2eix | pdb_00002eix

The Structure of Physarum polycephalum cytochrome b5 reductase

spinqualitylabelsall models 2eix, resolution 1.56Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2eix is a 2 chain structure with sequence from Physarum polycephalum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.56Å Ligands: FAD, GOL, IOD, NA Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q1HA49_PHYPO Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed Physarum polycephalum cytochrome b(5) reductase catalyzes the reduction of cytochrome b(5) by NADH. The structure of P. polycephalum cytochrome b(5) reductase was determined at a resolution of 1.56 A. The molecular structure was compared with that of human cytochrome b(5) reductase, which had previously been determined at 1.75 A resolution [Bando et al. (2004), Acta Cryst. D60, 1929-1934]. The high-resolution structure revealed conformational differences between the two enzymes in the adenosine moiety of the FAD, the lid region and the linker region. The structural properties of both proteins were inspected in terms of hydrogen bonding, ion pairs, accessible surface area and cavity volume. The differences in these structural properties between the two proteins were consistent with estimates of their thermostabilities obtained from differential scanning calorimetry data. Structure of Physarum polycephalum cytochrome b5 reductase at 1.56 A resolution.,Kim S, Suga M, Ogasahara K, Ikegami T, Minami Y, Yubisui T, Tsukihara T Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt, 4):274-9. Epub 2007 Mar 23. PMID:17401193 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also NADH-cytochrome b5 reductase

Proteopedia Page Contributors and Editors (what is this?)

OCA