View source for 6wg7


==Coordinates of NanR dimer fitted in Hexameric NanR-DNA hetero-complex cryo-EM map==
<StructureSection load='6wg7' size='340' side='right'caption='[[6wg7]], [[Resolution|resolution]] 8.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6wg7]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WG7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wg7 OCA], [https://pdbe.org/6wg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wg7 RCSB], [https://www.ebi.ac.uk/pdbsum/6wg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wg7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NANR_ECOLI NANR_ECOLI] Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids (PubMed:9864311, PubMed:12897000, PubMed:23935044). Represses expression of the nanATEK-yhcH, nanCMS and yjhBC operons. Acts by binding directly to the Nan box, a region of approximately 30 bp covering the promoter region (PubMed:23935044).<ref>PMID:12897000</ref> <ref>PMID:23935044</ref> <ref>PMID:9864311</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Amy H]]
[[Category: Borries D]]
[[Category: Emre B]]
[[Category: Georg R]]
[[Category: Hariprasad V]]
[[Category: Horne C]]
[[Category: Michael G]]
[[Category: Rachel N]]
[[Category: Renwick D]]
[[Category: Santosh P]]