human gamma-Secretase complex <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br />
<br />
**<b>Hevea brasiliensis</b> (7 PDB entries)<br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG <br />
1.92 A resolution <br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Hevea brasiliensis"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries)<br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme <br />
1.24 A resolution <br />
Other macromolecules also in this entry: Putative exported protein, . <br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries)<br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta <br />
2.4 A resolution <br />
<br />
<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries)<br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div>Title: Crystal Structure of Tapes japonica Lysozyme <br />
1.6 A resolution <br />
<br />
<br />
**<b>Mus musculus</b> (1 PDB entries)<br />
***[[1iak]] <div class="pdb-prints 1iak"></div>Title: HISTOCOMPATIBILITY ANTIGEN I-AK <br />
1.9 A resolution <br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br />
<br />
**<b>Bombyx mori</b> (2 PDB entries)<br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME <br />
2.5 A resolution <br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
*<b>Viruses<b> (578 PDB entries)**<b>Enterobacteria phage P22</b> (2 PDB entries)<br />
***[[2anv]] <div class="pdb-prints 2anv"></div>Title: crystal structure of P22 lysozyme mutant L86M <br />
1.04 A resolution <br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries)<br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div>Title: Crystal structure of truncated endolysin R21 from phage 21 <br />
1.7 A resolution <br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries)<br />
***[[1swy]] <div class="pdb-prints 1swy"></div>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination <br />
1.06 A resolution <br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries)<br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+) <br />
N/A A resolution <br />
<br />
<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries)<br />
***[[1am7]] <div class="pdb-prints 1am7"></div>Title: Lysozyme from bacteriophage lambda <br />
2.3 A resolution <br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries)<br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7 <br />
1.666 A resolution <br />
<br />
<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries)<br />
***[[1xju]] <div class="pdb-prints 1xju"></div>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz <br />
1.07 A resolution <br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries)<br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide) <br />
1.69 A resolution <br />
<br />
***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
*<b>Bacteria<b> (1 PDB entries)**<b>Enterobacteria phage T4</b> (1 PDB entries)<br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
<br />
**<b>Escherichia coli</b> (1 PDB entries)<br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
<br />
}}</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435674
NADP-dependent malic enzyme
2015-09-09T19:44:40Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
<br>Eukaryota (16 PDB entries): <br><br><b>Homo sapiens</b> (1 PDB entries): <br><br />
[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br/><br />
<br><b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Hevea brasiliensis"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Meretrix lusoria</b> (3 PDB entries): <br><br />
[[4pj2]] <div class="pdb-prints 4pj2"></div><br><br>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br> <br />
1.24 A resolution <br><br />
Other macromolecules also in this entry: Putative exported protein, . <br><br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Antheraea mylitta</b> (1 PDB entries): <br><br />
[[1iiz]] <div class="pdb-prints 1iiz"></div><br><br>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br> <br />
2.4 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
[[2dqa]] <div class="pdb-prints 2dqa"></div><br><br>Title: Crystal Structure of Tapes japonica Lysozyme<br> <br />
1.6 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Mus musculus</b> (1 PDB entries): <br><br />
[[1iak]] <div class="pdb-prints 1iak"></div><br><br>Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br> <br />
1.9 A resolution <br><br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br><br><br />
<br/><br />
<br><b>Bombyx mori</b> (2 PDB entries): <br><br />
[[1gd6]] <div class="pdb-prints 1gd6"></div><br><br>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br> <br />
2.5 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br>Viruses (578 PDB entries): <br><br><b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
[[2anv]] <div class="pdb-prints 2anv"></div><br><br>Title: crystal structure of P22 lysozyme mutant L86M<br> <br />
1.04 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
[[3hdf]] <div class="pdb-prints 3hdf"></div><br><br>Title: Crystal structure of truncated endolysin R21 from phage 21<br> <br />
1.7 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
[[1swy]] <div class="pdb-prints 1swy"></div><br><br>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br> <br />
1.06 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Escherichia phage T5</b> (1 PDB entries): <br><br />
[[2mxz]] <div class="pdb-prints 2mxz"></div><br><br>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br> <br />
N/A A resolution <br><br />
<br><br />
<br/><br />
