View source for 43jx


==NMR Solution Structure of the Monomeric Catalytic C-terminal Lobe of the HECW2 HECT E3 Ubiquitin Ligase==
<StructureSection load='43jx' size='340' side='right'caption='[[43jx]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[43jx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=43JX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=43JX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR,  models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=43jx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=43jx OCA], [https://pdbe.org/43jx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=43jx RCSB], [https://www.ebi.ac.uk/pdbsum/43jx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=43jx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HECW2_HUMAN HECW2_HUMAN] E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Dag C]]
[[Category: Kazar AE]]
[[Category: Lambert M]]
[[Category: Lee W]]
[[Category: Tonelli M]]