View source for 10mt


==C2 symmetry expanded and subtracted 20S Proteasome, Blm10, Fub1 Complex Halfmer==
<StructureSection load='10mt' size='340' side='right'caption='[[10mt]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[10mt]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10MT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10MT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10mt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10mt OCA], [https://pdbe.org/10mt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10mt RCSB], [https://www.ebi.ac.uk/pdbsum/10mt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10mt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PSA1_YEAST PSA1_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Fermin Perez E]]
[[Category: Hanna J]]
[[Category: Rawson S]]
[[Category: Venclovaite U]]
[[Category: Walsh Jr RM]]