<br><b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
[[1am7]] <div class="pdb-prints 1am7"></div><br><br>Title: Lysozyme from bacteriophage lambda<br> <br />
2.3 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
[[4cvd]] <div class="pdb-prints 4cvd"></div><br><br>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br> <br />
1.666 A resolution <br><br />
<br><br />
<br/><br />
<br><b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
[[1xju]] <div class="pdb-prints 1xju"></div><br><br>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br> <br />
1.07 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
[[2j8g]] <div class="pdb-prints 2j8g"></div><br><br>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br> <br />
1.69 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br>Bacteria (1 PDB entries): <br><br><b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/><br />
<br><b>Escherichia coli</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/></div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435673
NADP-dependent malic enzyme
2015-09-09T19:43:31Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
<br>*Eukaryota (16 PDB entries): <br><br><b>**Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br/><br />
<br><b>**Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Hevea brasiliensis"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>**Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br><br>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br> <br />
1.24 A resolution <br><br />
Other macromolecules also in this entry: Putative exported protein, . <br><br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>**Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br><br>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br> <br />
2.4 A resolution <br><br />
<br><br />
<br/><br />
<br><b>**Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br><br>Title: Crystal Structure of Tapes japonica Lysozyme<br> <br />
1.6 A resolution <br><br />
<br><br />
<br/><br />
<br><b>**Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br><br>Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br> <br />
1.9 A resolution <br><br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br><br><br />
<br/><br />
<br><b>**Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br><br>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br> <br />
2.5 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br>*Viruses (578 PDB entries): <br><br><b>**Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br><br>Title: crystal structure of P22 lysozyme mutant L86M<br> <br />
1.04 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>**Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br><br>Title: Crystal structure of truncated endolysin R21 from phage 21<br> <br />
1.7 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>**Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br><br>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br> <br />
1.06 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>**Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br><br>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br> <br />
N/A A resolution <br><br />
<br><br />
<br/><br />
<br><b>**Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br><br>Title: Lysozyme from bacteriophage lambda<br> <br />
2.3 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>**Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br><br>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br> <br />
1.666 A resolution <br><br />
<br><br />
<br/><br />
<br><b>**Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br><br>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br> <br />
1.07 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br><b>**Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br><br>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br> <br />
1.69 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br />
<br>*Bacteria (1 PDB entries): <br><br><b>**Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/><br />
<br><b>**Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/></div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435672
NADP-dependent malic enzyme
2015-09-09T19:42:35Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
{{#tree:id=OrganizedByTopic|openlevels=2|*<b>Eukaryota<b> (16 PDB entries):**<b>Homo sapiens</b> (1 PDB entries):<br />
***[[4uis]] <div class="pdb-prints 4uis"></div>Title: The cryoEM structure of human gamma-Secretase complex <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br />
<br />
**<b>Hevea brasiliensis</b> (7 PDB entries):<br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG <br />
1.92 A resolution <br />
<br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Hevea brasiliensis"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Meretrix lusoria</b> (3 PDB entries):<br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme <br />
1.24 A resolution <br />
Other macromolecules also in this entry: Putative exported protein, . <br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Antheraea mylitta</b> (1 PDB entries):<br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta <br />
2.4 A resolution <br />
<br />
<br />
**<b>Ruditapes philippinarum</b> (1 PDB entries):<br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div>Title: Crystal Structure of Tapes japonica Lysozyme <br />
1.6 A resolution <br />
<br />
<br />
**<b>Mus musculus</b> (1 PDB entries):<br />
***[[1iak]] <div class="pdb-prints 1iak"></div>Title: HISTOCOMPATIBILITY ANTIGEN I-AK <br />
1.9 A resolution <br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br />
