View source for 9zaz


==Crystal structure of human MGAT1 in complex with UDP.==
<StructureSection load='9zaz' size='340' side='right'caption='[[9zaz]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9zaz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZAZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PG6:1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE'>PG6</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zaz OCA], [https://pdbe.org/9zaz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zaz RCSB], [https://www.ebi.ac.uk/pdbsum/9zaz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zaz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MGAT1_HUMAN MGAT1_HUMAN] Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.<ref>PMID:1702225</ref> <ref>PMID:36280670</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Handing KB]]
[[Category: Whittington DA]]