View source for 8pmx


==rat HEV P domain in complex with glycan-sensitive nAb p60.12==
<StructureSection load='8pmx' size='340' side='right'caption='[[8pmx]], [[Resolution|resolution]] 3.92&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8pmx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_E_virus_rat/R63/DEU/2009 Hepatitis E virus rat/R63/DEU/2009] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PMX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PMX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.922&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pmx OCA], [https://pdbe.org/8pmx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pmx RCSB], [https://www.ebi.ac.uk/pdbsum/8pmx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pmx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/E0XL23_9VIRU E0XL23_9VIRU] Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter. The capsid is composed of 60 copies linked to each other. Binds to the 5' end of the genomic RNA to mediate genome encapsidation.[RuleBase:RU363023]  Plays a role in the inhibition of host antibody-mediated neutralization without blocking viral cell entry.[RuleBase:RU363023]
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</StructureSection>
[[Category: Hepatitis E virus rat/R63/DEU/2009]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Krey T]]
[[Category: Ssebyatika G]]