<br />
**<b>Bombyx mori</b> (2 PDB entries):<br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME <br />
2.5 A resolution <br />
<br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
*<b>Viruses<b> (578 PDB entries):**<b>Enterobacteria phage P22</b> (2 PDB entries):<br />
***[[2anv]] <div class="pdb-prints 2anv"></div>Title: crystal structure of P22 lysozyme mutant L86M <br />
1.04 A resolution <br />
<br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Enterobacteria phage P21</b> (2 PDB entries):<br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div>Title: Crystal structure of truncated endolysin R21 from phage 21 <br />
1.7 A resolution <br />
<br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Enterobacteria phage T4</b> (561 PDB entries):<br />
***[[1swy]] <div class="pdb-prints 1swy"></div>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination <br />
1.06 A resolution <br />
<br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Escherichia phage T5</b> (1 PDB entries):<br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+) <br />
N/A A resolution <br />
<br />
<br />
**<b>Enterobacteria phage lambda</b> (3 PDB entries):<br />
***[[1am7]] <div class="pdb-prints 1am7"></div>Title: Lysozyme from bacteriophage lambda <br />
2.3 A resolution <br />
<br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Streptococcus phage CP-7</b> (1 PDB entries):<br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7 <br />
1.666 A resolution <br />
<br />
<br />
**<b>Enterobacteria phage P1</b> (2 PDB entries):<br />
***[[1xju]] <div class="pdb-prints 1xju"></div>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz <br />
1.07 A resolution <br />
<br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
**<b>Streptococcus phage Cp-1</b> (6 PDB entries):<br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide) <br />
1.69 A resolution <br />
<br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries]<br />
*<b>Bacteria<b> (1 PDB entries):**<b>Enterobacteria phage T4</b> (1 PDB entries):<br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
<br />
**<b>Escherichia coli</b> (1 PDB entries):<br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. <br />
2.56 A resolution <br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br />
<br />
}}</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435671
NADP-dependent malic enzyme
2015-09-09T19:37:54Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
{{#tree:id=OrganizedByTopic|openlevels=0|<br>*Eukaryota (16 PDB entries): <br><br><b>**Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br/><br><b>**Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Hevea brasiliensis"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br><b>**Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br><br>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br> <br />
1.24 A resolution <br><br />
Other macromolecules also in this entry: Putative exported protein, . <br><br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br><b>**Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br><br>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br> <br />
2.4 A resolution <br><br />
<br><br />
<br/><br><b>**Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br><br>Title: Crystal Structure of Tapes japonica Lysozyme<br> <br />
1.6 A resolution <br><br />
<br><br />
<br/><br><b>**Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br><br>Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br> <br />
1.9 A resolution <br><br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br><br><br />
<br/><br><b>**Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br><br>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br> <br />
2.5 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br>*Viruses (578 PDB entries): <br><br><b>**Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br><br>Title: crystal structure of P22 lysozyme mutant L86M<br> <br />
1.04 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br><b>**Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br><br>Title: Crystal structure of truncated endolysin R21 from phage 21<br> <br />
1.7 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br><b>**Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br><br>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br> <br />
1.06 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br><b>**Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br><br>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br> <br />
N/A A resolution <br><br />
<br><br />
<br/><br><b>**Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br><br>Title: Lysozyme from bacteriophage lambda<br> <br />
2.3 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br><b>**Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br><br>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br> <br />
1.666 A resolution <br><br />
<br><br />
<br/><br><b>**Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br><br>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br> <br />
1.07 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br><b>**Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br><br>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br> <br />
1.69 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries] <br/><br>*Bacteria (1 PDB entries): <br><br><b>**Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/><br><b>**Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br/>}}</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435670
