View source for 6aca


==Crystal structure of Mycobacterium tuberculosis Mfd at 3.6 A resolution==
<StructureSection load='6aca' size='340' side='right'caption='[[6aca]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6aca]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ACA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ACA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6aca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aca OCA], [https://pdbe.org/6aca PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6aca RCSB], [https://www.ebi.ac.uk/pdbsum/6aca PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6aca ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MFD_MYCTU MFD_MYCTU] Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.[HAMAP-Rule:MF_00969]

==See Also==
*[[Transcription-repair coupling factor 3D structures|Transcription-repair coupling factor 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Fox GC]]
[[Category: Nagaraja V]]
[[Category: Natesh R]]
[[Category: Putta S]]
[[Category: Rao DN]]
[[Category: Walsh MA]]