View source for 7fcy


==Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor==
<StructureSection load='7fcy' size='340' side='right'caption='[[7fcy]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7fcy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FCY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.848&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=47Z:(1S)-2-methyl-1-(2-methyl-1,2,4-triazol-3-yl)propan-1-amine'>47Z</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fcy OCA], [https://pdbe.org/7fcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fcy RCSB], [https://www.ebi.ac.uk/pdbsum/7fcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fcy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HIS7_MYCTU HIS7_MYCTU] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Biswal BK]]
[[Category: Pal RK]]
[[Category: Tiwari S]]