NADP-dependent malic enzyme
2015-09-09T19:30:53Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
{{#tree:id=OrganizedByTopic|openlevels=0|<br>*Eukaryota (16 PDB entries): <br><br><b>**Homo sapiens</b> (1 PDB entries): <br><br />
***[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br><b>**Hevea brasiliensis</b> (7 PDB entries): <br><br />
***[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Hevea brasiliensis"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>**Meretrix lusoria</b> (3 PDB entries): <br><br />
***[[4pj2]] <div class="pdb-prints 4pj2"></div><br><br>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br> <br />
1.24 A resolution <br><br />
Other macromolecules also in this entry: Putative exported protein, . <br><br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>**Antheraea mylitta</b> (1 PDB entries): <br><br />
***[[1iiz]] <div class="pdb-prints 1iiz"></div><br><br>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br> <br />
2.4 A resolution <br><br />
<br><br />
<br><b>**Ruditapes philippinarum</b> (1 PDB entries): <br><br />
***[[2dqa]] <div class="pdb-prints 2dqa"></div><br><br>Title: Crystal Structure of Tapes japonica Lysozyme<br> <br />
1.6 A resolution <br><br />
<br><br />
<br><b>**Mus musculus</b> (1 PDB entries): <br><br />
***[[1iak]] <div class="pdb-prints 1iak"></div><br><br>Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br> <br />
1.9 A resolution <br><br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br><br><br />
<br><b>**Bombyx mori</b> (2 PDB entries): <br><br />
***[[1gd6]] <div class="pdb-prints 1gd6"></div><br><br>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br> <br />
2.5 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries]<br>*Viruses (578 PDB entries): <br><br><b>**Enterobacteria phage P22</b> (2 PDB entries): <br><br />
***[[2anv]] <div class="pdb-prints 2anv"></div><br><br>Title: crystal structure of P22 lysozyme mutant L86M<br> <br />
1.04 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>**Enterobacteria phage P21</b> (2 PDB entries): <br><br />
***[[3hdf]] <div class="pdb-prints 3hdf"></div><br><br>Title: Crystal structure of truncated endolysin R21 from phage 21<br> <br />
1.7 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>**Enterobacteria phage T4</b> (561 PDB entries): <br><br />
***[[1swy]] <div class="pdb-prints 1swy"></div><br><br>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br> <br />
1.06 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>**Escherichia phage T5</b> (1 PDB entries): <br><br />
***[[2mxz]] <div class="pdb-prints 2mxz"></div><br><br>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br> <br />
N/A A resolution <br><br />
<br><br />
<br><b>**Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
***[[1am7]] <div class="pdb-prints 1am7"></div><br><br>Title: Lysozyme from bacteriophage lambda<br> <br />
2.3 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>**Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
***[[4cvd]] <div class="pdb-prints 4cvd"></div><br><br>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br> <br />
1.666 A resolution <br><br />
<br><br />
<br><b>**Enterobacteria phage P1</b> (2 PDB entries): <br><br />
***[[1xju]] <div class="pdb-prints 1xju"></div><br><br>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br> <br />
1.07 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>**Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
***[[2j8g]] <div class="pdb-prints 2j8g"></div><br><br>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br> <br />
1.69 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries]<br>*Bacteria (1 PDB entries): <br><br><b>**Enterobacteria phage T4</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br><b>**Escherichia coli</b> (1 PDB entries): <br><br />
***[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
}}</div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435163
NADP-dependent malic enzyme
2015-09-09T15:42:06Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
<br>Eukaryota (16 PDB entries): <br><br><b>Homo sapiens</b> (1 PDB entries): <br><br />
[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://pdbe.org/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br><b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Hevea brasiliensis"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Meretrix lusoria</b> (3 PDB entries): <br><br />
[[4pj2]] <div class="pdb-prints 4pj2"></div><br><br>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br> <br />
1.24 A resolution <br><br />
Other macromolecules also in this entry: Putative exported protein, . <br><br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Antheraea mylitta</b> (1 PDB entries): <br><br />
[[1iiz]] <div class="pdb-prints 1iiz"></div><br><br>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br> <br />
2.4 A resolution <br><br />
<br><br />
<br><b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
[[2dqa]] <div class="pdb-prints 2dqa"></div><br><br>Title: Crystal Structure of Tapes japonica Lysozyme<br> <br />
1.6 A resolution <br><br />
<br><br />
<br><b>Mus musculus</b> (1 PDB entries): <br><br />
[[1iak]] <div class="pdb-prints 1iak"></div><br><br>Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br> <br />
1.9 A resolution <br><br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br><br><br />
<br><b>Bombyx mori</b> (2 PDB entries): <br><br />
[[1gd6]] <div class="pdb-prints 1gd6"></div><br><br>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br> <br />
