View source for 6ogr


==X-ray crystal structure of darunavir-resistant HIV-1 protease (P30) in complex with GRL-142==
<StructureSection load='6ogr' size='340' side='right'caption='[[6ogr]], [[Resolution|resolution]] 1.28&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6ogr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OGR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OGR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.28&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7OA:(3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl+[(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate'>7OA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ogr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ogr OCA], [https://pdbe.org/6ogr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ogr RCSB], [https://www.ebi.ac.uk/pdbsum/6ogr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ogr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O38885_9HIV1 O38885_9HIV1] 
__TOC__
</StructureSection>
[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Aoki M]]
[[Category: Aoki-Ogata H]]
[[Category: Bulut H]]
[[Category: Ghosh AK]]
[[Category: Hattori SI]]
[[Category: Hayashi H]]
[[Category: Mitsuya H]]