9sfw

Structure of Pex8 in complex with peroxisomal receptor Pex5

spinqualitylabelsall models 9sfw, resolution 4.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9sfw is a 2 chain structure with sequence from Komagataella pastoris. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 4.5Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PEX8_PICPA Essential component of the machinery required for the import of both PTS1 and PTS2 (and perhaps all) peroxisomal matrix proteins (PubMed:7738036). Binding of PEX8 to the N-terminus of PEX5 cargo receptor induces a conformational change of the TPR domains and decrease their binding affinity to cargo, facilitating the release of the PTS1 proteins within the peroxisome (PubMed:23902771).

Proteopedia Page Contributors and Editors (what is this?)

OCA