2.5 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries]<br>Viruses (578 PDB entries): <br><br><b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
[[2anv]] <div class="pdb-prints 2anv"></div><br><br>Title: crystal structure of P22 lysozyme mutant L86M<br> <br />
1.04 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
[[3hdf]] <div class="pdb-prints 3hdf"></div><br><br>Title: Crystal structure of truncated endolysin R21 from phage 21<br> <br />
1.7 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
[[1swy]] <div class="pdb-prints 1swy"></div><br><br>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br> <br />
1.06 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Escherichia phage T5</b> (1 PDB entries): <br><br />
[[2mxz]] <div class="pdb-prints 2mxz"></div><br><br>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br> <br />
N/A A resolution <br><br />
<br><br />
<br><b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
[[1am7]] <div class="pdb-prints 1am7"></div><br><br>Title: Lysozyme from bacteriophage lambda<br> <br />
2.3 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
[[4cvd]] <div class="pdb-prints 4cvd"></div><br><br>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br> <br />
1.666 A resolution <br><br />
<br><br />
<br><b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
[[1xju]] <div class="pdb-prints 1xju"></div><br><br>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br> <br />
1.07 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
[[2j8g]] <div class="pdb-prints 2j8g"></div><br><br>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br> <br />
1.69 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries]<br>Bacteria (1 PDB entries): <br><br><b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br><b>Escherichia coli</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br></div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435138
NADP-dependent malic enzyme
2015-09-09T15:40:13Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
<br>Eukaryota (16 PDB entries): <br><br><b>Homo sapiens</b> (1 PDB entries): <br><br />
[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://www.ebi.ac.uk/pdbe/entry/emdb/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br><b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Hevea brasiliensis"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Meretrix lusoria</b> (3 PDB entries): <br><br />
[[4pj2]] <div class="pdb-prints 4pj2"></div><br><br>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br> <br />
1.24 A resolution <br><br />
Other macromolecules also in this entry: Putative exported protein, . <br><br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Antheraea mylitta</b> (1 PDB entries): <br><br />
[[1iiz]] <div class="pdb-prints 1iiz"></div><br><br>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br> <br />
2.4 A resolution <br><br />
<br><br />
<br><b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
[[2dqa]] <div class="pdb-prints 2dqa"></div><br><br>Title: Crystal Structure of Tapes japonica Lysozyme<br> <br />
1.6 A resolution <br><br />
<br><br />
<br><b>Mus musculus</b> (1 PDB entries): <br><br />
[[1iak]] <div class="pdb-prints 1iak"></div><br><br>Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br> <br />
1.9 A resolution <br><br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br><br><br />
<br><b>Bombyx mori</b> (2 PDB entries): <br><br />
[[1gd6]] <div class="pdb-prints 1gd6"></div><br><br>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br> <br />
2.5 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries]<br>Viruses (578 PDB entries): <br><br><b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
[[2anv]] <div class="pdb-prints 2anv"></div><br><br>Title: crystal structure of P22 lysozyme mutant L86M<br> <br />
1.04 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
[[3hdf]] <div class="pdb-prints 3hdf"></div><br><br>Title: Crystal structure of truncated endolysin R21 from phage 21<br> <br />
1.7 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Enterobacteria phage T4</b> (561 PDB entries): <br><br />
[[1swy]] <div class="pdb-prints 1swy"></div><br><br>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br> <br />
1.06 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Escherichia phage T5</b> (1 PDB entries): <br><br />
[[2mxz]] <div class="pdb-prints 2mxz"></div><br><br>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br> <br />
N/A A resolution <br><br />
<br><br />
<br><b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
[[1am7]] <div class="pdb-prints 1am7"></div><br><br>Title: Lysozyme from bacteriophage lambda<br> <br />
2.3 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
[[4cvd]] <div class="pdb-prints 4cvd"></div><br><br>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br> <br />
1.666 A resolution <br><br />
<br><br />
<br><b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
[[1xju]] <div class="pdb-prints 1xju"></div><br><br>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br> <br />
1.07 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
[[2j8g]] <div class="pdb-prints 2j8g"></div><br><br>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br> <br />
1.69 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries]<br>Bacteria (1 PDB entries): <br><br><b>Enterobacteria phage T4</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br><br />
<br><b>Escherichia coli</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br></div>
PDBe
