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https://proteopedia.org/index.php?title=Shikimate_dehydrogenase&diff=2065816
Shikimate dehydrogenase
2014-11-20T22:39:17Z
<p>Sohail Jooma: </p>
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{{STRUCTURE_2ev9| PDB=2ev9 | SIZE=350| SCENE= |right|CAPTION=Shikimate dehydrogenase dimer complex with shikimate, sulfate and NADP [[2ev9]] }}<br />
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'''Shikimate dehydrogenase''' (AroE) catalyzes the conversion of shikimate and NADP+ to 3-dihydroshikimate, NADPH and H+. It is part of the shikimate pathway which is responsible for the biosynthesis of phenylalanine, tyrosine and tryptophan. This pathway is found in bacteria, fungi, plants, algae and parasites and is missing in animals and humans.<br />
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== 3D Structures of shikimate dehydrogenase ==<br />
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}<br />
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===AroE===<br />
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[[1p74]], [[1p77]] – AroE – ''Haemophilus influenzae''<br /><br />
[[1wxd]] – TtAroE – ''Thermus thermophilus'' <br /><br />
[[2hk7]], [[2hk8]] – AaAroE – ''Aquifex aeolicus'' <br /><br />
[[2egg]] – AroE – ''Geobacillus kaustophilus'' <br /><br />
[[3fbt]] – AroE/chorismate mutase – ''Clostridium acetobutylicum'' <br /><br />
[[3don]] – SeAroE – ''Staphylococcus epidermidis'' <br /><br />
[[3o8q]] – VcAroE – ''Vibrio cholerae'' <br /><br />
[[3pwz]] – AroE 3 – ''Pseudomonas putida'' <br /><br />
[[3phg]] – HpAroE – ''Helicobacter pylori'' <br /><br />
[[4foo]], [[4fpx]] – HpAroE (mutant) <br /><br />
[[3u62]] – AroE – ''Thermotoga maritima'' <br /><br />
[[2nlo]] – CgAroE – ''Corynebacterium glutamicum''<br /><br />
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===AroE complex with NADP===<br />
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[[1nyt]], [[1vi2]] – EcAroE + NADP – ''Escherichia coli''<br /><br />
[[1nvt]] – MjAroE + NADP – ''Methanocaldococcus jannaschii''<br /><br />
[[2cy0]] – TtAroE + NADP <br /><br />
[[3toz]] – LmAroE + NAD – ''Listeria monocytogenes''<br /><br />
[[3t4e]] – AroE + NAD – ''Salmonella enterica''<br /><br />
[[3jyo]] - CgAroE + NAD <br /><br />
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===AroE complex with shikimate===<br />
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[[2d5c]] – TtAroE + shikimate <br /><br />
[[3doo]] – SeAroE + shikimate <br /><br />
[[3pgj]] – VcAroE + shikimate <br /><br />
[[3phh]] – HpAroE + shikimate <br /><br />
[[4fos]], [[4fq8]], [[4fr5]], [[4fsh]] – HpAroE (mutant) + shikimate <br /><br />
[[3phj]] – HpAroE + 3-dihydroshikimate <br /><br />
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===AroE complex with NADP and shikimate===<br />
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[[2ev9]] – TtAroE + shikimate + NADP <br /><br />
[[2hk9]] – AaAroE + shikimate + NADP <br /><br />
[[3sef]] – VcAroE + shikimate + NADP <br /><br />
[[3tnl]] – LmAroE + shikimate + NAD <br /><br />
[[3phi]] – HpAroE + shikimate + NADP <br /><br />
[[3jyp]] - CgAroE + quinate + NAD <br /><br />
[[3jyq]] - CgAroE + shikimate + NAD <br /><br />
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[[Category:Topic Page]]</div>
Sohail Jooma