5zmb | pdb_00005zmb

A-ubiquitin like protein from the trypanosoma brucei

spinqualitylabelsall models 5zmb Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5zmb is a 1 chain structure with sequence from Trypanosoma brucei brucei TREU927. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q583M0_TRYB2 Publication Abstract from PubMed Ubiquitin-like proteins, similar to ubiquitin, can either exist freely or be covalently attached to other proteins via an enzymatic cascade. The ubiquitin-like proteins play roles in multiple biological processes including transcription, stress responses, DNA repair and so on. In this study, a novel ubiquitin-like protein (TbUbl11) was identified in Trypanosoma brucei. The solution structure of TbUbl11 was solved by NMR spectroscopy. TbUbl11 adopts a conserved beta-grasp fold composed by a five-stranded beta-sheet curling around a central alpha-helix, similar to other ubiquitin-like proteins. Meanwhile, some differences between TbUbl11 and other ubiquitin-like proteins were also identified. Additionally, we revealed that TbUbl11 is located in the whole cell body of procyclic-form T. brucei. This article is protected by copyright. All rights reserved. Solution structure of a ubiquitin-like protein from Trypanosoma brucei.,Mi J, Zhang J, Liao S, Tu X Protein Sci. 2018 Jul 29. doi: 10.1002/pro.3492. PMID:30058168 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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