https://proteopedia.org/index.php?title=NADP-dependent_malic_enzyme&diff=2435103
NADP-dependent malic enzyme
2015-09-09T15:16:07Z
<p>PDBe: </p>
<hr />
<div>== Lysozyme ==<br />
<StructureSection load='1swy' size='340' side='right' caption='Caption for this structure' scene=''><br />
Best example is 1swy<br><br />
Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.<br />
== Function ==<br />
lysozyme activity<br><br />
catalytic activity<br><br />
hydrolase activity<br><br />
hydrolase activity, acting on glycosyl bonds<br><br />
carbon-oxygen lyase activity, acting on polysaccharides<br><br />
lyase activity<br><br />
chitinase activity<br><br />
hydrolase activity, hydrolyzing O-glycosyl compounds<br><br />
sequence-specific DNA binding<br><br />
<br />
== Disease ==<br />
<br />
== Relevance ==<br />
<br />
== Structural highlights ==<br />
== Biological process ==<br />
Is involved in the following biological processes:<br><br />
cell wall macromolecule catabolic process<br><br />
peptidoglycan catabolic process<br><br />
metabolic process<br><br />
defense response to bacterium<br><br />
cytolysis<br><br />
viral release from host cell<br><br />
carbohydrate metabolic process<br><br />
chitin catabolic process<br><br />
polysaccharide catabolic process<br><br />
cytolysis by virus of host cell<br><br />
cell wall organization<br><br />
== In structures ==<br />
Lysozyme is found in 595 PDB entries<br><br />
<br><b>Homo sapiens</b> (1 PDB entries): <br><br />
[[4uis]] <div class="pdb-prints 4uis"></div><br><br>Title: The cryoEM structure of human gamma-Secretase complex<br> <br />
Experimental EM map [http://www.ebi.ac.uk/pdbe/entry/emdb/emd-2974 emd-2974]. <br><br />
4.4 A resolution <br><br />
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, . <br><br><br />
<br><b>Enterobacteria phage P22</b> (2 PDB entries): <br><br />
[[2anv]] <div class="pdb-prints 2anv"></div><br><br>Title: crystal structure of P22 lysozyme mutant L86M<br> <br />
1.04 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Enterobacteria phage P21</b> (2 PDB entries): <br><br />
[[3hdf]] <div class="pdb-prints 3hdf"></div><br><br>Title: Crystal structure of truncated endolysin R21 from phage 21<br> <br />
1.7 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Hevea brasiliensis</b> (7 PDB entries): <br><br />
[[1kqy]] <div class="pdb-prints 1kqy"></div><br><br>Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG<br> <br />
1.92 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Hevea brasiliensis"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Escherichia phage T5</b> (1 PDB entries): <br><br />
[[2mxz]] <div class="pdb-prints 2mxz"></div><br><br>Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)<br> <br />
N/A A resolution <br><br />
<br><br />
<br><b>Streptococcus phage CP-7</b> (1 PDB entries): <br><br />
[[4cvd]] <div class="pdb-prints 4cvd"></div><br><br>Title: Crystal structure of the central repeat of cell wall binding module of Cpl7<br> <br />
1.666 A resolution <br><br />
<br><br />
<br><b>Antheraea mylitta</b> (1 PDB entries): <br><br />
[[1iiz]] <div class="pdb-prints 1iiz"></div><br><br>Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta<br> <br />
2.4 A resolution <br><br />
<br><br />
<br><b>Mus musculus</b> (1 PDB entries): <br><br />
[[1iak]] <div class="pdb-prints 1iak"></div><br><br>Title: HISTOCOMPATIBILITY ANTIGEN I-AK<br> <br />
1.9 A resolution <br><br />
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain. <br><br><br />
<br><b>Bombyx mori</b> (2 PDB entries): <br><br />
[[1gd6]] <div class="pdb-prints 1gd6"></div><br><br>Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME<br> <br />
2.5 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Streptococcus phage Cp-1</b> (6 PDB entries): <br><br />
[[2j8g]] <div class="pdb-prints 2j8g"></div><br><br>Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)<br> <br />
1.69 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Enterobacteria phage T4</b> (562 PDB entries): <br><br />
[[1swy]] <div class="pdb-prints 1swy"></div><br><br>Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination<br> <br />
1.06 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Enterobacteria phage P1</b> (2 PDB entries): <br><br />
[[1xju]] <div class="pdb-prints 1xju"></div><br><br>Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz<br> <br />
1.07 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Enterobacteria phage lambda</b> (3 PDB entries): <br><br />
[[1am7]] <div class="pdb-prints 1am7"></div><br><br>Title: Lysozyme from bacteriophage lambda<br> <br />
2.3 A resolution <br><br />
<br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Meretrix lusoria</b> (3 PDB entries): <br><br />
[[4pj2]] <div class="pdb-prints 4pj2"></div><br><br>Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme<br> <br />
1.24 A resolution <br><br />
Other macromolecules also in this entry: Putative exported protein, . <br><br><br />
[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific:"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries]<br><b>Ruditapes philippinarum</b> (1 PDB entries): <br><br />
[[2dqa]] <div class="pdb-prints 2dqa"></div><br><br>Title: Crystal Structure of Tapes japonica Lysozyme<br> <br />
1.6 A resolution <br><br />
<br><br />
<br><b>Escherichia coli</b> (1 PDB entries): <br><br />
[[2qb0]] <div class="pdb-prints 2qb0"></div><br><br>Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.<br> <br />
2.56 A resolution <br><br />
Other macromolecules also in this entry: Transcription factor ETV6, . <br><br></div>
PDBe