Cholesterol esterase

spinqualitylabelsall models Glycosylated cholesterol esterase dimer complex with bile acid (PDB entry 1llf) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Cholesterol esterase (ChoE) also named bile-salt activated lipase or sterol esterase catalyzes the hydrolytic cleavage of cholesterol, other sterol esters and triglycerides. Disease Deficiency of this enzyme causes Wolman’s disease and cholesteryl ester storage disease. Structural highlights ChoE ligand-binding tunnel is ca. 30 A long (Hydrophobic, Polar). ChoE has the polar catalytic triad Ser-His-Glu at the opening and hydrophobic residues lining the bottom cup. 3D structures of cholesterol esterase Cholesterol esterase 3D structures

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky