5hdt | pdb_00005hdt

Human cohesin regulator Pds5B bound to a Wapl peptide

spinqualitylabelsall models 5hdt, resolution 2.71Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5hdt is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.711Å Ligands: IHP, MSE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PDS5B_HUMAN Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.

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