View source for 8fiy


==Cryo-EM structure of E. coli RNA polymerase Elongation complex in the Transcription-Translation Complex (RNAP in an anti-swiveled conformation)==
<StructureSection load='8fiy' size='340' side='right'caption='[[8fiy]], [[Resolution|resolution]] 7.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8fiy]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Escherichia_phage_Lambda Escherichia phage Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FIY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fiy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fiy OCA], [https://pdbe.org/8fiy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fiy RCSB], [https://www.ebi.ac.uk/pdbsum/8fiy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fiy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]

==See Also==
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Escherichia phage Lambda]]
[[Category: Large Structures]]
[[Category: Bustamante C]]
[[Category: Canari C]]
[[Category: Florez Ariza A]]
[[Category: Grob P]]
[[Category: Nogales E]]
[[Category: Tong A]]
[[Category: Wee L]]