7k7v
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The X-ray crystal structure of SSR4, an S. pombe chromatin remodelling protein: iodide derivative
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Structural highlights
FunctionSSR4_SCHPO Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes. Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.[1] References
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This page was last modified 14:55, 6 March 2024.