View source for 30dr


==Dynein-Dynactin-RAB11FIP3 complex - composite==
<StructureSection load='30dr' size='340' side='right'caption='[[30dr]], [[Resolution|resolution]] 10.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[30dr]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=30DR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=30DR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=30dr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=30dr OCA], [https://pdbe.org/30dr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=30dr RCSB], [https://www.ebi.ac.uk/pdbsum/30dr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=30dr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RFIP3_HUMAN RFIP3_HUMAN] Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton.<ref>PMID:15601896</ref> <ref>PMID:17394487</ref> <ref>PMID:19327867</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Carter AP]]
[[Category: D'Amico EA]]