View source for 7kzp


==Structure of the human Fanconi anaemia Core complex==
<StructureSection load='7kzp' size='340' side='right'caption='[[7kzp]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7kzp]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KZP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kzp OCA], [https://pdbe.org/7kzp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kzp RCSB], [https://www.ebi.ac.uk/pdbsum/7kzp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kzp ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/FANCA_HUMAN FANCA_HUMAN] Fanconi anemia. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/FANCA_HUMAN FANCA_HUMAN] DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Pavletich NP]]
[[Category: Wang SL]]