6m86 | pdb_00006m86
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Crystal Structure of Inward Rectifier Kir2.2 Force Open Mutant
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Structural highlights
FunctionKCJ12_CHICK Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification is probably due to the blockage of outward current by cytoplasmic polyamines and/or magnesium ions.[1] [2] See AlsoReferences
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This page was last modified 06:26, 11 October 2023.